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UniProtKB/Swiss-Prot entry P34355

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ACOX_CAEEL
Primary accession number P34355
Secondary accession numbers None
Integrated into Swiss-Prot on February 1, 1994
Sequence was last modified on February 1, 1994 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 66)
Name and origin of the protein
Protein name Probable peroxisomal acyl-coenzyme A oxidase
Synonyms Acyl-CoA oxidase
AOX
EC 1.3.3.6
Gene name
ORFNames: C48B4.1
From
Caenorhabditis elegans [TaxID: 6239] 
Taxonomy Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis.
Protein existence 2: Evidence at transcript level;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Bristol N2;
DOI=10.1038/368032a0; PubMed=7906398 [NCBI, ExPASy, EBI, Israel, Japan]
Wilson R., Ainscough R., Anderson K., Baynes C., Berks M., Bonfield J., Burton J., Connell M., Copsey T., Cooper J., Coulson A., Craxton M., Dear S., Du Z., Durbin R., Favello A., Fraser A., Fulton L., Gardner A., Green P., Hawkins T., Hillier L., Jier M., Johnston L., Jones M., Kershaw J., Kirsten J., Laisster N., Latreille P., Lightning J., Lloyd C., Mortimore B., O'Callaghan M., Parsons J., Percy C., Rifken L., Roopra A., Saunders D., Shownkeen R., Sims M., Smaldon N., Smith A., Smith M., Sonnhammer E., Staden R., Sulston J., Thierry-Mieg J., Thomas K., Vaudin M., Vaughan K., Waterston R., Watson A., Weinstock L., Wilkinson-Sproat J., Wohldman P.;
"2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans.";
Nature 368:32-38(1994).
[2]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Bristol N2;
DOI=10.1126/science.282.5396.2012; PubMed=9851916 [NCBI, ExPASy, EBI, Israel, Japan]
The C. elegans sequencing consortium;
"Genome sequence of the nematode C. elegans: a platform for investigating biology.";
Science 282:2012-2018(1998).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
Z29117; CAA82376.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR S40722; S40722.
RefSeq NP_499119.1; -.
UniGene Cel.10702
3D structure databases
HSSP P07872; 1IS2. [HSSP ENTRY / PDB]
ModBase P34355.
Organism-specific databases
WormBase WBGene00008167; C48B4.1.
WormPep C48B4.1; CE00491. [WormPep / WorfDB]
Gene expression databases
ArrayExpress P34355; -.
Ontologies
GO
GO:0005777; Cellular component: peroxisome (inferred from electronic annotation from InterPro).
GO:0003995; Molecular function: acyl-CoA dehydrogenase activity (inferred from electronic annotation from InterPro).
GO:0003997; Molecular function: acyl-CoA oxidase activity (inferred from electronic annotation from InterPro).
GO:0009055; Molecular function: electron carrier activity (inferred from electronic annotation from InterPro).
GO:0050660; Molecular function: FAD binding (inferred from electronic annotation from InterPro).
GO:0006635; Biological process: fatty acid beta-oxidation (inferred from electronic annotation from InterPro).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR006091; Acyl-CoA_DHase/Oxase_M.
IPR012258; Acyl-CoA_oxidase.
IPR002655; Acyl_CoA_ox_C.
IPR013786; AcylCoA_DH/ox_N.
IPR013764; AcylCoA_oxidase/DH_1/2_C.
Graphical view of domain structure.
Gene3D G3DSA:2.40.110.10; Acyl_CoA_DH/ox_M; 1.
G3DSA:1.10.540.10; AcylCoA_DH/ox_N; 1.
G3DSA:1.20.140.10; AcylCoA_DH_1/2_C; 2.
PANTHER PTHR10909:SF11; Acyl-CoA_oxidase; 1.
Pfam PF01756; ACOX; 1.
PF02770; Acyl-CoA_dh_M; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000168; Acyl-CoA_oxidase; 1.
ProtoNet P34355.
Genome annotation databases
Ensembl C48B4.1; Caenorhabditis elegans. [Contig view]
GeneID 176353; -.
KEGG cel:C48B4.1; -.
Other
NextBio 892210; -.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; FAD; Fatty acid metabolism; Flavoprotein; Lipid metabolism; Oxidoreductase; Peroxisome.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   659  659     Probable peroxisomal acyl-coenzyme A oxidase. PRO_0000204688
MOTIF   657   659  3     Microbody targeting signal (Potential). 
Sequence information
Length: 659 AA [This is the length of the unprocessed precursor] Molecular weight: 74714 Da [This is the MW of the unprocessed precursor] CRC64: 5F0D6E92F8CAA5F8 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MPLNKLIQDG DNQDLTDERF KATFDTDALA AVFHGGEDAL KRIRELRDEV TKRWHLFDAL 

        70         80         90        100        110        120 
PGAHRTRAER MEDVSRKLKN LMESVGEFAD FTNNLDMLVI IRDVMGIEGF PLALHNLMFV 

       130        140        150        160        170        180 
PTIQNQADDE QTEWWLMDAL QGKIIGTYAQ TELGHGTNLG AIETTATYDK LTEEFIIHTP 

       190        200        210        220        230        240 
TTTATKWWPG GLGTSCTHVV LVANLIIDTK NYGLHPFFVP IRDRNSYSVM SGVRVGDIGT 

       250        260        270        280        290        300 
KMGVNCVDNG FLAFDNYRIP RRNMLMKHSK VSKEGLYTAP SHPKVGYTTM LYMRSEMIYH 

       310        320        330        340        350        360 
QAYYLAMAMA ISIRYSAVRR QGEIKPGTQE VQILDYQTQQ YRIFPGLARC FAFNTAAATV 

       370        380        390        400        410        420 
RQMTENCIKQ LSHGNSDVLA DLHALSCGLK AVVTHQASQS IDQARQACGG HGYSDASYLP 

       430        440        450        460        470        480 
TLYTCSVGAC TYEGENMVML LQLSKYLMKA AAKAEKGEEM APLVAYLVKP DITETNDKFA 

       490        500        510        520        530        540 
KMLSHFEHIA RHRVMHAYRQ MIEEEKQGIE RDYAFANHSV DWTKAARAHT KLFIARGFVK 

       550        560        570        580        590        600 
SVQEVSDEAV HDVLTTLAEL YLSYELIEMS ADLTANGYLS ESDVQQIRHQ IYDSMRKTRR 

       610        620        630        640        650 
NAVSIVDSFD ICDRELRSVL GRRDGHVYEN LYKWAQMSPL NERNLPHVEK YLKPMTSKL
P34355 in FASTA format

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