ID   AL7A1_PEA               Reviewed;         508 AA.
AC   P25795;
DT   01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   04-NOV-2008, entry version 53.
DE   RecName: Full=Aldehyde dehydrogenase family 7 member A1;
DE            EC=1.2.1.3;
DE   AltName: Full=Turgor-responsive protein 26G;
DE   AltName: Full=Antiquitin-1;
OS   Pisum sativum (Garden pea).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons;
OC   rosids; eurosids I; Fabales; Fabaceae; Papilionoideae; Fabeae; Pisum.
OX   NCBI_TaxID=3888;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Progress No. 9;
RX   MEDLINE=91355842; PubMed=1715781; DOI=10.1007/BF00017720;
RA   Guerrero F.D., Jones J.T., Mullet J.E.;
RT   "Turgor-responsive gene transcription and RNA levels increase rapidly
RT   when pea shoots are wilted. Sequence and expression of three inducible
RT   genes.";
RL   Plant Mol. Biol. 15:11-26(1990).
RN   [2]
RP   PROTEIN SEQUENCE OF 2-16.
RX   MEDLINE=21956475; PubMed=11959129; DOI=10.1016/S0014-5793(02)02553-X;
RA   Tang W.-K., Cheng C.H.K., Fong W.-P.;
RT   "First purification of the antiquitin protein and demonstration of its
RT   enzymatic activity.";
RL   FEBS Lett. 516:183-186(2002).
CC   -!- CATALYTIC ACTIVITY: An aldehyde + NAD(+) + H(2)O = an acid + NADH.
CC   -!- SUBUNIT: Homotetramer (By similarity).
CC   -!- INDUCTION: By dehydration of shoots but not roots and not by heat
CC       shock or ABA.
CC   -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
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DR   EMBL; X54359; CAA38243.1; -; mRNA.
DR   PIR; S11863; S11863.
DR   HSSP; P51977; 1BXS.
DR   GO; GO:0004029; F:aldehyde dehydrogenase (NAD) activity; IEA:EC.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   GO; GO:0006950; P:response to stress; IEA:UniProtKB-KW.
DR   InterPro; IPR016160; Ald_DHase_CS.
DR   InterPro; IPR016162; Ald_DHase_N.
DR   InterPro; IPR015590; Aldehyde_DHase.
DR   Gene3D; G3DSA:3.40.605.10; Aldehyde_dehydrogenase_N; 1.
DR   PANTHER; PTHR11699; Aldehyde_dehyd; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; FALSE_NEG.
DR   PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; NAD; Oxidoreductase; Stress response.
FT   INIT_MET      1      1       Removed.
FT   CHAIN         2    508       Aldehyde dehydrogenase family 7 member
FT                                A1.
FT                                /FTId=PRO_0000056498.
FT   NP_BIND     244    249       NAD (By similarity).
FT   ACT_SITE    266    266       Proton acceptor (By similarity).
FT   ACT_SITE    300    300       Nucleophile (By similarity).
FT   SITE        165    165       Transition state stabilizer (By
FT                                similarity).
SQ   SEQUENCE   508 AA;  53789 MW;  CC88F367B52E923D CRC64;
     MGSDSNNLGF LKEIGLGATN IGSFINGQWK ANGPTVHSVN PSTNQVIASV TEATLDDYEE
     GLRASSEAAK TWRTVPAPKR GEIVRQIGDA LRAKLDPLGR LVALEMGKIL AEGIGEVQEI
     IDMCDYSVGL SRQLNGSIIP SERPEHMMFE VWNPLGIVGV ITAFNFPCAV LGWNACIALV
     GGNTVVWKGA PTTPLITVAV TKLIAEVFER NNLPGAIFTA LCGGADIGHA IAKDTRIPLV
     SFTGSSKVGA LVQQTVSQRF GKTLLELSGN NAIIVMDDAD ITLAVRSIFF AAVGTAGQRC
     TTCRRLYLHE SVYANVLEQL TALYKQVKIG NPLEEGTLVG PLHTRSAVEN FKNGISAIKS
     QGGKIVTGGS VLESEGNFVV PTIVEISADA AVVKEELFAP VLYVMKFKDL EEAIALNNSV
     PQGLSSSIFT QKPSTIFKWI GPSGSDCGIV NVNIPTNGAE IGGAFGGEKA TGGGREAGSD
     SWKQYMRRST CTINYGSELP LAQGINFG
//