ID   CATA_LACSK              Reviewed;         478 AA.
AC   P30265;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   15-JUL-1999, sequence version 2.
DT   25-NOV-2008, entry version 51.
DE   RecName: Full=Catalase;
DE            EC=1.11.1.6;
GN   Name=katA;
OS   Lactobacillus sakei.
OC   Bacteria; Firmicutes; Lactobacillales; Lactobacillaceae;
OC   Lactobacillus.
OX   NCBI_TaxID=1599;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=LTH677;
RX   MEDLINE=92246494; PubMed=1575485;
RA   Knauf H.J., Vogel R.F., Hammes W.P.;
RT   "Cloning, sequence, and phenotypic expression of katA, which encodes
RT   the catalase of Lactobacillus sake LTH677.";
RL   Appl. Environ. Microbiol. 58:832-839(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND SEQUENCE REVISION.
RC   STRAIN=LTH677;
RX   MEDLINE=98207840; PubMed=9546173;
RA   Hertel C., Schmidt G., Fischer M., Oellers K., Hammes W.P.;
RT   "Oxygen-dependent regulation of the expression of the catalase gene
RT   katA of Lactobacillus sakei LTH677.";
RL   Appl. Environ. Microbiol. 64:1359-1365(1998).
CC   -!- FUNCTION: Decomposes hydrogen peroxide into water and oxygen;
CC       serves to protect cells from the toxic effects of hydrogen
CC       peroxide.
CC   -!- CATALYTIC ACTIVITY: 2 H(2)O(2) = O(2) + 2 H(2)O.
CC   -!- COFACTOR: Heme group.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (Probable).
CC   -!- SIMILARITY: Belongs to the catalase family.
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DR   EMBL; M84015; AAC19139.1; -; Genomic_DNA.
DR   PIR; T09652; T09652.
DR   HSSP; P42321; 1M85.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0004096; F:catalase activity; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0042744; P:hydrogen peroxide catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   InterPro; IPR002226; Catalase.
DR   InterPro; IPR011614; Catalase_N.
DR   Gene3D; G3DSA:2.40.180.10; Catalase_N; 1.
DR   PANTHER; PTHR11465; Catalase; 1.
DR   Pfam; PF00199; Catalase; 1.
DR   PRINTS; PR00067; CATALASE.
DR   ProDom; PD000510; Catalase; 1.
DR   PROSITE; PS00437; CATALASE_1; 1.
DR   PROSITE; PS00438; CATALASE_2; 1.
DR   PROSITE; PS51402; CATALASE_3; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Heme; Hydrogen peroxide; Iron; Metal-binding;
KW   Oxidoreductase; Peroxidase.
FT   CHAIN         1    478       Catalase.
FT                                /FTId=PRO_0000084989.
FT   ACT_SITE     53     53       By similarity.
FT   ACT_SITE    126    126       By similarity.
FT   METAL       336    336       Iron (heme axial ligand) (By similarity).
SQ   SEQUENCE   478 AA;  54076 MW;  85952A05DB16EF3D CRC64;
     MTNQLTTNEG QPWADNQHSQ TAGQRGPVLI QDYQLLEKLA HFNRERIPER VVHAKGAGAK
     GYFKVTKDMS AYTKAAVFSG VGKKTPLITR FSQVAGEAGY PDTYRDVRGF AVKFYTEEGN
     YDIVGNNTPV FFVNDPLKFP DFIHSQKRDP RTHARSQDMQ WDFWSLSPES VHQVTILMSD
     RGIPASYRMM HGFGSHTFKW VNAQGEQFWV KYHFKTNQGI HNLSNELADE LAGKDTDYLQ
     NDLFDAIETG DYPSWTVAVQ LVPYEDGLNY PQDIFDVTKV ISQKDYPLIE IGQMVLDENP
     TNNFEDIQEL AFSPANLVPG IEASPDKLLQ GRLFGYKDAE RYRLGANYEQ LPVNRPKVPV
     HNYERDGAMA QNQATGVNYE PNSQDGPTEV PAAKIHGDQL SGTTGNFSAD PDYYSAAGKL
     YRLLSADEQT RLIENIRMNL GQVTKPEIQI REVKQFYQAD PEYGRRVATS VKLRFSSV
//