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UniProtKB/Swiss-Prot entry P12310


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name DHG_BACSU
Primary accession number P12310
Secondary accession number P94430
Integrated into Swiss-Prot on October 1, 1989
Sequence was last modified on May 30, 2000 (Sequence version 2)
Annotations were last modified on    September 2, 2008 (Entry version 67)
Name and origin of the protein
Protein name Glucose 1-dehydrogenase
Synonym EC 1.1.1.47
Gene name
Name: gdh
OrderedLocusNames: BSU03930
From
Bacillus subtilis [TaxID: 1423] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
PubMed=3082854 [NCBI, ExPASy, EBI, Israel, Japan]
Lampel K.A., Uratani B., Chaudhry G.R., Ramaley R.F., Rudikoff S.;
"Characterization of the developmentally regulated Bacillus subtilis glucose dehydrogenase gene.";
J. Bacteriol. 166:238-243(1986).
[2]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=168;
PubMed=8969502 [NCBI, ExPASy, EBI, Israel, Japan]
Yamane K., Kumano M., Kurita K.;
"The 25 degrees-36 degrees region of the Bacillus subtilis chromosome: determination of the sequence of a 146 kb segment and identification of 113 genes.";
Microbiology 142:3047-3056(1996).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=168;
DOI=10.1038/36786; PubMed=9384377 [NCBI, ExPASy, EBI, Israel, Japan]
Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.;
"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.";
Nature 390:249-256(1997).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
M12276; AAA22463.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
D50453; BAA09024.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
Z99106; CAB12201.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR D69629; D69629.
RefSeq NP_388275.1; -.
3D structure databases
HSSP P40288; 1GCO. [HSSP ENTRY / PDB]
SMR P12310; 1-261.
ModBase P12310.
Enzyme and pathway databases
BioCyc BSUB224308:BSU0394-MON; -.
Organism-specific databases
SubtiList BG10545; gdh. [Micado]
Family and domain databases
InterPro IPR002198; DHase_sc/Rdtase_SDR.
IPR002347; Glc/ribitol_DHase.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR19410; ADH_short_C2; 1.
Pfam PF00106; adh_short; 1.
Pfam graphical view of domain structure.
PRINTS PR00081; GDHRDH.
PR00080; SDRFAMILY.
PROSITE PS00061; ADH_SHORT; 1.
BLOCKS P12310.
Genome annotation databases
GeneID 938261; -.
GenomeReviews AL009126_GR; BSU03930.
KEGG bsu:BSU03930; -.
NMPDR fig|224308.1.peg.394; -.
Phylogenomic databases
HOGENOM P12310; -.
Genome annotation databases
CMR P12310; BSU03930.
Other
ProtoNet P12310.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; NADP; Oxidoreductase; Sporulation.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   261  261     Glucose 1-dehydrogenase. PRO_0000054616
NP_BIND   11    35  25     NADP (By similarity). 
ACT_SITE   158   158        Proton acceptor (By similarity). 
BINDING   145   145        Substrate (By similarity). 
CONFLICT   148   150        EVI -> AF (in Ref. 1; AAA22463). 
Sequence information
Length: 261 AA [This is the length of the unprocessed precursor] Molecular weight: 28090 Da [This is the MW of the unprocessed precursor] CRC64: 5894C17DB8F14965 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MYPDLKGKVV AITGAASGLG KAMAIRFGKE QAKVVINYYS NKQDPNEVKE EVIKAGGEAV 

        70         80         90        100        110        120 
VVQGDVTKEE DVKNIVQTAI KEFGTLDIMI NNAGLENPVP SHEMPLKDWD KVIGTNLTGA 

       130        140        150        160        170        180 
FLGSREAIKY FVENDIKGNV INMSSVHEVI PWPLFVHYAA SKGGIKLMTE TLALEYAPKG 

       190        200        210        220        230        240 
IRVNNIGPGA INTPINAEKF ADPKQKADVE SMIPMGYIGE PEEIAAVAAW LASKEASYVT 

       250        260 
GITLFADGGM TQYPSFQAGR G 

P12310 in FASTA format

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