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UniProtKB/Swiss-Prot entry P15601


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name NDUS3_PARPR
Primary accession number P15601
Secondary accession numbers None
Integrated into Swiss-Prot on April 1, 1990
Sequence was last modified on April 1, 1990 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 52)
Name and origin of the protein
Protein name NADH-ubiquinone oxidoreductase subunit 9
Synonyms EC 1.6.5.3
EC 1.6.99.3
Protein P1
Gene name
Name: NAD9
From
Paramecium primaurelia [TaxID: 5886] 
Encoded on Mitochondrion.
Taxonomy Eukaryota; Alveolata; Ciliophora; Intramacronucleata; Oligohymenophorea; Peniculida; Parameciidae; Paramecium.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
DOI=10.1016/0378-1119(86)90188-5; PubMed=3023187 [NCBI, ExPASy, EBI, Israel, Japan]
Pritchard A.E., Seilhamer J.J., Cummings D.J.;
"Paramecium mitochondrial DNA sequences and RNA transcripts for cytochrome oxidase subunit I, URF1, and three ORFs adjacent to the replication origin.";
Gene 44:243-253(1986).
Comments
  • FUNCTION: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
  • CATALYTIC ACTIVITY: NADH + ubiquinone = NAD+ + ubiquinol.
  • CATALYTIC ACTIVITY: NADH + acceptor = NAD+ + reduced acceptor.
  • SUBUNIT: Complex I is composed of about 30 different subunits.
  • SUBCELLULAR LOCATION: Mitochondrion inner membrane.
  • SIMILARITY: Belongs to the complex I 30 kDa subunit family.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
M15276; AAA79263.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
3D structure databases
ModBase P15601.
Family and domain databases
InterPro IPR001268; NADH_DHase_Ub_30kDa_su.
Graphical view of domain structure.
Pfam PF00329; Complex1_30kDa; 1.
Pfam graphical view of domain structure.
ProDom PD001581; Complex1_30K; 1.
[Domain structure / List of seq. sharing at least 1 domain]
PROSITE PS00542; COMPLEX1_30K; 1.
BLOCKS P15601.
Other
ProtoNet P15601.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane; NAD; Oxidoreductase; Respiratory chain; Transport; Ubiquinone.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   209  209     NADH-ubiquinone oxidoreductase subunit 9. PRO_0000118646
Sequence information
Length: 209 AA [This is the length of the unprocessed precursor] Molecular weight: 23655 Da [This is the MW of the unprocessed precursor] CRC64: B138B325711DAB43 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSPQRPQRAF FCSEGAKKKK KPKYRFGFPM ALYFFFEKLN FSYWTSTTVS PNHYVCVLPA 

        70         80         90        100        110        120 
AASQALASVL GGELFLGKSQ LVEATAFDLT GQEVAAGDFL VFLKNNGIVL SYSFYFFLLK 

       130        140        150        160        170        180 
KRITFFLHGG EKVCSVEAFY SNANWLEREI SEMFGVSYLL KKDSRNLLLD YGSSFNPFLK 

       190        200 
KFPSTGHTEV VFNSFLKTTA YVQNASVEL 

P15601 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

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