[1]
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NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Fibroblast;
DOI=10.1016/0006-291X(87)90921-1; PubMed=3120710 [NCBI, ExPASy, EBI, Israel, Japan]
Uchida K.,
Morita T.,
Sato T.,
Ogura T.,
Yamashita R.,
Noguchi S.,
Suzuki H.,
Nyunoya H.,
Miwa M.,
Sugimura T.;
"Nucleotide sequence of a full-length cDNA for human fibroblast poly(ADP-ribose) polymerase.";
Biochem. Biophys. Res. Commun. 148:617-622(1987).
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[2]
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NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Fibroblast;
PubMed=2824474 [NCBI, ExPASy, EBI, Israel, Japan]
Kurosaki T.,
Ushiro H.,
Mitsuuchi Y.,
Suzuki S.,
Matsuda M.,
Matsuda Y.,
Katunuma N.,
Kangawa K.,
Matsuo H.,
Hirose T.,
Inayama S.,
Shizuta Y.;
"Primary structure of human poly(ADP-ribose) synthetase as deduced from cDNA sequence.";
J. Biol. Chem. 262:15990-15997(1987).
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[3]
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NUCLEOTIDE SEQUENCE [MRNA], AND VARIANT ARG-940.
DOI=10.1073/pnas.84.23.8370; PubMed=2891139 [NCBI, ExPASy, EBI, Israel, Japan]
Cherney B.W.,
McBride O.W.,
Chen D.,
Alkhatib H.,
Bhatia K.,
Hensley P.,
Smulson M.E.;
"cDNA sequence, protein structure, and chromosomal location of the human gene for poly(ADP-ribose) polymerase.";
Proc. Natl. Acad. Sci. U.S.A. 84:8370-8374(1987).
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[4]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA].
PubMed=2513174 [NCBI, ExPASy, EBI, Israel, Japan]
Auer B.,
Nagl U.,
Herzog H.,
Schneider R.,
Schweiger M.;
"Human nuclear NAD+ ADP-ribosyltransferase(polymerizing): organization of the gene.";
DNA 8:575-580(1989).
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[5]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND VARIANTS THR-188; ILE-334; TYR-383; ALA-762 AND ARG-940.
NIEHS SNPs program;
Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases.
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[6]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], AND VARIANT ALA-762.
TISSUE=Brain;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
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[7]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-95.
DOI=10.1111/j.1432-1033.1990.tb15647.x; PubMed=2125269 [NCBI, ExPASy, EBI, Israel, Japan]
Yokoyama Y.,
Kawamoto T.,
Mitsuuchi Y.,
Kurosaki T.,
Toda K.,
Ushiro H.,
Terashima M.,
Sumimoto H.,
Kuribayashi I.,
Yamamoto Y.,
Maeda T.,
Ikeda H.,
Sagara Y.,
Shizuta Y.;
"Human poly(ADP-ribose) polymerase gene. Cloning of the promoter region.";
Eur. J. Biochem. 194:521-526(1990).
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[8]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-40.
DOI=10.1016/0006-291X(90)92082-B; PubMed=2108670 [NCBI, ExPASy, EBI, Israel, Japan]
Ogura T.,
Nyunoya H.,
Takahashi-Masutani M.,
Miwa M.,
Sugimura T.,
Esumi H.;
"Characterization of a putative promoter region of the human poly(ADP-ribose) polymerase gene: structural similarity to that of the DNA polymerase beta gene.";
Biochem. Biophys. Res. Commun. 167:701-710(1990).
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[9]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-40.
Herzog H.,
Schneider R.,
Hirsch-Kauffmann M.,
Schnitzer D.,
Schweiger M.;
"Human pADPRT is involved in the regulation of its own gene.";
Submitted (JUL-1991) to the EMBL/GenBank/DDBJ databases.
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[10]
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PROTEIN SEQUENCE OF 2-10; 35-47; 66-78; 109-119; 183-197; 209-221; 263-282; 453-467; 487-496; 529-548; 552-564; 572-582; 637-654; 668-695; 748-761; 780-796; 803-816 AND 859-903, CLEAVAGE OF INITIATOR METHIONINE, ACETYLATION AT ALA-2, AND MASS SPECTROMETRY.
TISSUE=Colon carcinoma, and Ovarian carcinoma;
Bienvenut W.V.,
Zebisch A.,
Lilla S.,
von Kriegsheim A.,
Lempens A.,
Kolch W.;
Submitted (DEC-2008) to UniProtKB.
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[11]
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NUCLEOTIDE SEQUENCE [MRNA] OF 381-420 AND 682-710.
PubMed=3121332 [NCBI, ExPASy, EBI, Israel, Japan]
Schneider R.,
Auer B.,
Kuhne C.,
Herzog H.,
Klocker H.,
Burtscher H.J.,
Hirsch-Kauffmann M.,
Wintersberger U.,
Schweiger M.;
"Isolation of a cDNA clone for human NAD+: protein ADP-ribosyltransferase.";
Eur. J. Cell Biol. 44:302-307(1987).
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[12]
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NUCLEOTIDE SEQUENCE [MRNA] OF 441-1014.
DOI=10.1016/0006-291X(87)90543-2; PubMed=3113420 [NCBI, ExPASy, EBI, Israel, Japan]
Suzuki H.,
Uchida K.,
Shima H.,
Sato T.,
Okamoto T.,
Kimura T.,
Miwa M.;
"Molecular cloning of cDNA for human poly(ADP-ribose) polymerase and expression of its gene during HL-60 cell differentiation.";
Biochem. Biophys. Res. Commun. 146:403-409(1987).
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[13]
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ERRATUM.
Suzuki H.,
Uchida K.,
Shima H.,
Sato T.,
Okamoto T.,
Kimura T.,
Miwa M.;
Biochem. Biophys. Res. Commun. 148:1549-1550(1987).
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[14]
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ANALYSIS OF ZINC FINGERS.
DOI=10.1073/pnas.87.8.2990; PubMed=2109322 [NCBI, ExPASy, EBI, Israel, Japan]
Gradwohl G.,
Menissier-de Murcia J.,
Molinete M.,
Simonin F.,
Koken M.H.M.,
Hoeijmakers J.H.J.,
de Murcia G.M.;
"The second zinc-finger domain of poly(ADP-ribose) polymerase determines specificity for single-stranded breaks in DNA.";
Proc. Natl. Acad. Sci. U.S.A. 87:2990-2994(1990).
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[15]
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ANALYSIS OF ZINC FINGERS.
PubMed=2123876 [NCBI, ExPASy, EBI, Israel, Japan]
Ikelima M.,
Noguchi S.,
Yamashita R.,
Ogura T.,
Sugimura T.,
Gill D.M.,
Miwa M.;
"The zinc fingers of human poly(ADP-ribose) polymerase are differentially required for the recognition of DNA breaks and nicks and the consequent enzyme activation. Other structures recognize intact DNA.";
J. Biol. Chem. 265:21907-21913(1990).
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[16]
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MUTAGENESIS OF CATALYTIC DOMAIN.
PubMed=2121735 [NCBI, ExPASy, EBI, Israel, Japan]
Simonin F.,
Menissier-de Murcia J.,
Poch O.,
Muller S.,
Gradwohl G.,
Molinete M.,
Penning C.,
Keith G.,
de Murcia G.M.;
"Expression and site-directed mutagenesis of the catalytic domain of human poly(ADP-ribose)polymerase in Escherichia coli. Lysine 893 is critical for activity.";
J. Biol. Chem. 265:19249-19256(1990).
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[17]
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NUCLEAR LOCALIZATION SIGNAL.
PubMed=1505517 [NCBI, ExPASy, EBI, Israel, Japan]
Schreiber V.,
Molinete M.,
Boeuf H.,
de Murcia G.M.,
Menissier-de Murcia J.;
"The human poly(ADP-ribose) polymerase nuclear localization signal is a bipartite element functionally separate from DNA binding and catalytic activity.";
EMBO J. 11:3263-3269(1992).
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[18]
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MUTAGENESIS OF CATALYTIC DOMAIN.
DOI=10.1021/bi971055p; PubMed=9315851 [NCBI, ExPASy, EBI, Israel, Japan]
Rolli V.,
O'Farrell M.,
Menissier-de Murcia J.,
de Murcia G.M.;
"Random mutagenesis of the poly(ADP-ribose) polymerase catalytic domain reveals amino acids involved in polymer branching.";
Biochemistry 36:12147-12154(1997).
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[19]
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PHOSPHORYLATION.
DOI=10.1038/sj.onc.1202823; PubMed=10467406 [NCBI, ExPASy, EBI, Israel, Japan]
Ariumi Y.,
Masutani M.,
Copeland T.D.,
Mimori T.,
Sugimura T.,
Shimotohno K.,
Ueda K.,
Hatanaka M.,
Noda M.;
"Suppression of the poly(ADP-ribose) polymerase activity by DNA-dependent protein kinase in vitro.";
Oncogene 18:4616-4625(1999).
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[20]
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INTERACTION WITH APTX.
DOI=10.1093/hmg/ddh122; PubMed=15044383 [NCBI, ExPASy, EBI, Israel, Japan]
Gueven N.,
Becherel O.J.,
Kijas A.W.,
Chen P.,
Howe O.,
Rudolph J.H.,
Gatti R.,
Date H.,
Onodera O.,
Taucher-Scholz G.,
Lavin M.F.;
"Aprataxin, a novel protein that protects against genotoxic stress.";
Hum. Mol. Genet. 13:1081-1093(2004).
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[21]
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INTERACTION WITH SRY.
DOI=10.1016/j.mce.2006.06.008; PubMed=16904257 [NCBI, ExPASy, EBI, Israel, Japan]
Li Y.,
Oh H.J.,
Lau Y.-F.C.;
"The poly(ADP-ribose) polymerase 1 interacts with Sry and modulates its biological functions.";
Mol. Cell. Endocrinol. 257:35-46(2006).
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[22]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-179, AND MASS SPECTROMETRY.
DOI=10.1126/science.1140321; PubMed=17525332 [NCBI, ExPASy, EBI, Israel, Japan]
Matsuoka S.,
Ballif B.A.,
Smogorzewska A.,
McDonald E.R. III,
Hurov K.E.,
Luo J.,
Bakalarski C.E.,
Zhao Z.,
Solimini N.,
Lerenthal Y.,
Shiloh Y.,
Gygi S.P.,
Elledge S.J.;
"ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.";
Science 316:1160-1166(2007).
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[23]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-41; THR-368 AND SER-782, AND MASS SPECTROMETRY.
DOI=10.1073/pnas.0805139105; PubMed=18669648 [NCBI, ExPASy, EBI, Israel, Japan]
Dephoure N.,
Zhou C.,
Villen J.,
Beausoleil S.A.,
Bakalarski C.E.,
Elledge S.J.,
Gygi S.P.;
"A quantitative atlas of mitotic phosphorylation.";
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
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[24]
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IDENTIFICATION [LARGE SCALE ANALYSIS], AND MASS SPECTROMETRY.
Colinge J.,
Superti-Furga G.,
Bennett K.L.;
Submitted (OCT-2008) to UniProtKB.
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[25]
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STRUCTURE BY NMR OF 1-93 AND 385-643.
RIKEN structural genomics initiative (RSGI);
"Solution structure of the first ZF-PARP domain, of the BRCT domain and of the WGR domain of human poly(adp-ribose)polymerase-1.";
Submitted (APR-2007) to the PDB data bank.
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[26]
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VARIANT [LARGE SCALE ANALYSIS] VAL-488.
DOI=10.1126/science.1133427; PubMed=16959974 [NCBI, ExPASy, EBI, Israel, Japan]
Sjoeblom T.,
Jones S.,
Wood L.D.,
Parsons D.W.,
Lin J.,
Barber T.D.,
Mandelker D.,
Leary R.J.,
Ptak J.,
Silliman N.,
Szabo S.,
Buckhaults P.,
Farrell C.,
Meeh P.,
Markowitz S.D.,
Willis J.,
Dawson D.,
Willson J.K.V.,
Gazdar A.F., ![]()
Hartigan J.,
Wu L.,
Liu C.,
Parmigiani G.,
Park B.H.,
Bachman K.E.,
Papadopoulos N.,
Vogelstein B.,
Kinzler K.W.,
Velculescu V.E.;
"The consensus coding sequences of human breast and colorectal cancers.";
Science 314:268-274(2006).
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