ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry O67886

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name HEMN_AQUAE
Primary accession number O67886
Secondary accession numbers None
Integrated into Swiss-Prot on December 15, 1998
Sequence was last modified on August 1, 1998 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 54)
Name and origin of the protein
Protein name Oxygen-independent coproporphyrinogen III oxidase
Synonyms Coproporphyrinogenase
Coprogen oxidase
EC 1.3.99.22
Gene name
Name: hemN
OrderedLocusNames: aq_2124
From
Aquifex aeolicus [TaxID: 63363] [HAMAP proteome]
Taxonomy Bacteria; Aquificae; Aquificales; Aquificaceae; Aquifex.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=VF5;
DOI=10.1038/32831; PubMed=9537320 [NCBI, ExPASy, EBI, Israel, Japan]
Deckert G., Warren P.V., Gaasterland T., Young W.G., Lenox A.L., Graham D.E., Overbeek R., Snead M.A., Keller M., Aujay M., Huber R., Feldman R.A., Short J.M., Olsen G.J., Swanson R.V.;
"The complete genome of the hyperthermophilic bacterium Aquifex aeolicus.";
Nature 392:353-358(1998).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE000657; AAC07846.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR B70482; B70482.
RefSeq NP_214455.1; -.
3D structure databases
ModBase O67886.
Enzyme and pathway databases
BioCyc AAEO224324:AQ_2124-MON; -.
Family and domain databases
InterPro IPR006638; Elp3/MiaB/NifB.
IPR004558; HemN.
IPR010723; HemN_C.
IPR007197; Radical_SAM.
Graphical view of domain structure.
Pfam PF06969; HemN_C; 1.
PF04055; Radical_SAM; 1.
Pfam graphical view of domain structure.
SMART SM00729; Elp3; 1.
SMART graphical view of domain structure.
TIGRFAMs TIGR00538; hemN; 1.
BLOCKS O67886.
Genome annotation databases
GeneID 1193875; -.
GenomeReviews AE000657_GR; aq_2124.
KEGG aae:aq_2124; -.
NMPDR fig|224324.1.peg.1470; -.
Phylogenomic databases
HOGENOM O67886; -.
Genome annotation databases
CMR O67886; aq_2124.
Other
ProtoNet O67886.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
4Fe-4S; Complete proteome; Cytoplasm; Iron; Iron-sulfur; Metal-binding; Oxidoreductase; Porphyrin biosynthesis; S-adenosyl-L-methionine.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   456  456     Oxygen-independent coproporphyrinogen III oxidase. PRO_0000109938
REGION   113   114  2     S-adenosyl-L-methionine 2 binding (By similarity). 
METAL   61    61        Iron-sulfur (4Fe-4S-S-AdoMet) (By similarity). 
METAL   65    65        Iron-sulfur (4Fe-4S-S-AdoMet) (By similarity). 
METAL   68    68        Iron-sulfur (4Fe-4S-S-AdoMet) (By similarity). 
BINDING   55    55        S-adenosyl-L-methionine 1 (By similarity). 
BINDING   67    67        S-adenosyl-L-methionine 2; via carbonyl oxygen (By similarity). 
BINDING   112   112        S-adenosyl-L-methionine 1; via amide nitrogen and carbonyl oxygen (By similarity). 
BINDING   145   145        S-adenosyl-L-methionine 1 (By similarity). 
BINDING   172   172        S-adenosyl-L-methionine 2 (By similarity). 
BINDING   184   184        S-adenosyl-L-methionine 2 (By similarity). 
BINDING   209   209        S-adenosyl-L-methionine 2 (By similarity). 
Sequence information
Length: 456 AA [This is the length of the unprocessed precursor] Molecular weight: 53785 Da [This is the MW of the unprocessed precursor] CRC64: 4E494103B8EF6342 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MKAEFDKELI KKYDRPGPRY TSYPPATEFT EEVKEDEYVK RLIKSNERKT PLSLYFHIPF 

        70         80         90        100        110        120 
CEQRCLYCGC NVIISHRKGI EEPYLERVCR EMDLVSQYLD KDRKVIQLHW GGGTPNYLSP 

       130        140        150        160        170        180 
EQIKWFMEEI RKRFEFGDNA EISIELDPRY LTDEQIKAIK DAGFNRISLG VQDLDPKVQQ 

       190        200        210        220        230        240 
AVNRVQPYEL IKEKMEKLRE AGFESINLDL IYGLPYQTKE SFEKTVEKVI ELNPDRIATY 

       250        260        270        280        290        300 
SFAYIPQVKP HQQLLPKEAL PSAEEKLRIF EMVINKFQEA GYVYIGMDHF AKPEDELAVA 

       310        320        330        340        350        360 
QRKGELWRNF QGYTTKKGVE LLGFGATSIG MLYDSYFQNW KTLRDYNKTV DEGKIPVFRG 

       370        380        390        400        410        420 
YVLNEDDFIR REVIMDIMCN LGVEFSKIEN MFGINFREYF AKELEELKEM EEDGLIKVEE 

       430        440        450 
DRIKIMPVGR LLIRNVAMVF DAHLRRKKEL NFSRTI
O67886 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA) 		Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Hosted by ca flag CBR Canada Mirror sites: Australia Brazil China Korea Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!