ID   QOR_SALTY               Reviewed;         327 AA.
AC   P40783;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   13-DEC-2001, sequence version 2.
DT   25-NOV-2008, entry version 54.
DE   RecName: Full=Quinone oxidoreductase;
DE            EC=1.6.5.5;
DE   AltName: Full=NADPH:quinone reductase;
DE   AltName: Full=Zeta-crystallin homolog protein;
GN   Name=qor; OrderedLocusNames=STM4245;
OS   Salmonella typhimurium.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=602;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   MEDLINE=21534948; PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M.,
RA   Waterston R., Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium
RT   LT2.";
RL   Nature 413:852-856(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-168.
RX   MEDLINE=88227847; PubMed=2836367;
RA   Wong A., Kean L., Maurer R.;
RT   "Sequence of the dnaB gene of Salmonella typhimurium.";
RL   J. Bacteriol. 170:2668-2675(1988).
CC   -!- CATALYTIC ACTIVITY: NADPH + 2 quinone = NADP(+) + 2 semiquinone.
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. Quinone oxidoreductase subfamily.
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DR   EMBL; AE008898; AAL23069.1; -; Genomic_DNA.
DR   EMBL; J03390; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_463110.1; -.
DR   HSSP; P28304; 1QOR.
DR   SMR; P40783; 2-327.
DR   GeneID; 1255771; -.
DR   GenomeReviews; AE006468_GR; STM4245.
DR   KEGG; stm:STM4245; -.
DR   NMPDR; fig|99287.1.peg.4083; -.
DR   StyGene; SG10511; qor.
DR   HOGENOM; P40783; -.
DR   BioCyc; STYP99287:STM4245-MON; -.
DR   GO; GO:0003960; F:NADPH:quinone reductase activity; IEA:EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0055114; P:oxidation reduction; IEA:InterPro.
DR   InterPro; IPR013154; AlcDHase_GroES-like.
DR   InterPro; IPR002085; AlcDHase_SF_Zn.
DR   InterPro; IPR013149; AlcDHase_Zn-bd.
DR   InterPro; IPR016040; NAD(P)-bd.
DR   InterPro; IPR002364; Quin_OxRdtase/zeta-crystal_CS.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   PANTHER; PTHR11695; ADH_Sf_Zn; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   PROSITE; PS01162; QOR_ZETA_CRYSTAL; 1.
PE   3: Inferred from homology;
KW   Complete proteome; NADP; Oxidoreductase.
FT   CHAIN         1    327       Quinone oxidoreductase.
FT                                /FTId=PRO_0000160902.
FT   CONFLICT     92     92       L -> V (in Ref. 2; J03390).
FT   CONFLICT    148    148       A -> R (in Ref. 2; J03390).
SQ   SEQUENCE   327 AA;  35151 MW;  602F4CB6E6A805F1 CRC64;
     MATRIEFHKH GGPEVLQTVE FTPAEPAEHE IQVENKAIGI NFIDTYIRSG LYPPPSLPAG
     LGTEAAGVVS KVGNGVEHIR VGDRVVYAQS TLGAYSSVHN VTADKAAILP DAISFEQAAA
     SFLKGLTVFY LLRKTYEVKP DEPFLFHAAA GGVGLIACQW AKALGAKLIG TVGSAQKAQR
     ALDAGAWQVI NYREESIVER VKEITGGKKV RVVYDSVGKD TWEASLDCLQ RRGLMVSFGN
     ASGPVTGVNL GILNQKGSLY ATRPSLQGYI TTREELTEAS NELFSLIASG VIKVDVAENQ
     RYALKDARRA HEVLESRATQ GSSLLIP
//