[1]	NUCLEOTIDE SEQUENCE [GENOMIC DNA]. STRAIN=cv. Cheyenne; PubMed=1799693 [NCBI, ExPASy, EBI, Israel, Japan] Dudler R., Hertig C., Rebmann G., Bull J., Mauch F.; "A pathogen-induced wheat gene encodes a protein homologous to glutathione-S-transferases."; Mol. Plant Microbe Interact. 4:14-18(1991).

Comments

FUNCTION: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
CATALYTIC ACTIVITY: RX + glutathione = HX + R-S-glutathione.
INDUCTION: By pathogen infection.
SIMILARITY: Belongs to the GST superfamily. Phi family.
SIMILARITY: Contains 1 GST C-terminal domain.
SIMILARITY: Contains 1 GST N-terminal domain.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

X56012; CAA39487.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

PIR

T06509; T06509.

3D structure databases

HSSP

P12653; 1AXD. [HSSP ENTRY / PDB]

ModBase

P30110.

Organism-specific databases

Gramene

P30110; -.

Ontologies

GO:0004364;	Molecular function: glutathione transferase activity (inferred from electronic annotation from EC).
QuickGo view.

Family and domain databases

InterPro

IPR010987; Glutathione-S-Trfase_C-like.
IPR004046; GST_C.
IPR004045; GST_N.
IPR012335; Thioredoxin_fold.
Graphical view of domain structure.

Gene3D

G3DSA:1.20.1050.10; GST_C_like; 1.
G3DSA:3.40.30.10; Thioredoxin_fold; 1.

Pfam

PF00043; GST_C; 1.
PF02798; GST_N; 1.
Pfam graphical view of domain structure.

PROSITE

PS50405; GST_CTER; 1.
PS50404; GST_NTER; 1.
PROSITE graphical view of domain structure (profiles).

ProtoNet

P30110.

Other

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Transferase.

Features

Feature table viewer

Feature aligner

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 229`	`229`	`Glutathione S-transferase 1.`	`PRO_0000185858`
`DOMAIN`	`2 83`	`82`	`GST N-terminal.`
`DOMAIN`	`93 223`	`131`	`GST C-terminal.`
`VARIANT`	`34 34`	`1`	`M -> V.`
`VARIANT`	`171 171`	`1`	`T -> S (in strain: cv. Fidel).`
`VARIANT`	`195 195`	`1`	`D -> E (in strain: cv. Fidel).`
`VARIANT`	`226 226`	`1`	`G -> R (in strain: cv. Fidel).`

Sequence information

Length: 229 AA [This is the length of the unprocessed precursor]

Molecular weight: 25828 Da [This is the MW of the unprocessed precursor]

CRC64: C6A2543D53678570 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MSPVKVFGHP MLTNVARVLL FLEEVGAEYE LVPMDFVAGE HKRPQHVQLN PFAKMPGFQD 

        70         80         90        100        110        120 
GDLVLFESRA IAKYILRKYG GTAGLDLLGE NSGIEELAMV DVWTEVEAQQ YYPAISPVVF 

       130        140        150        160        170        180 
ECIIIPFIIP GGGAAPNQTV VDESLERLRG VLGIYEARLE KSRYLAGDSI TFADLNHIPF 

       190        200        210        220 
TFYFMTTPYA KVFDDYPKVK AWWEMLMARP AVQRVCKHMP TEFKLGAQY

P30110 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools