ID   LUXA_PHOPO              Reviewed;         346 AA.
AC   P24113;
DT   01-MAR-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-1992, sequence version 1.
DT   25-NOV-2008, entry version 45.
DE   RecName: Full=Alkanal monooxygenase alpha chain;
DE            EC=1.14.14.3;
DE   AltName: Full=Bacterial luciferase alpha chain;
GN   Name=luxA;
OS   Photobacterium phosphoreum.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales;
OC   Vibrionaceae; Photobacterium.
OX   NCBI_TaxID=659;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   MEDLINE=91207448; PubMed=2018544; DOI=10.1016/0006-291X(91)90959-B;
RA   Ferri S.R., Soly R.R., Szittner R.B., Meighen E.A.;
RT   "Structure and properties of luciferase from Photobacterium
RT   phosphoreum.";
RL   Biochem. Biophys. Res. Commun. 176:541-548(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-41.
RX   MEDLINE=91302295; PubMed=2071574;
RA   Ferri S.R., Meighen E.A.;
RT   "A lux-specific myristoyl transferase in luminescent bacteria related
RT   to eukaryotic serine esterases.";
RL   J. Biol. Chem. 266:12852-12857(1991).
CC   -!- FUNCTION: Light-emitting reaction in luminous bacteria.
CC   -!- CATALYTIC ACTIVITY: RCHO + reduced FMN + O(2) = RCOOH + FMN +
CC       H(2)O + light.
CC   -!- SUBUNIT: Heterodimer of an alpha and a beta chain.
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DR   EMBL; M65067; AAA70297.1; -; Genomic_DNA.
DR   EMBL; M64224; AAA25627.1; -; Genomic_DNA.
DR   PIR; JH0387; JH0387.
DR   HSSP; P07740; 1LUC.
DR   KEGG; son:SO_1467; -.
DR   GO; GO:0047646; F:alkanal monooxygenase (FMN-linked) activity; IEA:EC.
DR   GO; GO:0008218; P:bioluminescence; IEA:InterPro.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   InterPro; IPR011251; Luciferase-like_bac.
DR   InterPro; IPR002103; Luciferase_bac.
DR   InterPro; IPR016048; Luciferase_mOase.
DR   Gene3D; G3DSA:3.20.20.30; Luciferase_like; 1.
DR   Pfam; PF00296; Bac_luciferase; 1.
DR   PRINTS; PR00089; LUCIFERASE.
DR   PROSITE; PS00494; BACTERIAL_LUCIFERASE; 1.
PE   4: Predicted;
KW   Flavoprotein; FMN; Luminescence; Monooxygenase; Oxidoreductase;
KW   Photoprotein.
FT   CHAIN         1    346       Alkanal monooxygenase alpha chain.
FT                                /FTId=PRO_0000220169.
FT   CONFLICT      6      6       I -> IC (in Ref. 2; AAA25627).
FT   CONFLICT     40     41       LE -> TL (in Ref. 2; AAA25627).
SQ   SEQUENCE   346 AA;  39364 MW;  360EC324E0A438A0 CRC64;
     MKFGNIFSYQ PPGESHKEVM DRFVRLGVAS EELNFDTYWL EHHFTEFGLT GNLFVACANL
     LGRTTKLNVG TMIVLPTAHP ARQMEDLLLL DQMSKGRFNF GVVRGYHKDF RVFGVTMEDS
     RAITEDFHTM IMDGTKTGLH TDGKNIEFPD VNVYPEAYLE KIPTCMTAES ATTTWLAERG
     LPMVLSWIIT TSEKKAQMEL YNAVRDSGYS EEYIKNVDHS MTLICSVDED GKKAEDVREF
     LGNWYDSYVN ATNIFSESNQ TRGYDYHKGQ KDFVLQGHTN TKRRVDYSND LNPVGTPEKC
     IEIQRDIDAT GITNITLGFE ANGSEEEIIA SMKRFMQVAP FLKDPK
//