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UniProtKB/Swiss-Prot entry P46329


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ALDH3_BACSU
Primary accession number P46329
Secondary accession numbers None
Integrated into Swiss-Prot on November 1, 1995
Sequence was last modified on November 1, 1995 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 57)
Name and origin of the protein
Protein name Probable aldehyde dehydrogenase aldX
Synonym EC 1.2.1.3
Gene name
Name: aldX
Synonyms: yxaS, yxbE
OrderedLocusNames: BSU39860
ORFNames: VE7FR
From
Bacillus subtilis [TaxID: 1423] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=168 / BGSC1A1;
DOI=10.1093/dnares/2.2.61; PubMed=7584049 [NCBI, ExPASy, EBI, Israel, Japan]
Yoshida K., Seki S., Fujimura M., Miwa Y., Fujita Y.;
"Cloning and sequencing of a 36-kb region of the Bacillus subtilis genome between the gnt and iol operons.";
DNA Res. 2:61-69(1995).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=168;
DOI=10.1038/36786; PubMed=9384377 [NCBI, ExPASy, EBI, Israel, Japan]
Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.;
"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.";
Nature 390:249-256(1997).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AB005554; BAA21599.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
Z99124; CAB16022.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR B69584; B69584.
RefSeq NP_391865.1; -.
3D structure databases
HSSP P11883; 1AD3. [HSSP ENTRY / PDB]
ModBase P46329.
Enzyme and pathway databases
BioCyc BSUB224308:BSU3982-MON; -.
Organism-specific databases
SubtiList BG11355; aldX. [Micado]
Ontologies
GO
GO:0004029; Molecular function: aldehyde dehydrogenase (NAD) activity (inferred from electronic annotation from EC).
QuickGo view.
Family and domain databases
InterPro IPR016160; Ald_DHase_CS.
IPR016162; Ald_DHase_N.
IPR012394; Ald_DHase_NAD(P).
IPR015590; Aldehyde_DHase.
Graphical view of domain structure.
Gene3D G3DSA:3.40.605.10; Aldehyde_dehydrogenase_N; 1.
PANTHER PTHR11699; Aldehyde_dehyd; 1.
PTHR11699:SF15; ALDH; 1.
Pfam PF00171; Aldedh; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF036492; ALDH; 1.
PROSITE PS00070; ALDEHYDE_DEHYDR_CYS; 1.
PS00687; ALDEHYDE_DEHYDR_GLU; 1.
BLOCKS P46329.
Genome annotation databases
GeneID 937653; -.
GenomeReviews AL009126_GR; BSU39860.
KEGG bsu:BSU39860; -.
NMPDR fig|224308.1.peg.3991; -.
Phylogenomic databases
HOGENOM P46329; -.
Genome annotation databases
CMR P46329; BSU39860.
Other
ProtoNet P46329.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   445  445     Probable aldehyde dehydrogenase aldX. PRO_0000056446
ACT_SITE   214   214        By similarity. 
ACT_SITE   248   248        By similarity. 
Sequence information
Length: 445 AA [This is the length of the unprocessed precursor] Molecular weight: 49570 Da [This is the MW of the unprocessed precursor] CRC64: D567A95BE7763E80 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MEQQVKDDIQ RVFQLQKKQQ KALRASTAEQ RREKLQRFLD SVIAHEEEII EAIRKDVRKP 

        70         80         90        100        110        120 
YHEVKKAEIE GTKKAIRDNM NNLEQWMAPK EVGSSLSPDA NGILMYEPKG VTLILGPWNY 

       130        140        150        160        170        180 
PFMLTMAPLA ASLAAGNSAI VKLSDFTMNT SNIAAKVIRD AFNEKEVAIF EGEVEVATEL 

       190        200        210        220        230        240 
LDQPFDHIFF TGSTNVGKIV MTAAAKHLAS VTLELGGKSP TIIDSEYDLM DAAKKIAVGK 

       250        260        270        280        290        300 
FVNAGQTCIA PDYLFIKKDV QDRFAGILQT VVNAGFMEDD HTPDRSKFTQ IVNDRNFNRV 

       310        320        330        340        350        360 
KDLFDDAIER GAEVVFGGVF DASDRTISPT VLKNVTPDMK IMQEEIFASI LPMMNYEDID 

       370        380        390        400        410        420 
EVIDYVNDRD KPLALYVFSK NQDLIDNVLQ HTTSGNAAIN DVVVHFSDVN LPFGGVNTSG 

       430        440 
IGSYHGVYGF KEFSHEKGVF IQAAE 

P46329 in FASTA format

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