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[1]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1016/S0140-6736(00)04403-2; PubMed=11418146 [NCBI, ExPASy, EBI, Israel, Japan]
Kuroda M.,
Ohta T.,
Uchiyama I.,
Baba T.,
Yuzawa H.,
Kobayashi I.,
Cui L.,
Oguchi A.,
Aoki K.,
Nagai Y.,
Lian J.-Q.,
Ito T.,
Kanamori M.,
Matsumaru H.,
Maruyama A.,
Murakami H.,
Hosoyama A.,
Mizutani-Ui Y.,
Takahashi N.K., ![]()
Sawano T.,
Inoue R.,
Kaito C.,
Sekimizu K.,
Hirakawa H.,
Kuhara S.,
Goto S.,
Yabuzaki J.,
Kanehisa M.,
Yamashita A.,
Oshima K.,
Furuya K.,
Yoshino C.,
Shiba T.,
Hattori M.,
Ogasawara N.,
Hayashi H.,
Hiramatsu K.;
"Whole genome sequencing of meticillin-resistant Staphylococcus aureus.";
Lancet 357:1225-1240(2001).
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- FUNCTION: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
- CATALYTIC ACTIVITY: Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2.
- COFACTOR: Thiamine pyrophosphate (By similarity).
- SUBUNIT: Heterodimer of an alpha and a beta chain.
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Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms.
Distributed under the Creative Commons Attribution-NoDerivs License.
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| Length: 325 AA [This is the length of the unprocessed precursor] |
Molecular weight: 35246 Da [This is the MW of the unprocessed precursor] |
CRC64: 432ABDF6E4A720D5 [This is a checksum on the sequence] |
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10 20 30 40 50 60
MAQMTMVQAI NDALKTELKN DQDVLIFGED VGVNGGVFRV TEGLQKEFGE DRVFDTPLAE
70 80 90 100 110 120
SGIGGLAMGL AVEGFRPVME VQFLGFVFEV FDAIAGQIAR TRFRSGGTKT APVTIRSPFG
130 140 150 160 170 180
GGVHTPELHA DNLEGILAQS PGLKVVIPSG PYDAKGLLIS SIRSNDPVVY LEHMKLYRSF
190 200 210 220 230 240
REEVPEEEYT IDIGKANVKK EGNDISIITY GAMVQESMKA AEELEKDGYS VEVIDLRTVQ
250 260 270 280 290 300
PIDVDTIVAS VEKTGRAVVV QEAQRQAGVG AAVVAELSER AILSLEAPIG RVAAADTIYP
310 320
FTQAENVWLP NKNDIIEKAK ETLEF
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P0A0A1 in FASTA format |
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