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UniProtKB/Swiss-Prot entry P32420


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name DHSB_USTMA
Primary accession number P32420
Secondary accession numbers Q12722 Q4PGB9
Integrated into Swiss-Prot on October 1, 1993
Sequence was last modified on October 1, 1993 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 70)
Name and origin of the protein
Protein name Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial [Precursor]
Synonyms EC 1.3.5.1
Iron-sulfur subunit of complex II
Ip
Gene name
Name: SDH2
Synonyms: CBXR
From
Ustilago maydis (Smut fungus) [TaxID: 5270] 
Taxonomy Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina; Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Ustilago.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=ATCC 38509 / 92;
DOI=10.1007/BF00312739; PubMed=1879000 [NCBI, ExPASy, EBI, Israel, Japan]
Keon J.P.R., White G.A., Hargreaves J.A.;
"Isolation, characterization and sequence of a gene conferring resistance to the systemic fungicide carboxin from the maize smut pathogen, Ustilago maydis.";
Curr. Genet. 19:475-481(1991).
[2]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
DOI=10.1007/BF00351470; PubMed=1423716 [NCBI, ExPASy, EBI, Israel, Japan]
Broomfield P.L.E., Hargreaves J.A.;
"A single amino-acid change in the iron-sulphur protein subunit of succinate dehydrogenase confers resistance to carboxin in Ustilago maydis.";
Curr. Genet. 22:117-121(1992).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=521;
DOI=10.1038/nature05248; PubMed=17080091 [NCBI, ExPASy, EBI, Israel, Japan]
Kaemper J., Kahmann R., Boelker M., Ma L.-J., Brefort T., Saville B.J., Banuett F., Kronstad J.W., Gold S.E., Mueller O., Perlin M.H., Woesten H.A.B., de Vries R., Ruiz-Herrera J., Reynaga-Pena C.G., Snetselaar K., McCann M., Perez-Martin J., Feldbruegge M., Basse C.W., Steinberg G., Ibeas J.I., Holloman W., Guzman P., Farman M.L., Stajich J.E., Sentandreu R., Gonzalez-Prieto J.M., Kennell J.C., Molina L., Schirawski J., Mendoza-Mendoza A., Greilinger D., Muench K., Roessel N., Scherer M., Vranes M., Ladendorf O., Vincon V., Fuchs U., Sandrock B., Meng S., Ho E.C.H., Cahill M.J., Boyce K.J., Klose J., Klosterman S.J., Deelstra H.J., Ortiz-Castellanos L., Li W., Sanchez-Alonso P., Schreier P.H., Haeuser-Hahn I., Vaupel M., Koopmann E., Friedrich G., Voss H., Schlueter T., Margolis J., Platt D., Swimmer C., Gnirke A., Chen F., Vysotskaia V., Mannhaupt G., Gueldener U., Muensterkoetter M., Haase D., Oesterheld M., Mewes H.-W., Mauceli E.W., DeCaprio D., Wade C.M., Butler J., Young S.K., Jaffe D.B., Calvo S.E., Nusbaum C., Galagan J.E., Birren B.W.;
"Insights from the genome of the biotrophic fungal plant pathogen Ustilago maydis.";
Nature 444:97-101(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
X62762; CAA44612.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
Z11738; CAA77798.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AACP01000027; EAK81918.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR S26978; S26978.
RefSeq XP_756991.1; -.
3D structure databases
HSSP P07014; 1NEK. [HSSP ENTRY / PDB]
SMR P32420; 52-280.
ModBase P32420.
Family and domain databases
InterPro IPR006058; 2Fe2S_fd_BS.
IPR001450; 4Fe4S_Fe_S_bd.
IPR012675; b-grasp_ferredoxin-like.
IPR001041; Ferredoxin.
IPR012285; Fum_reductase_C.
IPR004489; Succ_DHase/fum_Rdtase_Fe-S.
Graphical view of domain structure.
Gene3D G3DSA:3.10.20.30; Ferredoxin_fold; 1.
G3DSA:1.10.1060.10; Fum_reductase_C; 1.
Pfam PF00111; Fer2; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00384; dhsB; 1.
PROSITE PS00197; 2FE2S_FER_1; 1.
PS51085; 2FE2S_FER_2; 1.
PS00198; 4FE4S_FER_1; 1.
PS51379; 4FE4S_FER_2; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS P32420.
Genome annotation databases
GeneID 3628909; -.
KEGG uma:UM00844.1; -.
Other
ProtoNet P32420.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
2Fe-2S; 3Fe-4S; 4Fe-4S; Complete proteome; Electron transport; Iron; Iron-sulfur; Membrane; Metal-binding; Mitochondrion; Mitochondrion inner membrane; Oxidoreductase; Transit peptide; Transport; Tricarboxylic acid cycle.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
TRANSIT   1     ?        Mitochondrion (Potential). 
CHAIN   ?   295        Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial. PRO_0000010352
DOMAIN   67   144  78     2Fe-2S ferredoxin-type. 
DOMAIN   185   215  31     4Fe-4S ferredoxin-type. 
METAL   106   106        Iron-sulfur 1 (2Fe-2S) (By similarity). 
METAL   111   111        Iron-sulfur 1 (2Fe-2S) (By similarity). 
METAL   114   114        Iron-sulfur 1 (2Fe-2S) (By similarity). 
METAL   126   126        Iron-sulfur 1 (2Fe-2S) (By similarity). 
METAL   195   195        Iron-sulfur 2 (4Fe-4S) (By similarity). 
METAL   198   198        Iron-sulfur 2 (4Fe-4S) (By similarity). 
METAL   201   201        Iron-sulfur 2 (4Fe-4S) (By similarity). 
METAL   205   205        Iron-sulfur 3 (3Fe-4S) (By similarity). 
METAL   252   252        Iron-sulfur 3 (3Fe-4S) (By similarity). 
METAL   258   258        Iron-sulfur 3 (3Fe-4S) (By similarity). 
METAL   262   262        Iron-sulfur 2 (4Fe-4S) (By similarity). 
BINDING   210   210        Ubiquinone; shared with DHSD (By similarity). 
VARIANT   253   253  1     H -> L (in carboxin-resistant mutant). 
Sequence information
Length: 295 AA [This is the length of the unprocessed precursor] Molecular weight: 33282 Da [This is the MW of the unprocessed precursor] CRC64: F374A20BA8F8E7E5 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSLFNVSNGL RTALRPSVAS SSRVAAFSTT AAARLATPTS DNVGSSGKPQ HLKQFKIYRW 

        70         80         90        100        110        120 
NPDKPSEKPR LQSYTLDLNQ TGPMVLDALI KIKNEIDPTL TFRRSCREGI CGSCAMNIDG 

       130        140        150        160        170        180 
VNTLACLCRI DKQNDTKIYP LPHMYIVKDL VPDLTQFYKQ YRSIEPFLKS NNTPSEGEHL 

       190        200        210        220        230        240 
QSPEERRRLD GLYECILCAC CSTSCPSYWW NQDEYLGPAV LMQAYRWMAD SRDDFGEERR 

       250        260        270        280        290 
QKLENTFSLY RCHTIMNCSR TCPKNLNPGK AIAQIKKDMA VGAPKASERP IMASS 

P32420 in FASTA format

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