[1]	NUCLEOTIDE SEQUENCE [GENOMIC DNA]. STRAIN=ATCC 29999 / Hb / DSM 3368 / NCIB 12670; PubMed=2204626 [NCBI, ExPASy, EBI, Israel, Japan] Szittner R., Meighen E.; "Nucleotide sequence, expression, and properties of luciferase coded by lux genes from a terrestrial bacterium."; J. Biol. Chem. 265:16581-16587(1990).
[2]	NUCLEOTIDE SEQUENCE [GENOMIC DNA]. STRAIN=ATCC 29999 / Hb / DSM 3368 / NCIB 12670; PubMed=1644764 [NCBI, ExPASy, EBI, Israel, Japan] Meighen E.A., Szittner R.B.; "Multiple repetitive elements and organization of the lux operons of luminescent terrestrial bacteria."; J. Bacteriol. 174:5371-5381(1992).
[3]	NUCLEOTIDE SEQUENCE [GENOMIC DNA]. STRAIN=Hm; DOI=10.1016/0006-291X(90)92106-A; PubMed=2383248 [NCBI, ExPASy, EBI, Israel, Japan] Johnston T.C., Rucker E.B., Cochrum L., Hruska K.S., Vandegrift V.; "The nucleotide sequence of the luxA and luxB genes of Xenorhabdus luminescens HM and a comparison of the amino acid sequences of luciferases from four species of bioluminescent bacteria."; Biochem. Biophys. Res. Commun. 170:407-415(1990).

Comments

FUNCTION: Light-emitting reaction in luminous bacteria.
CATALYTIC ACTIVITY: RCHO + reduced FMN + O₂ = RCOOH + FMN + H₂O + light.
SUBUNIT: Heterodimer of an alpha and a beta chain.
MISCELLANEOUS: The synthesis of this protein is regulated by a complex control mechanism that has been termed autoinduction.
SIMILARITY: Belongs to the bacterial luciferase oxidoreductase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

M57416; AAA27623.1; -; Genomic_DNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]
M90093; AAA27619.1; -; Genomic_DNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]
M55977; AAA27626.1; -; Genomic_DNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]

PIR

B35411; B35411.

3D structure databases

HSSP

P07740; 1BRL. [HSSP ENTRY / PDB]

ModBase

P19839.

Family and domain databases

InterPro

IPR011251; Luciferase-like_bac.
IPR002103; Luciferase_bac.
IPR016048; Luciferase_mOase.
Graphical view of domain structure.

Gene3D

G3DSA:3.20.20.30; Luciferase_like; 1.

Pfam

PF00296; Bac_luciferase; 1.
Pfam graphical view of domain structure.

PRINTS

PR00089; LUCIFERASE.

PROSITE

PS00494; BACTERIAL_LUCIFERASE; 1.

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Flavoprotein; FMN; Luminescence; Monooxygenase; Oxidoreductase; Photoprotein.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 360`	`360`		`Alkanal monooxygenase alpha chain.`	`PRO_0000220167`

Sequence information

Length: 360 AA [This is the length of the unprocessed precursor]

Molecular weight: 41001 Da [This is the MW of the unprocessed precursor]

CRC64: 9410729A95DFB93E [This is a checksum on the sequence]

        10         20         30         40         50         60 
MKFGNFLLTY QPPQFSQTEV MKRLVKLGRI SEECGFDTVW LLEHHFTEFG LLGNPYVAAA 

        70         80         90        100        110        120 
YLLGATKKLN VGTAAIVLPT AHPVRQLEDV NLLDQMSKGR FRFGICRGLY NKDFRVFGTD 

       130        140        150        160        170        180 
MNNSRALAEC WYGLIKNGMT EGYMEADNEH IKFHKVKVNP AAYSRGGAPV YVVAESASTT 

       190        200        210        220        230        240 
EWAAQFGLPM ILSWIINTNE KKAQLELYNE VAQEYGHDIH NIDHCLSYIT SVDHDSIKAK 

       250        260        270        280        290        300 
EICRKFLGHW YDSYVNATTI FDDSDQTRGY DFNKGQWRDF VLKGHKDTNR RIDYSYEINP 

       310        320        330        340        350        360 
VGTPQECIDI IQKDIDATGI SNICCGFEAN GTVDEIIASM KLFQSDVMPF LKEKQRSLLY

P19839 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools