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UniProtKB/Swiss-Prot entry P37222

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name MAOC_SOLLC
Primary accession number P37222
Secondary accession numbers None
Integrated into Swiss-Prot on October 1, 1994
Sequence was last modified on October 1, 1994 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 59)
Name and origin of the protein
Protein name NADP-dependent malic enzyme, chloroplastic [Fragment]
Synonyms NADP-ME
EC 1.1.1.40
Gene name None
From
Solanum lycopersicum (Tomato) (Lycopersicon esculentum) [TaxID: 4081] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum; Lycopersicon.
Protein existence 2: Evidence at transcript level;
References
[1]
 NUCLEOTIDE SEQUENCE [MRNA].
STRAIN=cv. Rutgers;
Finger F.L., Knee M., Lagrimini L.M.A.;
"Isolation of a cDNA clone for tomato fruit NADP+ malic enzyme.";
Submitted (JAN-1994) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
L27509; AAA34174.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR T07088; T07088.
3D structure databases
HSSP P40927; 1GQ2. [HSSP ENTRY / PDB]
ModBase P37222.
Ontologies
GO
GO:0009507; Cellular component: chloroplast (inferred from electronic annotation from UniProtKB-KW).
GO:0004473; Molecular function: malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity (inferred from electronic annotation from EC).
GO:0046872; Molecular function: metal ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0051287; Molecular function: NAD binding (inferred from electronic annotation from InterPro).
GO:0006108; Biological process: malate metabolic process (inferred from electronic annotation from InterPro).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR015884; Malic_enzyme_CS.
IPR012301; Malic_N.
IPR012302; Malic_NAD_bd.
IPR001891; Malic_OxRdtase.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
Pfam PF00390; malic; 1.
PF03949; Malic_M; 1.
Pfam graphical view of domain structure.
PRINTS PR00072; MALOXRDTASE.
PROSITE PS00331; MALIC_ENZYMES; 1.
ProtoNet P37222.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Chloroplast; Metal-binding; NAD; NADP; Oxidoreductase; Plastid.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   <1   573  >573     NADP-dependent malic enzyme, chloroplastic. PRO_0000160199
NP_BIND   318   334  17     NADP (By similarity). 
ACT_SITE   123   123        Proton donor (By similarity). 
ACT_SITE   194   194        Proton acceptor (By similarity). 
METAL   265   265        Divalent metal cation (By similarity). 
METAL   266   266        Divalent metal cation (By similarity). 
METAL   289   289        Divalent metal cation (By similarity). 
BINDING   176   176        NAD (By similarity). 
BINDING   289   289        NAD (By similarity). 
BINDING   430   430        NAD (By similarity). 
SITE   289   289  1     Important for activity (By similarity). 
NON_TER   1     1         
Sequence information
Length: 573 AA [This is the length of the partial sequence of the unprocessed precursor] Molecular weight: 63561 Da [This is the MW of the partial sequence of the unprocessed precursor] CRC64: 13846E61206F8E75 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
IRHESTVTGG VQDVYGEDSA TEDQSITPWT LSVASGFSLL RNPHYNKGLA FSERERDTHY 

        70         80         90        100        110        120 
LRGLLPPVVI SHDLQVKKMM NSIRKYDVPL QRYMAMMDLQ EMNERLFYKL LIDNVEELLP 

       130        140        150        160        170        180 
IVYTPTVGEA CQKYGWIFKR PQGLFFSLKE KGKIHEVLKN WPEKKIQVIV VTDGERILGL 

       190        200        210        220        230        240 
GDLGCQGMGI PVGKLSLYSA LGGIRPSACL PVTIDVGQTM KFVDDEFYIG LRQRRATGQE 

       250        260        270        280        290        300 
YSELLDEFMY AVKQNYGEKV LIQFEDFANH NAFNLLAKYG TSHLVFNDDI QGTASVVLAG 

       310        320        330        340        350        360 
LMAALNLVGG SLSEHTFLFL GAGEAGTGIA ELIALEMSKQ TGIPLEETRK KIWMVDSKGL 

       370        380        390        400        410        420 
IVKSRMEMLQ HFKRPWAHDH EPVQELVNAV KSIKPTVLIG SSGAGRTFTK EVVQAMATFN 

       430        440        450        460        470        480 
EKPIIFALSN PTSQSECTAE EAYSWSEGRA IFASGSPFAP VEYNGKVYAS GQANNAYIFP 

       490        500        510        520        530        540 
GFGLGLIISG AIRVHDDMLL VASEALADEV SQENFEKGTH IPPFSNIRKI SAHIAKVAAK 

       550        560        570 
AYELGLATRL PQPKDLVAYA ESCMYSPAYR SYR
P37222 in FASTA format

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