ID   DHE4_BOTFU              Reviewed;         450 AA.
AC   O93934;
DT   16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   25-NOV-2008, entry version 37.
DE   RecName: Full=NADP-specific glutamate dehydrogenase;
DE            Short=NADP-GDH;
DE            EC=1.4.1.4;
DE   AltName: Full=NADP-dependent glutamate dehydrogenase;
GN   Name=gdhA;
OS   Botryotinia fuckeliana (Noble rot fungus) (Botrytis cinerea).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Helotiales; Sclerotiniaceae; Botryotinia.
OX   NCBI_TaxID=40559;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=2850;
RA   Santos M.;
RT   "Cloning and regulation of the gdhA gene from Botrytis cinerea.";
RL   Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: L-glutamate + H(2)O + NADP(+) = 2-oxoglutarate
CC       + NH(3) + NADPH.
CC   -!- SUBUNIT: Homohexamer (By similarity).
CC   -!- SIMILARITY: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
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DR   EMBL; AF109684; AAC95390.1; -; Genomic_DNA.
DR   HSSP; P24295; 1AUP.
DR   GO; GO:0005488; F:binding; IEA:InterPro.
DR   GO; GO:0004354; F:glutamate dehydrogenase (NADP+) activity; IEA:EC.
DR   GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   InterPro; IPR006095; Glu/Leu/Phe/Val_DHase.
DR   InterPro; IPR006096; Glu/Leu/Phe/Val_DHase_C.
DR   InterPro; IPR006097; Glu/Leu/Phe/Val_DHase_dimer.
DR   InterPro; IPR014362; Glu_DHase.
DR   InterPro; IPR016040; NAD(P)-bd.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   PANTHER; PTHR11606:SF2; GLFV_DH; 1.
DR   Pfam; PF00208; ELFV_dehydrog; 1.
DR   Pfam; PF02812; ELFV_dehydrog_N; 1.
DR   PIRSF; PIRSF000185; Glu_DH; 1.
DR   PRINTS; PR00082; GLFDHDRGNASE.
DR   PROSITE; PS00074; GLFV_DEHYDROGENASE; 1.
PE   3: Inferred from homology;
KW   NADP; Oxidoreductase.
FT   CHAIN         1    450       NADP-specific glutamate dehydrogenase.
FT                                /FTId=PRO_0000182784.
FT   ACT_SITE    114    114       By similarity.
SQ   SEQUENCE   450 AA;  49044 MW;  6EDAFAB75B03C93A CRC64;
     MSNLPSEPEF EQAYNELAST LENSTLFEKN PEYRTALKVV SIPERVIQFR VVWEDDKNQV
     QVNRGYRVQF NSALGPYKGG LRFHPTVNLS VLKFLGFEQI FKNALTGLNI GGGKGGADFD
     PKGKSDNEIR RFCVSFMREL SKHIGADTDV PAGDINVGGR EIGFLFGAYK AIQNKWEGVL
     TGKGGSWGGS LIRPEATGYG LVYYVAHMIQ YAGQGSFQGK RVAISGSGNV AQYAALKCIE
     LGATVVSLSD SQGSLIAEGD AYFTPEDVGK IAELKLKRQS LTAFEHGGKY KYIEGSRPWT
     HVKVDVALPC ATQNEVSKEE AESLVASGAR YIAEGSNMGC TQEAIDVFEA ERKEKKDKAI
     WYAPGKAANA GGVAVSGLEM AQNSARISWT QEEVDEKLKD IMKNAFETGL ETPKKYVEAK
     DGEYPSLVAG SNIAGFVKVA SAMHNHGDWW
//