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[1]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
DOI=10.1038/35054089; PubMed=11206551 [NCBI, ExPASy, EBI, Israel, Japan]
Perna N.T.,
Plunkett G. III,
Burland V.,
Mau B.,
Glasner J.D.,
Rose D.J.,
Mayhew G.F.,
Evans P.S.,
Gregor J.,
Kirkpatrick H.A.,
Posfai G.,
Hackett J.,
Klink S.,
Boutin A.,
Shao Y.,
Miller L.,
Grotbeck E.J.,
Davis N.W.,
Lim A., ![]()
Dimalanta E.T.,
Potamousis K.,
Apodaca J.,
Anantharaman T.S.,
Lin J.,
Yen G.,
Schwartz D.C.,
Welch R.A.,
Blattner F.R.;
"Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
Nature 409:529-533(2001).
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[2]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
DOI=10.1093/dnares/8.1.11; PubMed=11258796 [NCBI, ExPASy, EBI, Israel, Japan]
Hayashi T.,
Makino K.,
Ohnishi M.,
Kurokawa K.,
Ishii K.,
Yokoyama K.,
Han C.-G.,
Ohtsubo E.,
Nakayama K.,
Murata T.,
Tanaka M.,
Tobe T.,
Iida T.,
Takami H.,
Honda T.,
Sasakawa C.,
Ogasawara N.,
Yasunaga T.,
Kuhara S., ![]()
Shiba T.,
Hattori M.,
Shinagawa H.;
"Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and genomic comparison with a laboratory strain K-12.";
DNA Res. 8:11-22(2001).
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- FUNCTION: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
- CATALYTIC ACTIVITY: Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2.
- COFACTOR: Magnesium (By similarity).
- COFACTOR: Thiamine pyrophosphate (By similarity).
- SUBUNIT: Homodimer (By similarity).
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Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms.
Distributed under the Creative Commons Attribution-NoDerivs License.
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| Length: 887 AA [This is the length of the unprocessed precursor] |
Molecular weight: 99668 Da [This is the MW of the unprocessed precursor] |
CRC64: 7FB3811DE11BDD02 [This is a checksum on the sequence] |
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10 20 30 40 50 60
MSERFPNDVD PIETRDWLQA IESVIREEGV ERAQYLIDQL LAEARKGGVN VAAGTGISNY
70 80 90 100 110 120
INTIPVEEQP EYPGNLELER RIRSAIRWNA IMTVLRASKK DLELGGHMAS FQSSATIYDV
130 140 150 160 170 180
CFNHFFRARN EQDGGDLVYF QGHISPGVYA RAFLEGRLTQ EQLDNFRQEV HGNGLSSYPH
190 200 210 220 230 240
PKLMPEFWQF PTVSMGLGPI GAIYQAKFLK YLEHRGLKDT SKQTVYAFLG DGEMDEPESK
250 260 270 280 290 300
GAITIATREK LDNLVFVINC NLQRLDGPVT GNGKIINELE GIFEGAGWNV IKVMWGSRWD
310 320 330 340 350 360
ELLRKDTSGK LIQLMNETVD GDYQTFKSKD GAYVREHFFG KYPETAALVA DWTDEQIWAL
370 380 390 400 410 420
NRGGHDPKKI YAAFKKAQET KGKATVILAH TIKGYGMGDA AEGKNIAHQV KKMNMDGVRH
430 440 450 460 470 480
IRDRFNVPVS DADIEKLPYI TFPEGSEEHT YLHAQRQKLH GYLPSRQPNF TEKLELPSLQ
490 500 510 520 530 540
DFGALLEEQS KEISTTIAFV RALNVMLKNK SIKDRLVPII ADEARTFGME GLFRQIGIYS
550 560 570 580 590 600
PNGQQYTPQD REQVAYYKED EKGQILQEGI NELGAGCSWL AAATSYSTNN LPMIPFYIYY
610 620 630 640 650 660
SMFGFQRIGD LCWAAGDQQA RGFLIGGTSG RTTLNGEGLQ HEDGHSHIQS LTIPNCISYD
670 680 690 700 710 720
PAYAYEVAVI MHDGLERMYG EKQENVYYYI TTLNENYHMP AMPEGAEEGI RKGIYKLETI
730 740 750 760 770 780
EGSKGKVQLL GSGSILRHVR EAAEILAKDY GVGSDVYSVT SFTELARDGQ DCERWNMLHP
790 800 810 820 830 840
LETPRVPYIA QVMNDAPAVA STDYMKLFAE QVRTYVPADD YRVLGTDGFG RSDSRENLRH
850 860 870 880
HFEVDASYVV VAALGELAKR GEIDKKVVAD AIAKFNIDAD KVNPRLA
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P0AFG9 in FASTA format |
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