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UniProtKB/Swiss-Prot entry P45575


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name DSVB_DESVH
Primary accession number P45575
Secondary accession numbers None
Integrated into Swiss-Prot on November 1, 1995
Sequence was last modified on January 23, 2007 (Sequence version 3)
Annotations were last modified on    July 22, 2008 (Entry version 57)
Name and origin of the protein
Protein name Sulfite reductase, dissimilatory-type subunit beta
Synonyms EC 1.8.99.3
Desulfoviridin subunit beta
Hydrogensulfite reductase subunit beta
Gene name
Name: dsvB
OrderedLocusNames: DVU_0403
From
Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / NCIMB 8303) [TaxID: 882] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Deltaproteobacteria; Desulfovibrionales; Desulfovibrionaceae; Desulfovibrio.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
PubMed=7887608 [NCBI, ExPASy, EBI, Israel, Japan]
Karkhoff-Schweizer R.R., Huber D.P.W., Voordouw G.;
"Conservation of the genes for dissimilatory sulfite reductase from Desulfovibrio vulgaris and Archaeoglobus fulgidus allows their detection by PCR.";
Appl. Environ. Microbiol. 61:290-296(1995).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1038/nbt959; PubMed=15077118 [NCBI, ExPASy, EBI, Israel, Japan]
Heidelberg J.F., Seshadri R., Haveman S.A., Hemme C.L., Paulsen I.T., Kolonay J.F., Eisen J.A., Ward N.L., Methe B.A., Brinkac L.M., Daugherty S.C., DeBoy R.T., Dodson R.J., Durkin A.S., Madupu R., Nelson W.C., Sullivan S.A., Fouts D.E., Haft D.H., Selengut J., Peterson J.D., Davidsen T.M., Zafar N., Zhou L., Radune D., Dimitrov G., Hance M., Tran K., Khouri H.M., Gill J., Utterback T.R., Feldblyum T.V., Wall J.D., Voordouw G., Fraser C.M.;
"The genome sequence of the anaerobic, sulfate-reducing bacterium Desulfovibrio vulgaris Hildenborough.";
Nat. Biotechnol. 22:554-559(2004).
[3]
PROTEIN SEQUENCE OF 2-16.
PubMed=1555572 [NCBI, ExPASy, EBI, Israel, Japan]
Pierik A.J., Duyvis M.G., van Helvoort J.M.L.M., Wolbert R.B.G., Hagen W.R.;
"The third subunit of desulfoviridin-type dissimilatory sulfite reductases.";
Eur. J. Biochem. 205:111-115(1992).
Comments
  • FUNCTION: Catalyzes the reduction of sulfite to sulfide. This is the terminal oxidation reaction in sulfate respiration, a process catalyzed by the sulfate-reducing bacteria.
  • CATALYTIC ACTIVITY: (O3S.S.SO3)2- + acceptor + 2 H2O + OH- = 3 HSO3- + reduced acceptor.
  • COFACTOR: Binds 1 4Fe-4S cluster per subunit.
  • COFACTOR: Binds 2 sirohemes per subunit.
  • SUBUNIT: Heterohexamer of two alpha, two beta and two gamma subunits.
  • SIMILARITY: Contains 1 4Fe-4S ferredoxin-type domain.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
U16723; AAA70108.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AE017285; AAS94886.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR S21238; S21238.
RefSeq YP_009627.1; -.
3D structure databases
ModBase P45575.
Enzyme and pathway databases
BioCyc DVUL882:DVU_0403-MON; -.
MetaCyc:MON-12512; -.
Family and domain databases
InterPro IPR001450; 4Fe4S_Fe_S_bd.
IPR011808; DsrB.
IPR006067; Nir_Sir_4Fe4S.
IPR005117; NiRdtase/SiRdtase_haem-b_fer.
Graphical view of domain structure.
Pfam PF00037; Fer4; 1.
PF01077; NIR_SIR; 1.
PF03460; NIR_SIR_ferr; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR02066; dsrB; 1.
PROSITE PS00198; 4FE4S_FER_1; 1.
PS51379; 4FE4S_FER_2; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS P45575.
Genome annotation databases
GeneID 2796153; -.
GenomeReviews AE017285_GR; DVU_0403.
KEGG dvu:DVU0403; -.
TIGR DVU_0403; -.
Phylogenomic databases
HOGENOM P45575; -.
Other
ProtoNet P45575.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
4Fe-4S; Complete proteome; Direct protein sequencing; Iron; Iron-sulfur; Metal-binding; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
INIT_MET   1     1        Removed. 
CHAIN   2   381  380     Sulfite reductase, dissimilatory-type subunit beta. PRO_0000080032
DOMAIN   249   276  28     4Fe-4S ferredoxin-type. 
METAL   231   231        Iron-sulfur (4Fe-4S) (Potential). 
METAL   258   258        Iron-sulfur (4Fe-4S) (Potential). 
METAL   261   261        Iron-sulfur (4Fe-4S) (Potential). 
METAL   264   264        Iron-sulfur (4Fe-4S) (Potential). 
Sequence information
Length: 381 AA [This is the length of the unprocessed precursor] Molecular weight: 42519 Da [This is the MW of the unprocessed precursor] CRC64: 678A04F716050D63 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MAFISSGYNP EKPMANRITD IGPRKFDEFF PPVIAKNFGS WLYHEILEPG VLMHVAESGD 

        70         80         90        100        110        120 
KVYTVRVGAA RLMSITHIRE MCDIADKYCG GHLRFTTRNN VEFMVADEAS LKALKEDLAS 

       130        140        150        160        170        180 
RKFDGGSLKF PIGGTGAGVS NIVHTQGWVH CHTPATDASG PVKAIMDEVF EDFQSMRLPA 

       190        200        210        220        230        240 
PVRISLACCI NMCGAVHCSD IGVVGIHRKP PMIDHEWTDQ LCEIPLAVAS CPTAAVRPTK 

       250        260        270        280        290        300 
LEIGDKKVNT IAIKNERCMY CGNCYTMCPA LPISDGEGDG VVIMVGGKVS NRISMPKFSK 

       310        320        330        340        350        360 
VVVAYIPNEP PRWPSLTKTI KHIIEVYSAN AYKYERLGEW AERIGWERFF SLTGLEFSHH 

       370        380 
LIDDFRDPAY YTWRQSTQFK F 

P45575 in FASTA format

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