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UniProtKB/Swiss-Prot entry P41816


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name OYE3_YEAST
Primary accession number P41816
Secondary accession numbers None
Integrated into Swiss-Prot on November 1, 1995
Sequence was last modified on January 23, 2007 (Sequence version 2)
Annotations were last modified on    November 25, 2008 (Entry version 73)
Name and origin of the protein
Protein name NADPH dehydrogenase 3
Synonyms EC 1.6.99.1
Old yellow enzyme 3
Gene name
Name: OYE3
OrderedLocusNames: YPL171C
ORFNames: P2291
From
Saccharomyces cerevisiae (Baker's yeast) [TaxID: 4932] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND MASS SPECTROMETRY.
STRAIN=RZ49-1;
DOI=10.1074/jbc.270.5.1983; PubMed=7836424 [NCBI, ExPASy, EBI, Israel, Japan]
Niino Y.S., Chakraborty S., Brown B.J., Massey V.;
"A new old yellow enzyme of Saccharomyces cerevisiae.";
J. Biol. Chem. 270:1983-1991(1995).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 204511 / S288c / AB972;
PubMed=9169875 [NCBI, ExPASy, EBI, Israel, Japan]
Bussey H., Storms R.K., Ahmed A., Albermann K., Allen E., Ansorge W., Araujo R., Aparicio A., Barrell B.G., Badcock K., Benes V., Botstein D., Bowman S., Brueckner M., Carpenter J., Cherry J.M., Chung E., Churcher C.M., Coster F., Davis K., Davis R.W., Dietrich F.S., Delius H., DiPaolo T., Dubois E., Duesterhoeft A., Duncan M., Floeth M., Fortin N., Friesen J.D., Fritz C., Goffeau A., Hall J., Hebling U., Heumann K., Hilbert H., Hillier L.W., Hunicke-Smith S., Hyman R.W., Johnston M., Kalman S., Kleine K., Komp C., Kurdi O., Lashkari D., Lew H., Lin A., Lin D., Louis E.J., Marathe R., Messenguy F., Mewes H.-W., Mirtipati S., Moestl D., Mueller-Auer S., Namath A., Nentwich U., Oefner P., Pearson D., Petel F.X., Pohl T.M., Purnelle B., Rajandream M.A., Rechmann S., Rieger M., Riles L., Roberts D., Schaefer M., Scharfe M., Scherens B., Schramm S., Schroeder M., Sdicu A.-M., Tettelin H., Urrestarazu L.A., Ushinsky S., Vierendeels F., Vissers S., Voss H., Walsh S.V., Wambutt R., Wang Y., Wedler E., Wedler H., Winnett E., Zhong W.-W., Zollner A., Vo D.H., Hani J.;
"The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.";
Nature 387:103-105(1997).
[3]
NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-181.
STRAIN=ATCC 204511 / S288c / AB972;
DOI=10.1002/(SICI)1097-0061(199611)12:14<1483::AID-YEA34>3.3.CO;2-F; PubMed=8948103 [NCBI, ExPASy, EBI, Israel, Japan]
Purnelle B., Coster F., Goffeau A.;
"The sequence of 55 kb on the left arm of yeast chromosome XVI identifies a small nuclear RNA, a new putative protein kinase and two new putative regulators.";
Yeast 12:1483-1492(1996).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
L29279; AAA64522.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
Z73526; CAA97877.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
Z73527; CAA97878.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
X96770; CAA65573.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR A55569; A55569.
RefSeq NP_015154.1; -.
3D structure databases
HSSP Q02899; 1OYC. [HSSP ENTRY / PDB]
SMR P41816; 3-399.
ModBase P41816.
Protein-protein interaction databases
DIP DIP:6338N; -.
IntAct P41816; -.
Organism-specific databases
CYGD YPL171c; -.
SGD S000006092; OYE3.
Yeast-GFP YPL171C.
Gene expression databases
ArrayExpress P41816; -.
GermOnline YPL171C; Saccharomyces cerevisiae.
Ontologies
GO
GO:0010181; Molecular function: FMN binding (inferred from electronic annotation from InterPro).
GO:0003959; Molecular function: NADPH dehydrogenase activity (inferred from electronic annotation from EC).
GO:0005515; Molecular function: protein binding (inferred from physical interaction from IntAct).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
GO:0009636; Biological process: response to toxin (inferred from expression pattern from SGD).
QuickGo view.
Family and domain databases
InterPro IPR013785; Aldolase_TIM.
IPR001155; OxRdtase_FMN_N.
Graphical view of domain structure.
Gene3D G3DSA:3.20.20.70; Aldolase_TIM; 1.
Pfam PF00724; Oxidored_FMN; 1.
Pfam graphical view of domain structure.
ProtoNet P41816.
Proteomic databases
PeptideAtlas P41816; -.
Genome annotation databases
Ensembl YPL171C; Saccharomyces cerevisiae. [Contig view]
GeneID 855932; -.
GenomeReviews U00094_GR; YPL171C.
KEGG sce:YPL171C; -.
NMPDR fig|4932.3.peg.6283; -.
Phylogenomic databases
HOGENOM P41816; -.
Other
LinkHub P41816; -.
NextBio 980675; -.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Flavoprotein; FMN; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
INIT_MET   1     1        Removed (By similarity). 
CHAIN   2   400  399     NADPH dehydrogenase 3. PRO_0000194475
ACT_SITE   197   197        Proton donor (By similarity). 
BINDING   38    38        FMN (By similarity). 
BINDING   192   192        FMN (By similarity). 
BINDING   192   192        Substrate (By similarity). 
BINDING   195   195        Substrate (By similarity). 
BINDING   244   244        FMN (By similarity). 
BINDING   349   349        FMN (By similarity). 
BINDING   376   376        Substrate (By similarity). 
Sequence information
Length: 400 AA [This is the length of the unprocessed precursor] Molecular weight: 44920 Da [This is the MW of the unprocessed precursor] CRC64: CC66CAC4B0748FE1 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MPFVKGFEPI SLRDTNLFEP IKIGNTQLAH RAVMPPLTRM RATHPGNIPN KEWAAVYYGQ 

        70         80         90        100        110        120 
RAQRPGTMII TEGTFISPQA GGYDNAPGIW SDEQVAEWKN IFLAIHDCQS FAWVQLWSLG 

       130        140        150        160        170        180 
WASFPDVLAR DGLRYDCASD RVYMNATLQE KAKDANNLEH SLTKDDIKQY IKDYIHAAKN 

       190        200        210        220        230        240 
SIAAGADGVE IHSANGYLLN QFLDPHSNKR TDEYGGTIEN RARFTLEVVD ALIETIGPER 

       250        260        270        280        290        300 
VGLRLSPYGT FNSMSGGAEP GIIAQYSYVL GELEKRAKAG KRLAFVHLVE PRVTDPSLVE 

       310        320        330        340        350        360 
GEGEYSEGTN DFAYSIWKGP IIRAGNYALH PEVVREQVKD PRTLIGYGRF FISNPDLVYR 

       370        380        390        400 
LEEGLPLNKY DRSTFYTMSA EGYTDYPTYE EAVDLGWNKN 

P41816 in FASTA format

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