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UniProtKB/Swiss-Prot entry O94511


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name YN67_SCHPO
Primary accession number O94511
Secondary accession numbers None
Integrated into Swiss-Prot on February 5, 2008
Sequence was last modified on May 1, 1999 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 38)
Name and origin of the protein
Protein name Putative enoyl reductase C646.07c
Synonym EC 1.3.1.38
Gene name
ORFNames: SPBC646.07c
From
Schizosaccharomyces pombe (Fission yeast) [TaxID: 4896] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 38366 / 972;
DOI=10.1038/nature724; PubMed=11859360 [NCBI, ExPASy, EBI, Israel, Japan]
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M., Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.;
"The genome sequence of Schizosaccharomyces pombe.";
Nature 415:871-880(2002).
[2]
SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
DOI=10.1038/nbt1222; PubMed=16823372 [NCBI, ExPASy, EBI, Israel, Japan]
Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M.;
"ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.";
Nat. Biotechnol. 24:841-847(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CU329671; CAA22811.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR T40583; T40583.
RefSeq NP_595365.1; -.
3D structure databases
ModBase O94511.
Organism-specific databases
GeneDB_Spombe SPBC646.07c; -.
Gene expression databases
ArrayExpress O94511; -.
Ontologies
GO
GO:0005783; Cellular component: endoplasmic reticulum (inferred from direct assay from GeneDB_SPombe).
GO:0016631; Molecular function: enoyl-[acyl-carrier-protein] reductase activity (non-traceable author statement from GeneDB_SPombe).
GO:0030497; Biological process: fatty acid elongation (non-traceable author statement from GeneDB_SPombe).
QuickGo view.
Family and domain databases
InterPro IPR001104; 3-oxo-5_a-steroid_4-DHase_C.
Graphical view of domain structure.
Pfam PF02544; Steroid_dh; 1.
Pfam graphical view of domain structure.
PROSITE PS50244; S5A_REDUCTASE; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS O94511.
Genome annotation databases
GeneID 2541070; -.
KEGG spo:SPBC646.07c; -.
NMPDR fig|4896.1.peg.1231; -.
Other
ProtoNet O94511.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Endoplasmic reticulum; Lipid synthesis; Membrane; NADP; Oxidoreductase; Transmembrane.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   295  295     Putative enoyl reductase C646.07c. PRO_0000317698
TOPO_DOM   1    84  84     Cytoplasmic (Potential). 
TRANSMEM   85   105  21     Potential. 
TOPO_DOM   106   157  52     Lumenal (Potential). 
TRANSMEM   158   178  21     Potential. 
TOPO_DOM   179   186  8     Cytoplasmic (Potential). 
TRANSMEM   187   207  21     Potential. 
TOPO_DOM   208   223  16     Lumenal (Potential). 
TRANSMEM   224   246  23     Potential. 
TOPO_DOM   247   250  4     Cytoplasmic (Potential). 
TRANSMEM   251   268  18     Potential. 
TOPO_DOM   269   295  27     Lumenal (Potential). 
Sequence information
Length: 295 AA [This is the length of the unprocessed precursor] Molecular weight: 34640 Da [This is the MW of the unprocessed precursor] CRC64: B4181D13E0F3C333 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSITLSSRGR KIRKLPKSLE FPLDGSIDKL RDEVSSVTRL PVERLRFSTA DGTTLLPNTT 

        70         80         90        100        110        120 
LRKYGVGPGA TIWVKDLGPQ IGWRTVFMIE YLGPLVIHLF FILNYKWIYR KDYNLCLNQK 

       130        140        150        160        170        180 
IAFVLVMLHF MKREYESIFV HRFSLATMPL RNIFKNCAHY HLLSGLFLAY FIYGPWHAND 

       190        200        210        220        230        240 
YIKPNHLLFL IVGWAFAVLS NFRTHIILRD LRPAGSKKRV IPTGYGFNLV SFPNYFFESL 

       250        260        270        280        290 
GWLFFALLTK SWASWIFLFV GSAQMFVWAK KKHARYLKEF PNYPRSRKIM IPFFL 

O94511 in FASTA format

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