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UniProtKB/Swiss-Prot entry P40837

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name BR2EA_RANES
Primary accession number P40837
Secondary accession numbers None
Integrated into Swiss-Prot on February 1, 1995
Sequence was last modified on February 1, 1995 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 39)
Name and origin of the protein
Protein name Brevinin-2Ea
Synonyms None
Gene name None
From
Rana esculenta (Edible frog) [TaxID: 8401] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana; Pelophylax.
Protein existence 1: Evidence at protein level;
References
[1]
 PROTEIN SEQUENCE, AND DISULFIDE BOND.
TISSUE=Skin secretion;
PubMed=8163497 [NCBI, ExPASy, EBI, Israel, Japan]
Simmaco M., Mignogna G., Barra D., Bossa F.;
"Antimicrobial peptides from skin secretions of Rana esculenta. Molecular cloning of cDNAs encoding esculentin and brevinins and isolation of new active peptides.";
J. Biol. Chem. 269:11956-11961(1994).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
PIR A55998; A55998.
3D structure databases
ModBase P40837.
Ontologies
GO
GO:0005576; Cellular component: extracellular region (inferred from electronic annotation from InterPro).
GO:0019835; Biological process: cytolysis (inferred from electronic annotation from UniProtKB-KW).
GO:0042742; Biological process: defense response to bacterium (inferred from electronic annotation from UniProtKB-KW).
GO:0019836; Biological process: hemolysis by symbiont of host red blood cells (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR012521; Antimicrobial_2.
Graphical view of domain structure.
Pfam PF08023; Antimicrobial_2; 1.
Pfam graphical view of domain structure.
ProtoNet P40837.
Phylogenomic databases
HOVERGEN P40837; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amphibian defense peptide; Antibiotic; Antimicrobial; Cytolysis; Direct protein sequencing; Hemolysis; Secreted.
Features
SEVIEWER logo Feature table viewer
KeyFrom  To Length Description FTId
PEPTIDE   1   33  33     Brevinin-2Ea. PRO_0000044643
DISULFID   27   33         
Sequence information
Length: 33 AA [This is the length of the unprocessed precursor] Molecular weight: 3245 Da [This is the MW of the unprocessed precursor] CRC64: 4C940BDE699FF616 [This is a checksum on the sequence] 
        10         20         30 
GILDTLKNLA ISAAKGAAQG LVNKASCKLS GQC
P40837 in FASTA format

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