ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry P13006


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name GOX_ASPNG
Primary accession number P13006
Secondary accession numbers None
Integrated into Swiss-Prot on January 1, 1990
Sequence was last modified on January 1, 1990 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 72)
Name and origin of the protein
Protein name Glucose oxidase [Precursor]
Synonyms EC 1.1.3.4
Glucose oxyhydrase
GOD
Beta-D-glucose:oxygen 1-oxido-reductase
Gene name
Name: gox
From
Aspergillus niger [TaxID: 5061] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Trichocomaceae; mitosporic Trichocomaceae; Aspergillus.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PARTIAL PROTEIN SEQUENCE.
STRAIN=ATCC 9029 / NRRL 3 / CBS 120.49 / DSM 2466 / N400;
DOI=10.1016/0014-5793(89)81061-0; PubMed=2792372 [NCBI, ExPASy, EBI, Israel, Japan]
Kriechbaum M., Heilmann H.J., Wientjes F.J., Hahn M., Jany K.-D., Gassen H.G., Sharif F., Alaeddinoglu G.;
"Cloning and DNA sequence analysis of the glucose oxidase gene from Aspergillus niger NRRL-3.";
FEBS Lett. 255:63-66(1989).
[2]
NUCLEOTIDE SEQUENCE [MRNA].
PubMed=2406261 [NCBI, ExPASy, EBI, Israel, Japan]
Frederick K.R., Tung J., Emerick R.S., Masiarz F.R., Chamberlain S.H., Vasavada A., Rosenberg S., Chakraborty S., Schopter L.M., Massey V.;
"Glucose oxidase from Aspergillus niger. Cloning, gene sequence, secretion from Saccharomyces cerevisiae and kinetic analysis of a yeast-derived enzyme.";
J. Biol. Chem. 265:3793-3802(1990).
[3]
NUCLEOTIDE SEQUENCE OF 1-32.
DOI=10.1007/BF00327024; PubMed=2076553 [NCBI, ExPASy, EBI, Israel, Japan]
Whittington H., Kerry-Williams S., Bidgood K., Dodsworth N., Peberdy J., Dobson M., Hinchliffe E., Ballance D.J.;
"Expression of the Aspergillus niger glucose oxidase gene in A. niger, A. nidulans and Saccharomyces cerevisiae.";
Curr. Genet. 18:531-536(1990).
[4]
X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS).
DOI=10.1006/jmbi.1993.1015; PubMed=8421298 [NCBI, ExPASy, EBI, Israel, Japan]
Hecht H.-J., Kalisz H.M., Hendle J., Schmid R.D., Schomburg D.;
"Crystal structure of glucose oxidase from Aspergillus niger refined at 2.3-A resolution.";
J. Mol. Biol. 229:153-172(1993).
[5]
X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS).
DOI=10.1107/S0907444999003431; PubMed=10216293 [NCBI, ExPASy, EBI, Israel, Japan]
Wohlfahrt G., Witt S., Hendle J., Schomburg D., Kalisz H.M., Hecht H.-J.;
"1.8 and 1.9-A resolution structures of the Penicillium amagasakiense and Aspergillus niger glucose oxidases as a basis for modelling substrate complexes.";
Acta Crystallogr. D 55:969-977(1999).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
X16061; CAA34197.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
J05242; AAA32695.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
X56443; CAA39826.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR A35459; A35459.
3D structure databases
PDB
1CF3; X-ray; 1.90 A; A=23-605.[ExPASy / RCSB / EBI]
1GAL; X-ray; 2.30 A; A=23-605.[ExPASy / RCSB / EBI]
Detailed list of linked structures.
PDBsum 1CF3; -.
1GAL; -.
ModBase P13006.
Family and domain databases
InterPro IPR012132; GMC_OxRdtase.
IPR000172; GMC_OxRdtase_N.
IPR007867; GMC_OxRtase_C.
Graphical view of domain structure.
Pfam PF05199; GMC_oxred_C; 1.
PF00732; GMC_oxred_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000137; Alcohol_oxidase; 1.
PROSITE PS00623; GMC_OXRED_1; 1.
PS00624; GMC_OXRED_2; 1.
BLOCKS P13006.
Other
LinkHub P13006; -.
ProtoNet P13006.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
3D-structure; Direct protein sequencing; FAD; Flavoprotein; Glycoprotein; Oxidoreductase; Secreted; Signal.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
SIGNAL   1    22  22     Or 48. 
CHAIN   23   605  583     Glucose oxidase. PRO_0000012338
NP_BIND   43    72  30     FAD (Probable). 
ACT_SITE   538   538        By similarity. 
CARBOHYD   111   111        N-linked (GlcNAc...). 
DISULFID   186   228         
HELIX   26    29  4      
HELIX   34    36  3      
TURN   37    39  3      
STRAND   41    47  7      
HELIX   51    60  10      
STRAND   68    74  7      
HELIX   82    85  4      
HELIX   87    89  3      
TURN   90    95  6      
TURN   108   110  3      
HELIX   124   127  4      
HELIX   138   146  9      
HELIX   155   165  11      
STRAND   166   168  3      
HELIX   173   178  6      
HELIX   184   186  3      
STRAND   189   196  8      
HELIX   207   216  10      
TURN   217   219  3      
STRAND   233   235  3      
STRAND   239   241  3      
HELIX   250   254  5      
HELIX   256   258  3      
STRAND   264   269  6      
STRAND   271   278  8      
STRAND   280   283  4      
STRAND   285   294  10      
STRAND   297   309  13      
TURN   313   315  3      
HELIX   316   322  7      
HELIX   328   331  4      
HELIX   332   334  3      
STRAND   352   360  9      
HELIX   362   364  3      
STRAND   369   375  7      
HELIX   376   380  5      
HELIX   381   383  3      
HELIX   384   393  10      
HELIX   395   404  10      
HELIX   411   426  16      
STRAND   431   438  8      
STRAND   442   451  10      
STRAND   456   463  8      
HELIX   465   467  3      
STRAND   470   473  4      
HELIX   480   497  18      
HELIX   500   504  5      
STRAND   506   512  7      
HELIX   513   515  3      
HELIX   522   528  7      
HELIX   529   531  3      
HELIX   548   550  3      
STRAND   558   560  3      
STRAND   564   568  5      
HELIX   583   603  21      
Sequence information
Length: 605 AA [This is the length of the unprocessed precursor] Molecular weight: 65638 Da [This is the MW of the unprocessed precursor] CRC64: 25243E5ED1D2773B [This is a checksum on the sequence]
        10         20         30         40         50         60 
MQTLLVSSLV VSLAAALPHY IRSNGIEASL LTDPKDVSGR TVDYIIAGGG LTGLTTAARL 

        70         80         90        100        110        120 
TENPNISVLV IESGSYESDR GPIIEDLNAY GDIFGSSVDH AYETVELATN NQTALIRSGN 

       130        140        150        160        170        180 
GLGGSTLVNG GTWTRPHKAQ VDSWETVFGN EGWNWDNVAA YSLQAERARA PNAKQIAAGH 

       190        200        210        220        230        240 
YFNASCHGVN GTVHAGPRDT GDDYSPIVKA LMSAVEDRGV PTKKDFGCGD PHGVSMFPNT 

       250        260        270        280        290        300 
LHEDQVRSDA AREWLLPNYQ RPNLQVLTGQ YVGKVLLSQN GTTPRAVGVE FGTHKGNTHN 

       310        320        330        340        350        360 
VYAKHEVLLA AGSAVSPTIL EYSGIGMKSI LEPLGIDTVV DLPVGLNLQD QTTATVRSRI 

       370        380        390        400        410        420 
TSAGAGQGQA AWFATFNETF GDYSEKAHEL LNTKLEQWAE EAVARGGFHN TTALLIQYEN 

       430        440        450        460        470        480 
YRDWIVNHNV AYSELFLDTA GVASFDVWDL LPFTRGYVHI LDKDPYLHHF AYDPQYFLNE 

       490        500        510        520        530        540 
LDLLGQAAAT QLARNISNSG AMQTYFAGET IPGDNLAYDA DLSAWTEYIP YHFRPNYHGV 

       550        560        570        580        590        600 
GTCSMMPKEM GGVVDNAARV YGVQGLRVID GSIPPTQMSS HVMTVFYAMA LKISDAILED 


YASMQ 

P13006 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
 Hosted by ca flag CBR Canada Mirror sites: Australia  Brazil  China  Korea  Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!