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[1]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA].
DOI=10.1038/308613a0; PubMed=6546784 [NCBI, ExPASy, EBI, Israel, Japan]
Chin D.J.,
Gil G.,
Russell D.W.,
Liscum L.,
Luskey K.L.,
Basu S.K.,
Okayama H.,
Berg P.,
Goldstein J.L.,
Brown M.S.;
"Nucleotide sequence of 3-hydroxy-3-methyl-glutaryl coenzyme A reductase, a glycoprotein of endoplasmic reticulum.";
Nature 308:613-617(1984).
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[2]
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GENE STRUCTURE.
DOI=10.1016/0092-8674(84)90549-X; PubMed=6088070 [NCBI, ExPASy, EBI, Israel, Japan]
Reynolds G.A.,
Basu S.K.,
Osborne T.F.,
Chin D.J.,
Gil G.,
Brown M.S.,
Goldstein J.L.,
Luskey K.L.;
"HMG CoA reductase: a negatively regulated gene with unusual promoter and 5' untranslated regions.";
Cell 38:275-285(1984).
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[3]
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DOMAINS.
PubMed=3965461 [NCBI, ExPASy, EBI, Israel, Japan]
Liscum L.,
Finer-Moore J.,
Stroud R.M.,
Luskey K.L.,
Brown M.S.,
Goldstein J.L.;
"Domain structure of 3-hydroxy-3-methylglutaryl coenzyme A reductase, a glycoprotein of the endoplasmic reticulum.";
J. Biol. Chem. 260:522-530(1985).
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Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms.
Distributed under the Creative Commons Attribution-NoDerivs License.
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| Length: 887 AA [This is the length of the unprocessed precursor] |
Molecular weight: 97081 Da [This is the MW of the unprocessed precursor] |
CRC64: 4331E53ADA250E6A [This is a checksum on the sequence] |
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10 20 30 40 50 60
MLSRLFRMHG LFVASHPWEV IVGTVTLTIC MMSMNMFTGN NKICGWNYEC PKFEEDVLSS
70 80 90 100 110 120
DIIILTITRC IAILYIYFQF QNLRQLGSKY ILGIAGLFTI FSSFVFSTVV IHFLDKELTG
130 140 150 160 170 180
LNEALPFFLL LIDLSRASAL AKFALSSNSQ DEVRENIARG MAILGPTFTL DALVECLVIG
190 200 210 220 230 240
VGTMSGVRQL EIMCCFGCMS VLANYFVFMT FFPACVSLVL ELSRESREGR PIWQLSHFAR
250 260 270 280 290 300
VLEEEENKPN PVTQRVKMIM SLGLVLVHAH SRWIADPSPQ NSTTEHSKVS LGLDEDVSKR
310 320 330 340 350 360
IEPSVSLWQF YLSKMISMDI EQVVTLSLAF LLAVKYIFFE QAETESTLSL KNPITSPVVT
370 380 390 400 410 420
PKKAPDNCCR REPLLVRRSE KLSSVEEEPG VSQDRKVEVI KPLVVETESA SRATFVLGAS
430 440 450 460 470 480
GTSPPVAART QELEIELPSE PRPNEECLQI LESAEKGAKF LSDAEIIQLV NAKHIPAYKL
490 500 510 520 530 540
ETLMETHERG VSIRRQLLST KLPEPSSLQY LPYRDYNYSL VMGACCENVI GYMPIPVGVA
550 560 570 580 590 600
GPLCLDGKEY QVPMATTEGC LVASTNRGCR AIGLGGGASS RVLADGMTRG PVVRLPRACD
610 620 630 640 650 660
SAEVKAWLET PEGFAVIKDA FDSTSRFARL QKLHVTMAGR NLYIRFQSKT GDAMGMNMIS
670 680 690 700 710 720
KGTEKALLKL QEFFPEMQIL AVSGNYCTDK KPAAINWIEG RGKTVVCEAV IPAKVVREVL
730 740 750 760 770 780
KTTTEAMIDV NINKNLVGSA MAGSIGGYNA HAANIVTAIY IACGQDAAQN VGSSNCITLM
790 800 810 820 830 840
EASGPTNEDL YISCTMPSIE IGTVGGGTNL LPQQACLQML GVQGACKDNP GENARQLARI
850 860 870 880
VCGTVMAGEL SLMAALAAGH LVRSHMVHNR SKINLQDLQG TCTKKSA
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P00347 in FASTA format |
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