[1]	NUCLEOTIDE SEQUENCE [GENOMIC DNA]. STRAIN=FDTP-3; He Z.-Q., Mao Y.-M., Sheng Z.-J., Shen R.-Q.; Submitted (JUL-1992) to the EMBL/GenBank/DDBJ databases.

Comments

CATALYTIC ACTIVITY: Catechol + O₂ = 2-hydroxymuconate semialdehyde.
COFACTOR: Fe(2+) ion.
SIMILARITY: Belongs to the extradiol ring-cleavage dioxygenase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

X67860; CAA48044.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

PIR

JC1324; JC1324.

3D structure databases

ModBase

P31003.

Ontologies

GO:0018577;	Molecular function: catechol 2,3-dioxygenase activity (inferred from electronic annotation from EC).
GO:0008198;	Molecular function: ferrous iron binding (inferred from electronic annotation from InterPro).
GO:0019439;	Biological process: aromatic compound catabolic process (inferred from electronic annotation from UniProtKB-KW).
GO:0055114;	Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.

Family and domain databases

InterPro

IPR017624; Catechol_2-3_dOase.
IPR004360; Glyas_bleo-R_dOase.
IPR000486; Xdiol_dOase_1_2.
Graphical view of domain structure.

Pfam

PF00903; Glyoxalase; 2.
Pfam graphical view of domain structure.

ProDom

PD002334; Gly_diox; 2.
[Domain structure / List of seq. sharing at least 1 domain]

PROSITE

PS00082; EXTRADIOL_DIOXYGENAS; 1.

ProtoNet

P31003.

Other

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Aromatic hydrocarbons catabolism; Dioxygenase; Iron; Metal-binding; Oxidoreductase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 327`	`327`	`Metapyrocatechase.`	`PRO_0000085025`
`METAL`	`159 159`		`Iron (By similarity).`
`METAL`	`221 221`		`Iron (By similarity).`
`METAL`	`272 272`		`Iron (By similarity).`

Sequence information

Length: 327 AA [This is the length of the unprocessed precursor]

Molecular weight: 37419 Da [This is the MW of the unprocessed precursor]

CRC64: F8E7550697798EA7 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MSKNFQEPIF DVAQLAHVEL LSPKLEESIV FFTKYLGMEV TARAGNSVYL RAYEDFYHNT 

        70         80         90        100        110        120 
LKITESAEAG LGHVGWRASS PQALERRVLE LEKSGLGRGW IDGDIGHGKA YQFTTPDGHQ 

       130        140        150        160        170        180 
MEIFFEVEYY KPQPEQKTKL LNRPSKRPAQ GVPVRRLDHI NLMTSNPGVD TQFMIDTLGF 

       190        200        210        220        230        240 
RLREQIRDKG KILGSWISVS NLVHEIAFMQ EPNQEKGKLH HLCYWYGIPQ NLYDLADLLK 

       250        260        270        280        290        300 
DHEYFIEVPP NKHGISQAFC MYVYEPGGNR IELFGDAGYL ITDPTWEPVI WEMEDVPGNG 

       310        320 
DTWIGTAFPD SWWLRGTPVT TKEVVKP

P31003 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools