ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry P39633


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name DHE2_BACSU
Primary accession number P39633
Secondary accession numbers Q53548 Q5W7E9
Integrated into Swiss-Prot on February 1, 1995
Sequence was last modified on December 15, 1998 (Sequence version 2)
Annotations were last modified on    September 2, 2008 (Entry version 58)
Name and origin of the protein
Protein name NAD-specific glutamate dehydrogenase
Synonyms NAD-GDH
EC 1.4.1.2
Gene name
Name: rocG
Synonyms: yweB
OrderedLocusNames: BSU37790
ORFNames: ipa-75d
From
Bacillus subtilis [TaxID: 1423] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=168;
PubMed=7934828 [NCBI, ExPASy, EBI, Israel, Japan]
Glaser P., Kunst F., Arnaud M., Coudart M.P., Gonzales W., Hullo M.-F., Ionescu M., Lubochinsky B., Marcelino L., Moszer I., Presecan E., Santana M., Schneider E., Schweizer J., Vertes A., Rapoport G., Danchin A.;
"Bacillus subtilis genome project: cloning and sequencing of the 97 kb region from 325 degrees to 333 degrees.";
Mol. Microbiol. 10:371-384(1993).
[2]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=ISW1214;
Khan M.H., Itoh K., Kim H., Ashida H., Ishikawa T., Shibata H., Sawa Y.;
"Low thermostability of the NAD+ specific glutamate dehydrogenase from Bacillus subtilis ISW1214: cloning, purification and characterization.";
Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=168;
DOI=10.1038/36786; PubMed=9384377 [NCBI, ExPASy, EBI, Israel, Japan]
Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.;
"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.";
Nature 390:249-256(1997).
[4]
NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 418-424.
DOI=10.1007/BF02191600; PubMed=7565595 [NCBI, ExPASy, EBI, Israel, Japan]
Klingel U., Miller C.M., North A.K., Stockley P.G., Baumberg S.;
"A binding site for activation by the Bacillus subtilis AhrC protein, a repressor/activator of arginine metabolism.";
Mol. Gen. Genet. 248:329-340(1995).
[5]
CHARACTERIZATION.
PubMed=9829940 [NCBI, ExPASy, EBI, Israel, Japan]
Belitsky B.R., Sonenshein A.L.;
"Role and regulation of Bacillus subtilis glutamate dehydrogenase genes.";
J. Bacteriol. 180:6298-6305(1998).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
X73124; CAA51631.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AB194695; BAD69594.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
Z99123; CAB15806.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
S79622; -; NOT_ANNOTATED_CDS; Genomic_DNA.[EMBL / GenBank / DDBJ]
PIR A70055; A70055.
RefSeq NP_391659.1; -.
3D structure databases
HSSP P80319; 1GTM. [HSSP ENTRY / PDB]
ModBase P39633.
Enzyme and pathway databases
BioCyc BSUB224308:BSU3776-MON; -.
Organism-specific databases
SubtiList BG10621; rocG. [Micado]
Family and domain databases
InterPro IPR006095; Glu/Leu/Phe/Val_DHase.
IPR006096; Glu/Leu/Phe/Val_DHase_C.
IPR006097; Glu/Leu/Phe/Val_DHase_dimer.
IPR014362; Glu_DHase.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR11606:SF2; GLFV_DH; 1.
Pfam PF00208; ELFV_dehydrog; 1.
PF02812; ELFV_dehydrog_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000185; Glu_DH; 1.
PRINTS PR00082; GLFDHDRGNASE.
PROSITE PS00074; GLFV_DEHYDROGENASE; 1.
BLOCKS P39633.
Genome annotation databases
GeneID 937066; -.
GenomeReviews AL009126_GR; BSU37790.
KEGG bsu:BSU37790; -.
NMPDR fig|224308.1.peg.3785; -.
Phylogenomic databases
HOGENOM P39633; -.
Genome annotation databases
CMR P39633; BSU37790.
Other
ProtoNet P39633.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   424  424     NAD-specific glutamate dehydrogenase. PRO_0000182735
ACT_SITE   116   116        By similarity. 
CONFLICT   324   324        R -> A (in Ref. 2; BAD69594). 
CONFLICT   419   424        RFRGWV -> FPRMGLI (in Ref. 1; CAA51631). 
Sequence information
Length: 424 AA [This is the length of the unprocessed precursor] Molecular weight: 46638 Da [This is the MW of the unprocessed precursor] CRC64: DFE311C72BEA8091 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSAKQVSKDE EKEALNLFLS TQTIIKEALR KLGYPGDMYE LMKEPQRMLT VRIPVKMDNG 

        70         80         90        100        110        120 
SVKVFTGYRS QHNDAVGPTK GGVRFHPEVN EEEVKALSIW MTLKCGIANL PYGGGKGGII 

       130        140        150        160        170        180 
CDPRTMSFGE LERLSRGYVR AISQIVGPTK DIPAPDVYTN SQIMAWMMDE YSRLREFDSP 

       190        200        210        220        230        240 
GFITGKPLVL GGSQGRETAT AQGVTICIEE AVKKKGIKLQ NARIIIQGFG NAGSFLAKFM 

       250        260        270        280        290        300 
HDAGAKVIGI SDANGGLYNP DGLDIPYLLD KRDSFGMVTN LFTDVITNEE LLEKDCDILV 

       310        320        330        340        350        360 
PAAISNQITA KNAHNIQASI VVERANGPTT IDATKILNER GVLLVPDILA SAGGVTVSYF 

       370        380        390        400        410        420 
EWVQNNQGYY WSEEEVAEKL RSVMVSSFET IYQTAATHKV DMRLAAYMTG IRKSAEASRF 


RGWV 

P39633 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
 Hosted by ca flag CBR Canada Mirror sites: Australia  Brazil  China  Korea  Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!