[1]	NUCLEOTIDE SEQUENCE. STRAIN=cv. D&PL 415; DOI=10.1007/BF00028744; PubMed=1932700 [NCBI, ExPASy, EBI, Israel, Japan] Isin S.H., Allen R.D.; "Isolation and characterization of a pea catalase cDNA."; Plant Mol. Biol. 17:1263-1265(1991).
[2]	NUCLEOTIDE SEQUENCE. STRAIN=cv. Corsoy 79; Su H., Hardy K.A., Hermsmeier D., Baum T.J.; Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases.

Comments

FUNCTION: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
CATALYTIC ACTIVITY: 2 H₂O₂ = O₂ + 2 H₂O.
COFACTOR: Heme group.
SUBUNIT: Homotetramer.
SUBCELLULAR LOCATION: Peroxisome (By similarity). Glyoxysome (By similarity).
SIMILARITY: Belongs to the catalase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

Z12021; CAA78056.1; -; Genomic_DNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]
AF035252; AAB88169.1; -; mRNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]
AF035253; AAB88170.1; -; mRNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]

PIR

S20999; CSSY.

UniGene

Gma.28718

3D structure databases

HSSP

P46206; 1M7S. [HSSP ENTRY / PDB]

ModBase

P29756.

Protein family/group databases

PeroxiBase

6260; GmKat01.

Family and domain databases

InterPro

IPR002226; Catalase.
IPR011614; Catalase_N.
Graphical view of domain structure.

Gene3D

G3DSA:2.40.180.10; Catalase_N; 1.

PANTHER

PTHR11465; Catalase; 1.

Pfam

PF00199; Catalase; 1.
Pfam graphical view of domain structure.

PRINTS

PR00067; CATALASE.

ProDom

PD000510; Catalase; 1.
[Domain structure / List of seq. sharing at least 1 domain]

PROSITE

PS00437; CATALASE_1; 1.
PS00438; CATALASE_2; 1.

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Glyoxysome; Heme; Hydrogen peroxide; Iron; Metal-binding; Oxidoreductase; Peroxidase; Peroxisome.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 492`	`492`	`Catalase-1/2.`	`PRO_0000084963`
`ACT_SITE`	`65 65`		`By similarity.`
`ACT_SITE`	`138 138`		`By similarity.`
`METAL`	`348 348`		`Iron (heme axial ligand) (By similarity).`

Sequence information

Length: 492 AA [This is the length of the unprocessed precursor]

Molecular weight: 56847 Da [This is the MW of the unprocessed precursor]

CRC64: CE8AFE8BEEA483C6 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MDPYKNRPSS AFNSPFWTTN SGAPIWNNNS SLTVGSRGPI LLEDYHLVEK LANFDRERIP 

        70         80         90        100        110        120 
ERVVHARGAS AKGFFEVTHD ISHLTCADFL RAPGVQTPLI VRFSTVIHER GSPETLRDPR 

       130        140        150        160        170        180 
GFAVKFYTRE GNFDLVGNNF PVFFVRDGLK FPDMVHALKP NPKSHIQENW RILDFFSHHP 

       190        200        210        220        230        240 
ESLHMFSFLF DDVGIPQDYR HMDGFGVNTY TLINKAGKAL YVKFHWKTTS GEKSLLDDEA 

       250        260        270        280        290        300 
IRVGGSNHSH ATQDLYDSIA AGNYPEWKLY IQTLDPENED RLDFDPLDVT KTWPEDVLPL 

       310        320        330        340        350        360 
QPVGRMVLNK NIDNFFAENE QLAFCPAIIV PGVYYSDDKL LQTRVFSYAD TQRHRLGPNY 

       370        380        390        400        410        420 
LQLPANAPKC AHHNNHHDGF MNFMHRDEEV NYFPSRYDPV RHAEKVPVPP RILGGKREKC 

       430        440        450        460        470        480 
MIEKENNFKQ PGERYRSWPS DRQERFVRRW VDALSDPRVT HEIRSIWISY WSQADRSLGQ 

       490 
KIASHLNLKP SI

P29756 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools