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UniProtKB/Swiss-Prot entry P0C601

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ODO1_STAAU
Primary accession number P0C601
Secondary accession numbers Q7ASB7 Q7WRM3 Q7WRN1 Q7WRX0 Q7WZ40
Integrated into Swiss-Prot on January 15, 2008
Sequence was last modified on January 15, 2008 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 5)
Name and origin of the protein
Protein name 2-oxoglutarate dehydrogenase E1 component
Synonyms EC 1.2.4.2
Alpha-ketoglutarate dehydrogenase
Gene name
Name: odhA
From
Staphylococcus aureus [TaxID: 1280] 
Taxonomy Bacteria; Firmicutes; Bacillales; Staphylococcus.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=FranceDuf, Glasgow3700, Glasgow3759, LIM1, LIM2, LIM3, LiverpoolAG, LLA, LLE, Michigan, New Jersey, Norway1018, PC1, PC3, Slovenia6096, SMH10501, SMH11888, SMH12248, SMH14017, SMH17487, SMH17608, SMH18000, SMH18034, SMH18037, SMH2, SMH8997, Southampton23, St. Luke, Sweden307, and Sweden309;
Wootton M., Avison M.B., Bennett P.M., Howe R.A., MacGowan A.P., Walsh T.R.;
"Genetic analysis of seventeen genes in Staphylococcus aureus with reduced susceptibility to vancomycin (VRSA) and hetero-VRSA (hVRSA).";
Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AJ564531; CAD92198.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AJ564532; CAD92199.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AJ564533; CAD92200.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AJ564534; CAD92201.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AJ564535; CAD92202.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AJ564536; CAD92203.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AJ564537; CAD92204.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AJ564538; CAD92205.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AJ564539; CAD92206.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AJ564540; CAD92207.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AJ564541; CAD92208.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AJ564542; CAD92209.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AJ564543; CAD92210.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AJ564544; CAD92211.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AJ564545; CAD92212.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AJ564546; CAD92213.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AJ564547; CAD92214.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AJ564548; CAD92215.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AJ564549; CAD92216.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AJ564550; CAD92217.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AJ564551; CAD92218.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AJ564552; CAD92219.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AJ564553; CAD92220.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AJ564554; CAD92221.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AJ564555; CAD92222.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AJ564556; CAD92223.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AJ564557; CAD92224.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AJ564558; CAD92225.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AJ564559; CAD92226.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AJ564560; CAD92227.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AJ564561; CAD92228.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
3D structure databases
ModBase P0C601.
Ontologies
GO
GO:0004591; Molecular function: oxoglutarate dehydrogenase (succinyl-transferring) activity (inferred from electronic annotation from HAMAP).
GO:0030976; Molecular function: thiamin pyrophosphate binding (inferred from electronic annotation from HAMAP).
GO:0006096; Biological process: glycolysis (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01169; -; 1.
PBIL [Tree]
InterPro IPR011603; 2oxoglutarate_DHase_E1.
IPR001017; DHase_E1.
IPR005475; Transketo_Cen_R.
Graphical view of domain structure.
PANTHER PTHR23152; 2oxoglutarate_DH_E1; 1.
Pfam PF00676; E1_dh; 1.
PF02779; Transket_pyr; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000157; Oxoglu_dh_E1; 1.
TIGRFAMs TIGR00239; 2oxo_dh_E1; 1.
BLOCKS P0C601.
Other
ProtoNet P0C601.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Glycolysis; Oxidoreductase; Thiamine pyrophosphate.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   932  932     2-oxoglutarate dehydrogenase E1 component. PRO_0000224241
VARIANT   46    67  22     Missing (in strain: SMH8997, LLA, LLE, SMH10501, SMH11888, SMH12248, SMH14017, SMH17487, SMH17608, SMH18000, SMH18034 and SMH18037). 
VARIANT   534   534  1     E -> D (in strain: 23, 3700, 3759, LIM1, LIM2 and LIM3). 
VARIANT   864   864  1     K -> N (in strain: 23, 3700, 3759, LIM1, LIM2 and LIM3). 
Sequence information
Length: 932 AA [This is the length of the unprocessed precursor] Molecular weight: 105383 Da [This is the MW of the unprocessed precursor] CRC64: C744C1868AE20A38 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MTNERKEVSE APVNFGANLG LMLDLYDDFL QDPSSVPEDL QVLFSIIKND DSIVPALKST 

        70         80         90        100        110        120 
SSQNSDGTIK RVMRLIDNIR QYGHLKADIY PVNPPKRKHV PKLEIEDFDL DQQTLEGISA 

       130        140        150        160        170        180 
GIVSDHFADI YDNAYEAILR MEKRYKGPIA FEYTHINNNT ERGWLKRRIE TPYKVTLNNN 

       190        200        210        220        230        240 
EKRALFKQLA YVEGFEKYLH KNFVGAKRFS IEGVDALVPM LQRTITIAAK EGIKNIQIGM 

       250        260        270        280        290        300 
AHRGRLNVLT HVLEKPYEMM ISEFMHTDPM KFLPEDGSLQ LTAGWTGDVK YHLGGIKTTD 

       310        320        330        340        350        360 
SYGTMQRIAL ANNPSHLEIV APVVEGRTRA AQDDTQRAGA PTTDHHKAMP IIIHGDAAYP 

       370        380        390        400        410        420 
GQGINFETMN LGNLKGYSTG GSLHIITNNR IGFTTEPIDA RSTTYSTDVA KGYDVPIFHV 

       430        440        450        460        470        480 
NADDVEATIE AIDIAMEFRK EFHKDVVIDL VGYRRFGHNE MDEPSITNPV PYQNIRKHDS 

       490        500        510        520        530        540 
VEYVFGKKLV NEGVISEDEM HSFIEQVQKE LRQAHDKINK ADKMDNPDME KPAELALPLQ 

       550        560        570        580        590        600 
ADEQSFTFDH LKEINDALLT YPDGFNILKK LNKVLEKRHE PFNKEDGLVD WAQAEQLAFA 

       610        620        630        640        650        660 
TILQDGTPIR LTGQDSERGT FSHRHAVLHD EQTGETYTPL HHVPDQKATF DIHNSPLSEA 

       670        680        690        700        710        720 
AVVGFEYGYN VENKKSFNIW EAQYGDFANM SQMIFDNFLF SSRSKWGERS GLTLFLPHAY 

       730        740        750        760        770        780 
EGQGPEHSSA RLERFLQLAA ENNCTVVNLS SSSNYFHLLR AQAASLDSEQ MRPLVVMSPK 

       790        800        810        820        830        840 
SLLRNKTVAK PIDEFTSGGF EPILTESYQA DKVTKVILAT GKMFIDLKEA LAKNPDESVL 

       850        860        870        880        890        900 
LVAIERLYPF PEEEIEALLA QLPKLEEVSW VQEEPKNQGA WLYVYPYVKV LVADKYDLSY 

       910        920        930 
HGRIQRAAPA EGDGEIHKLV QNKIIENALK NN
P0C601 in FASTA format

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View entry in raw text format (no links)
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