[1]	NUCLEOTIDE SEQUENCE [MRNA]. STRAIN=cv. Xanthi NC; TISSUE=Leaf mesophyll; PubMed=1729717 [NCBI, ExPASy, EBI, Israel, Japan] Takahashi Y., Nagata T.; "parB: an auxin-regulated gene encoding glutathione S-transferase."; Proc. Natl. Acad. Sci. U.S.A. 89:56-59(1992).

Comments

FUNCTION: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
CATALYTIC ACTIVITY: RX + glutathione = HX + R-S-glutathione.
DEVELOPMENTAL STAGE: Its expression was observed during transition from G0 to the S phase of tobacco mesophyll protoplasts in vitro.
INDUCTION: By auxin.
SIMILARITY: Belongs to the GST superfamily. Phi family.
SIMILARITY: Contains 1 GST C-terminal domain.
SIMILARITY: Contains 1 GST N-terminal domain.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

D10524; BAA01394.1; -; mRNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

PIR

A41789; A41789.

3D structure databases

HSSP

P46422; 1GNW. [HSSP ENTRY / PDB]

ModBase

P30109.

Ontologies

GO:0004364;	Molecular function: glutathione transferase activity (inferred from electronic annotation from EC).
QuickGo view.

Family and domain databases

InterPro

IPR010987; Glutathione-S-Trfase_C-like.
IPR004046; GST_C.
IPR004045; GST_N.
IPR012335; Thioredoxin_fold.
Graphical view of domain structure.

Gene3D

G3DSA:1.20.1050.10; GST_C_like; 1.
G3DSA:3.40.30.10; Thioredoxin_fold; 1.

Pfam

PF00043; GST_C; 1.
PF02798; GST_N; 1.
Pfam graphical view of domain structure.

PROSITE

PS50405; GST_CTER; 1.
PS50404; GST_NTER; 1.
PROSITE graphical view of domain structure (profiles).

ProtoNet

P30109.

Other

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Transferase.

Features

Feature table viewer

Feature aligner

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 213`	`213`	`Glutathione S-transferase PARB.`	`PRO_0000185856`
`DOMAIN`	`1 82`	`82`	`GST N-terminal.`
`DOMAIN`	`89 213`	`125`	`GST C-terminal.`

Sequence information

Length: 213 AA [This is the length of the unprocessed precursor]

Molecular weight: 23967 Da [This is the MW of the unprocessed precursor]

CRC64: 0AB971171E7CCFDC [This is a checksum on the sequence]

        10         20         30         40         50         60 
MAIKVHGSPM STATMRVAAC LIEKELDFEF VPVDMASGEH KKHPYLSLNP FGQVPAFEDG 

        70         80         90        100        110        120 
DLKLFESRAI TQYIAHVYAD NGYQLILQDP KKMPSMSVWM EVEGQKFEPP ATKLTWELGI 

       130        140        150        160        170        180 
KPIIGMTTDD AAVKESEAQL SKVLDIYETQ LAESKYLGGD SFTLVDLHHI PNIYYLMSSK 

       190        200        210 
VKEVFDSRPR VSAWCADILA RPAWVKGLEK LQK

P30109 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools