GO:0005759;	Cellular component: mitochondrial matrix (inferred from electronic annotation from UniProtKB-SubCell).
GO:0004029;	Molecular function: aldehyde dehydrogenase (NAD) activity (inferred from electronic annotation from EC).
GO:0055114;	Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
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Family and domain databases

InterPro

IPR016160; Ald_DHase_CS.
IPR016162; Ald_DHase_N.
IPR015590; Aldehyde_DHase.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.605.10; Aldehyde_dehydrogenase_N; 1.

PANTHER

PTHR11699; Aldehyde_dehyd; 1.

Pfam

PF00171; Aldedh; 1.
Pfam graphical view of domain structure.

PROSITE

PS00070; ALDEHYDE_DEHYDR_CYS; 1.
PS00687; ALDEHYDE_DEHYDR_GLU; 1.

ProtoNet

P32872.

Other

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Mitochondrion; NAD; Oxidoreductase; Transit peptide.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`TRANSIT`	`1 21`	`21`	`Mitochondrion.`
`CHAIN`	`22 511`	`490`	`Aldehyde dehydrogenase 2, mitochondrial.`	`PRO_0000007164`
`NP_BIND`	`274 279`	`6`	`NAD (By similarity).`
`ACT_SITE`	`297 297`		`Proton acceptor (By similarity).`
`ACT_SITE`	`331 331`		`Nucleophile (By similarity).`
`SITE`	`198 198`	`1`	`Transition state stabilizer (By similarity).`

Sequence information

Length: 511 AA [This is the length of the unprocessed precursor]

Molecular weight: 56466 Da [This is the MW of the unprocessed precursor]

CRC64: 70EDAE951B84EE4A [This is a checksum on the sequence]

        10         20         30         40         50         60 
MSKSKTKTDK RNQSSLSRIK LSALHYCMSD AEPSIAYLQD NSAFINNEWH NLVLEKIFPV 

        70         80         90        100        110        120 
YNPSTEEDIT QVSEKSQHDS TEEDITQVSE KSQHDDDKAV VDISERGRLL NILADLIERD 

       130        140        150        160        170        180 
RDILAAIEHL DNGKPFDEAY LLDLASVLKE LRYTAGWADK LHGTLRFAIT IPTFQDLRFL 

       190        200        210        220        230        240 
RYTRHEPVGV CGEIIPWNIP LLMYIWKIGP ALAAGNTVVL KPEELTPLTA LTVATLIKEA 

       250        260        270        280        290        300 
GFPPGVVNVV SGYGPTAGAA CLSHKDNDKL AFTGSTLVGK VVMKAAAKSN LKKVTLELGG 

       310        320        330        340        350        360 
KSPMIVFIDA DLDWAVENAH FGVFFNQGQC CIAQSRITVH ESIYDEIVER DLEKAKKQVL 

       370        380        390        400        410        420 
GNPFESDTRY GPQILKIEFD SIPRLINSAK AEGAKVLCGG GRDDSCVGYY IQPTVFADVT 

       430        440        450        460        470        480 
DEMRIAKEEI FGPVITISRF KSVDEAIKRV DNTKYGLAAY VFTKDKAIRI SAALKAGTVW 

       490        500        510 
VNCVHVASYQ IPFGGNKNSG MGRELGEYGL E

P32872 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools