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UniProtKB/Swiss-Prot entry P29422

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name CATA_MICLU
Primary accession number P29422
Secondary accession number Q8RK91
Integrated into Swiss-Prot on April 1, 1993
Sequence was last modified on December 6, 2002 (Sequence version 2)
Annotations were last modified on    November 25, 2008 (Entry version 68)
Name and origin of the protein
Protein name Catalase
Synonym EC 1.11.1.6
Gene name
Name: katA
From
Micrococcus luteus (Micrococcus lysodeikticus) [TaxID: 1270] 
Taxonomy Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; Micrococcineae; Micrococcaceae; Micrococcus.
Protein existence 1: Evidence at protein level;
References
[1]
 PRELIMINARY PROTEIN SEQUENCE, AND X-RAY CRYSTALLOGRAPHY (1.5 ANGSTROMS).
DOI=10.1016/0014-5793(92)80919-8; PubMed=1426241 [NCBI, ExPASy, EBI, Israel, Japan]
Murshudov G.N., Melik-Adamyan W.R., Grebenko A.I., Barynin V.V., Vagin A.A., Vainshtein B.K., Dauter Z., Wilson K.S.;
"Three-dimensional structure of catalase from Micrococcus lysodeikticus at 1.5-A resolution.";
FEBS Lett. 312:127-131(1992).
[2]
 NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND X-RAY CRYSTALLOGRAPHY (0.88 ANGSTROMS).
DOI=10.1107/S0907444902016566; PubMed=12454454 [NCBI, ExPASy, EBI, Israel, Japan]
Murshudov G.N., Grebenko A.I., Brannigan J.A., Antson A.A., Barynin V.V., Dodson G.G., Dauter Z., Wilson K.S., Melik-Adamyan W.R.;
"The structures of Micrococcus lysodeikticus catalase, its ferryl intermediate (compound II) and NADPH complex.";
Acta Crystallogr. D 58:1972-1982(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AJ438208; CAD27348.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR S27264; S27264.
3D structure databases
PDB
1GWE; X-ray; 0.88 A; A=1-502.[ExPASy / RCSB / EBI]
1GWF; X-ray; 1.96 A; A=1-502.[ExPASy / RCSB / EBI]
1GWH; X-ray; 1.74 A; A=1-502.[ExPASy / RCSB / EBI]
1HBZ; X-ray; 1.50 A; A=6-502.[ExPASy / RCSB / EBI]
Detailed list of linked structures.
PDBsum 1GWE; -.
1GWF; -.
1GWH; -.
1HBZ; -.
ModBase P29422.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from UniProtKB-KW).
GO:0004096; Molecular function: catalase activity (inferred from electronic annotation from InterPro).
GO:0005506; Molecular function: iron ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0042744; Biological process: hydrogen peroxide catabolic process (inferred from electronic annotation from UniProtKB-KW).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR002226; Catalase.
IPR011614; Catalase_N.
Graphical view of domain structure.
Gene3D G3DSA:2.40.180.10; Catalase_N; 1.
PANTHER PTHR11465; Catalase; 1.
Pfam PF00199; Catalase; 1.
Pfam graphical view of domain structure.
PRINTS PR00067; CATALASE.
ProDom PD000510; Catalase; 1.
[Domain structure / List of seq. sharing at least 1 domain]
PROSITE PS00437; CATALASE_1; 1.
PS00438; CATALASE_2; 1.
PS51402; CATALASE_3; 1.
PROSITE graphical view of domain structure (profiles).
ProtoNet P29422.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
3D-structure; Cytoplasm; Direct protein sequencing; Heme; Hydrogen peroxide; Iron; Metal-binding; NADP; Oxidoreductase; Peroxidase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   503  503     Catalase. PRO_0000084990
ACT_SITE   61    61         
ACT_SITE   133   133         
METAL   343   343        Iron (heme axial ligand). 
STRAND   18    20  3      
STRAND   22    25  4      
TURN   31    33  3      
HELIX   41    50  10      
STRAND   63    73  11      
TURN   78    80  3      
HELIX   84    86  3      
STRAND   91    99  9      
STRAND   101   103  3      
STRAND   116   123  8      
STRAND   126   136  11      
HELIX   143   145  3      
HELIX   146   153  8      
TURN   157   159  3      
HELIX   164   172  9      
HELIX   175   177  3      
HELIX   178   185  8      
HELIX   187   189  3      
STRAND   190   192  3      
HELIX   194   196  3      
STRAND   205   208  4      
STRAND   214   223  10      
HELIX   232   241  10      
HELIX   245   255  11      
STRAND   261   270  10      
HELIX   273   276  4      
TURN   290   292  3      
STRAND   296   305  10      
HELIX   310   313  4      
TURN   314   316  3      
HELIX   334   350  17      
HELIX   355   357  3      
HELIX   359   361  3      
STRAND   386   389  4      
STRAND   391   393  3      
STRAND   408   415  8      
HELIX   428   436  9      
HELIX   440   454  15      
HELIX   459   472  14      
HELIX   474   485  12      
Sequence information
Length: 503 AA [This is the length of the unprocessed precursor] Molecular weight: 56906 Da [This is the MW of the unprocessed precursor] CRC64: 8C60ADEFC0E46A09 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MEHQKTTPHA TGSTRQNGAP AVSDRQSLTV GSEGPIVLHD THLLETHQHF NRMNIPERRP 

        70         80         90        100        110        120 
HAKGSGAFGE FEVTEDVSKY TKALVFQPGT KTETLLRFST VAGELGSPDT WRDVRGFALR 

       130        140        150        160        170        180 
FYTEEGNYDL VGNNTPIFFL RDPMKFTHFI RSQKRLPDSG LRDATMQWDF WTNNPESAHQ 

       190        200        210        220        230        240 
VTYLMGPRGL PRTWREMNGY GSHTYLWVNA QGEKHWVKYH FISQQGVHNL SNDEATKIAG 

       250        260        270        280        290        300 
ENADFHRQDL FESIAKGDHP KWDLYIQAIP YEEGKTYRFN PFDLTKTISQ KDYPRIKVGT 

       310        320        330        340        350        360 
LTLNRNPENH FAQIESAAFS PSNTVPGIGL SPDRMLLGRA FAYHDAQLYR VGAHVNQLPV 

       370        380        390        400        410        420 
NRPKNAVHNY AFEGQMWYDH TGDRSTYVPN SNGDSWSDET GPVDDGWEAD GTLTREAQAL 

       430        440        450        460        470        480 
RADDDDFGQA GTLVREVFSD QERDDFVETV AGALKGVRQD VQARAFEYWK NVDATIGQRI 

       490        500 
EDEVKRHEGD GIPGVEAGGE ARM
P29422 in FASTA format

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