[1]
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NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Liver;
DOI=10.1016/0960-0760(93)90308-J; PubMed=8274401 [NCBI, ExPASy, EBI, Israel, Japan]
Qin K.-N.,
New M.I.,
Cheng K.-C.;
"Molecular cloning of multiple cDNAs encoding human enzymes structurally related to 3 alpha-hydroxysteroid dehydrogenase.";
J. Steroid Biochem. Mol. Biol. 46:673-679(1993).
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[2]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND TISSUE SPECIFICITY.
DOI=10.1074/jbc.270.34.20162; PubMed=7650035 [NCBI, ExPASy, EBI, Israel, Japan]
Khanna M.,
Qin K.-N.,
Wang R.W.,
Cheng K.-C.;
"Substrate specificity, gene structure, and tissue-specific distribution of multiple human 3 alpha-hydroxysteroid dehydrogenases.";
J. Biol. Chem. 270:20162-20168(1995).
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[3]
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NUCLEOTIDE SEQUENCE [MRNA].
DOI=10.1016/0960-0760(95)00019-V; PubMed=7626489 [NCBI, ExPASy, EBI, Israel, Japan]
Khanna M.,
Qin K.-N.,
Cheng K.-C.;
"Distribution of 3 alpha-hydroxysteroid dehydrogenase in rat brain and molecular cloning of multiple cDNAs encoding structurally related proteins in humans.";
J. Steroid Biochem. Mol. Biol. 53:41-46(1995).
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[4]
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NUCLEOTIDE SEQUENCE [MRNA], AND VARIANTS CYS-145 AND VAL-311.
TISSUE=Liver;
PubMed=10634139 [NCBI, ExPASy, EBI, Israel, Japan]
Kume T.,
Iwasa H.,
Shiraishi H.,
Yokoi T.,
Nagashima K.,
Otsuka M.,
Terada T.,
Takagi T.,
Hara A.,
Kamataki T.;
"Characterization of a novel variant (S145C/L311V) of 3alpha-hydroxysteroid/dihydrodiol dehydrogenase in human liver.";
Pharmacogenetics 9:763-771(1999).
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[5]
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NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Liver;
PubMed=10672042 [NCBI, ExPASy, EBI, Israel, Japan]
Nishizawa M.,
Nakajima T.,
Yasuda K.,
Kanzaki H.,
Sasaguri Y.,
Watanabe K.,
Ito S.;
"Close kinship of human 20alpha-hydroxysteroid dehydrogenase gene with three aldo-keto reductase genes.";
Genes Cells 5:111-125(2000).
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[6]
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NUCLEOTIDE SEQUENCE [MRNA], CHARACTERIZATION OF 3-ALPHA-HSD ACTIVITY, AND TISSUE SPECIFICITY.
TISSUE=Liver;
DOI=10.1210/jc.86.2.841; PubMed=11158055 [NCBI, ExPASy, EBI, Israel, Japan]
Dufort I.,
Labrie F.,
Luu-The V.;
"Human types 1 and 3 3 alpha-hydroxysteroid dehydrogenases: differential lability and tissue distribution.";
J. Clin. Endocrinol. Metab. 86:841-846(2001).
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[7]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND VARIANT GLN-250.
DOI=10.1038/nature02462; PubMed=15164054 [NCBI, ExPASy, EBI, Israel, Japan]
Deloukas P.,
Earthrowl M.E.,
Grafham D.V.,
Rubenfield M.,
French L.,
Steward C.A.,
Sims S.K.,
Jones M.C.,
Searle S.,
Scott C.,
Howe K.,
Hunt S.E.,
Andrews T.D.,
Gilbert J.G.R.,
Swarbreck D.,
Ashurst J.L.,
Taylor A.,
Battles J.,
Bird C.P., ![]()
Ainscough R.,
Almeida J.P.,
Ashwell R.I.S.,
Ambrose K.D.,
Babbage A.K.,
Bagguley C.L.,
Bailey J.,
Banerjee R.,
Bates K.,
Beasley H.,
Bray-Allen S.,
Brown A.J.,
Brown J.Y.,
Burford D.C.,
Burrill W.,
Burton J.,
Cahill P.,
Camire D.,
Carter N.P.,
Chapman J.C.,
Clark S.Y.,
Clarke G.,
Clee C.M.,
Clegg S.,
Corby N.,
Coulson A.,
Dhami P.,
Dutta I.,
Dunn M.,
Faulkner L.,
Frankish A.,
Frankland J.A.,
Garner P.,
Garnett J.,
Gribble S.,
Griffiths C.,
Grocock R.,
Gustafson E.,
Hammond S.,
Harley J.L.,
Hart E.,
Heath P.D.,
Ho T.P.,
Hopkins B.,
Horne J.,
Howden P.J.,
Huckle E.,
Hynds C.,
Johnson C.,
Johnson D.,
Kana A.,
Kay M.,
Kimberley A.M.,
Kershaw J.K.,
Kokkinaki M.,
Laird G.K.,
Lawlor S.,
Lee H.M.,
Leongamornlert D.A.,
Laird G.,
Lloyd C.,
Lloyd D.M.,
Loveland J.,
Lovell J.,
McLaren S.,
McLay K.E.,
McMurray A.,
Mashreghi-Mohammadi M.,
Matthews L.,
Milne S.,
Nickerson T.,
Nguyen M.,
Overton-Larty E.,
Palmer S.A.,
Pearce A.V.,
Peck A.I.,
Pelan S.,
Phillimore B.,
Porter K.,
Rice C.M.,
Rogosin A.,
Ross M.T.,
Sarafidou T.,
Sehra H.K.,
Shownkeen R.,
Skuce C.D.,
Smith M.,
Standring L.,
Sycamore N.,
Tester J.,
Thorpe A.,
Torcasso W.,
Tracey A.,
Tromans A.,
Tsolas J.,
Wall M.,
Walsh J.,
Wang H.,
Weinstock K.,
West A.P.,
Willey D.L.,
Whitehead S.L.,
Wilming L.,
Wray P.W.,
Young L.,
Chen Y.,
Lovering R.C.,
Moschonas N.K.,
Siebert R.,
Fechtel K.,
Bentley D.,
Durbin R.M.,
Hubbard T.,
Doucette-Stamm L.,
Beck S.,
Smith D.R.,
Rogers J.;
"The DNA sequence and comparative analysis of human chromosome 10.";
Nature 429:375-381(2004).
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[8]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], AND VARIANT TYR-170.
TISSUE=Liver;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
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[9]
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NUCLEOTIDE SEQUENCE [MRNA] OF 2-323.
TISSUE=Liver;
DOI=10.1021/bi00456a034; PubMed=2187532 [NCBI, ExPASy, EBI, Israel, Japan]
Winters C.J.,
Molowa D.T.,
Guzelian P.S.;
"Isolation and characterization of cloned cDNAs encoding human liver chlordecone reductase.";
Biochemistry 29:1080-1087(1990).
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[10]
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NUCLEOTIDE SEQUENCE [MRNA] OF 3-323, AND PROTEIN SEQUENCE OF 5-29; 76-131; 184-201 AND 271-294.
TISSUE=Liver;
PubMed=8172617 [NCBI, ExPASy, EBI, Israel, Japan]
Deyashiki Y.,
Ogasawara A.,
Nakayama T.,
Nakanishi M.,
Miyabe Y.,
Sato K.,
Hara A.;
"Molecular cloning of two human liver 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase isoenzymes that are identical with chlordecone reductase and bile-acid binder.";
Biochem. J. 299:545-552(1994).
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[11]
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PROTEIN SEQUENCE OF 40-54; 105-121; 162-175; 184-196; 277-291 AND 307-321, AND CHARACTERIZATION AS 3-ALPHA-HSD.
DOI=10.1016/0006-291X(92)91260-W; PubMed=1530633 [NCBI, ExPASy, EBI, Israel, Japan]
Binstock J.M.,
Iyer R.B.,
Hamby C.V.,
Fried V.A.,
Schwartz I.S.,
Weinstein B.I.,
Southren A.L.;
"Human hepatic 3 alpha-hydroxysteroid dehydrogenase: possible identity with human hepatic chlordecone reductase.";
Biochem. Biophys. Res. Commun. 187:760-766(1992).
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[12]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-196, AND MASS SPECTROMETRY.
TISSUE=Epithelium;
DOI=10.1021/pr070152u; PubMed=17924679 [NCBI, ExPASy, EBI, Israel, Japan]
Yu L.-R.,
Zhu Z.,
Chan K.C.,
Issaq H.J.,
Dimitrov D.S.,
Veenstra T.D.;
"Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra.";
J. Proteome Res. 6:4150-4162(2007).
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[13]
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X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) IN COMPLEX WITH NADP.
Structural genomics consortium (SGC);
"Crystal structure of human 3-alpha hydroxysteroid/dihydrodiol dehydrogenase (AKR1C4) complexed with NADP+.";
Submitted (FEB-2006) to the PDB data bank.
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