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UniProtKB/Swiss-Prot entry P42958


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name TTUC_BACSU
Primary accession number P42958
Secondary accession number O31481
Integrated into Swiss-Prot on November 1, 1995
Sequence was last modified on August 4, 2003 (Sequence version 3)
Annotations were last modified on    November 25, 2008 (Entry version 60)
Name and origin of the protein
Protein name Probable tartrate dehydrogenase/decarboxylase
Synonyms TDH
EC 1.1.1.93
EC 4.1.1.73
D-malate dehydrogenase [decarboxylating]
EC 1.1.1.83
Gene name
Name: ycsA
OrderedLocusNames: BSU04000
From
Bacillus subtilis [TaxID: 1423] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=168;
PubMed=8574415 [NCBI, ExPASy, EBI, Israel, Japan]
Akagawa E., Kurita K., Sugawara T., Nakamura K., Kasahara Y., Ogasawara N., Yamane K.;
"Determination of a 17,484 bp nucleotide sequence around the 39 degrees region of the Bacillus subtilis chromosome and similarity analysis of the products of putative ORFs.";
Microbiology 141:3241-3245(1995).
[2]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=168;
PubMed=8969502 [NCBI, ExPASy, EBI, Israel, Japan]
Yamane K., Kumano M., Kurita K.;
"The 25 degrees-36 degrees region of the Bacillus subtilis chromosome: determination of the sequence of a 146 kb segment and identification of 113 genes.";
Microbiology 142:3047-3056(1996).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=168;
DOI=10.1038/36786; PubMed=9384377 [NCBI, ExPASy, EBI, Israel, Japan]
Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.;
"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.";
Nature 390:249-256(1997).
[4]
SEQUENCE REVISION.
DOI=10.1101/gr.9.11.1116; PubMed=10568751 [NCBI, ExPASy, EBI, Israel, Japan]
Medigue C., Rose M., Viari A., Danchin A.;
"Detecting and analyzing DNA sequencing errors: toward a higher quality of the Bacillus subtilis genome sequence.";
Genome Res. 9:1116-1127(1999).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
D38161; BAA07352.1; ALT_FRAME; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
D50453; BAA09031.1; ALT_FRAME; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
Z99106; CAB12208.2; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR A69765; A69765.
RefSeq NP_388282.2; -.
3D structure databases
HSSP P00351; 1WAL. [HSSP ENTRY / PDB]
ModBase P42958.
Enzyme and pathway databases
BioCyc BSUB224308:BSU0401-MON; -.
Organism-specific databases
SubtiList BG11222; ycsA. [Micado]
Ontologies
GO
GO:0046553; Molecular function: D-malate dehydrogenase (decarboxylating) activity (inferred from electronic annotation from EC).
GO:0051287; Molecular function: NAD binding (inferred from electronic annotation from InterPro).
GO:0050319; Molecular function: tartrate decarboxylase activity (inferred from electronic annotation from EC).
GO:0009027; Molecular function: tartrate dehydrogenase activity (inferred from electronic annotation from InterPro).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR001804; IsoCit_IM_DHase.
IPR011829; TTC_DH.
Graphical view of domain structure.
Gene3D G3DSA:3.40.718.10; IDH_IMDH; 1.
PANTHER PTHR11835; IDH_IMDH_dimeric; 1.
PTHR11835:SF8; TTC_DH; 1.
Pfam PF00180; Iso_dh; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR02089; TTC; 1.
PROSITE PS00470; IDH_IMDH; 1.
ProtoNet P42958.
Genome annotation databases
GeneID 938262; -.
GenomeReviews AL009126_GR; BSU04000.
KEGG bsu:BSU04000; -.
Phylogenomic databases
HOGENOM P42958; -.
Genome annotation databases
CMR P42958; BSU04000.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Lyase; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   354  354     Probable tartrate dehydrogenase/decarboxylase. PRO_0000083820
CONFLICT   143   143        G -> V (in Ref. 1 and 2). 
Sequence information
Length: 354 AA [This is the length of the unprocessed precursor] Molecular weight: 38824 Da [This is the MW of the unprocessed precursor] CRC64: A3BBCD9F2221E32F [This is a checksum on the sequence]
        10         20         30         40         50         60 
MTMKQFEIAA IPGDGVGKEV VAAAEKVLHT AAEVHGGLSF SFTAFPWSCD YYLEHGKMMP 

        70         80         90        100        110        120 
EDGIHTLTQF EAVFLGAVGN PKLVPDHISL WGLLLKIRRE LELSINMRPA KQMAGITSPL 

       130        140        150        160        170        180 
LHPNDFDFVV IRENSEGEYS EVGGRIHRGD DEIAIQNAVF TRKATERVMR FAFELAKKRR 

       190        200        210        220        230        240 
SHVTSATKSN GIYHAMPFWD EVFQQTAADY SGIETSSQHI DALAAFFVTR PETFDVIVAS 

       250        260        270        280        290        300 
KLFGDILTDI SSSLMESIGI APPANINPSG KYPSMFEPVH GSAPDIAGQG LANPIGQIWT 

       310        320        330        340        350 
AKLMLDHFGE EELGAKILDV MEQVTADGIK TRDIGGQSTT AEVTDEICSR LRKL 

P42958 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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