NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=ATCC 25521 / L1 / CIP 665;
PubMed=1915359 [NCBI, ExPASy, EBI, Israel, Japan]
Lee C.Y., Szittner R.B., Meighen E.A.;
"The lux genes of the luminous bacterial symbiont, Photobacterium leiognathi, of the ponyfish. Nucleotide sequence, difference in gene organization, and high expression in mutant Escherichia coli.";
Eur. J. Biochem. 201:161-167(1991).

Comments

FUNCTION: LuxC is the fatty acid reductase enzyme responsible for synthesis of the aldehyde substrate for the luminescent reaction catalyzed by luciferase.
CATALYTIC ACTIVITY: A long-chain aldehyde + CoA + NADP⁺ = a long-chain acyl-CoA + NADPH.
PATHWAY: Lipid metabolism; bioluminescent fatty acid reduction .
SIMILARITY: Belongs to the luxC family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

M63594; AAA25616.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

PIR

S17836; S17836.

3D structure databases

ModBase

P29236.

Ontologies

GO:0050062;	Molecular function: long-chain-fatty-acyl-CoA reductase activity (inferred from electronic annotation from EC).
QuickGo view.

Family and domain databases

InterPro

IPR008670; LuxC.
Graphical view of domain structure.

Pfam

PF05893; LuxC; 1.
Pfam graphical view of domain structure.

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Luminescence; NADP; Oxidoreductase.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 478`	`478`		`Acyl-CoA reductase.`	`PRO_0000220197`

Sequence information

Length: 478 AA [This is the length of the unprocessed precursor]

Molecular weight: 53713 Da [This is the MW of the unprocessed precursor]

CRC64: 4716EF699BF7FE4A [This is a checksum on the sequence]

        10         20         30         40         50         60 
MIKKIPMIIG GVVQNTSGYG MRELTLNNNK VNIPIITQSD VEAIQSLNIE NKLTINQIVN 

        70         80         90        100        110        120 
FLYTVGQKWK SETYSRRLTY IRDLIKFLGY SQEMAKLEAN WISMILCSKS ALYDIVENDL 

       130        140        150        160        170        180 
SSRHIIDEWI PQGECYVKAL PKGKSVHLLA GNVPLSGVTS ILRAILTKNE CIIKTSSADP 

       190        200        210        220        230        240 
FTATALVNSF IDVDAEHPIT RSISVMYWSH SEDLAIPKQI MSCADVVIAW GGDDAIKWAT 

       250        260        270        280        290        300 
EHAPSHADIL KFGPKKSISI VDNPTDIKAA AIGVAHDICF YDQQACFSTQ DIYYIGDSID 

       310        320        330        340        350        360 
IFFDELAQQL NKYKDILPKG ERNFDEKAAF SLTERECLFA KYKVQKGESQ SWLLTQSPAG 

       370        380        390        400        410        420 
SFGNQPLSRS AYIHQVNDIS EVIPFVHKAV TQTVAIAPWE SSFKYRDILA EHGAERIIEA 

       430        440        450        460        470 
GMNNIFRVGG AHDGMRPLQR LVNYISHERP STYTTKDVSV KIEQTRYLEE DKFLVFVP

P29236 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools