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UniProtKB/Swiss-Prot entry P47470


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name DYR_MYCGE
Primary accession number P47470
Secondary accession numbers None
Integrated into Swiss-Prot on February 1, 1996
Sequence was last modified on February 1, 1996 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 45)
Name and origin of the protein
Protein name Dihydrofolate reductase
Synonym EC 1.5.1.3
Gene name
Name: folA
Synonyms: dhfR
OrderedLocusNames: MG228
From
Mycoplasma genitalium [TaxID: 2097] [HAMAP proteome]
Taxonomy Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 33530 / G-37 / NCTC 10195;
PubMed=7569993 [NCBI, ExPASy, EBI, Israel, Japan]
Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A., Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M., Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L., Nguyen D.T., Utterback T.R., Saudek D.M., Phillips C.A., Merrick J.M., Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S., Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C.;
"The minimal gene complement of Mycoplasma genitalium.";
Science 270:397-403(1995).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
L43967; AAC71449.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR B64225; B64225.
RefSeq NP_072894.1; -.
3D structure databases
HSSP P00374; 1KMV. [HSSP ENTRY / PDB]
ModBase P47470.
Enzyme and pathway databases
BioCyc MGEN243273:MG_228-MON; -.
Family and domain databases
InterPro IPR012259; DHFR.
IPR001796; DHFR_reg.
Graphical view of domain structure.
PANTHER PTHR11549:SF1; DHFR; 1.
Pfam PF00186; DHFR_1; 1.
Pfam graphical view of domain structure.
PRINTS PR00070; DHFR.
PROSITE PS00075; DHFR_1; 1.
PS51330; DHFR_2; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS P47470.
Genome annotation databases
GeneID 875311; -.
GenomeReviews L43967_GR; MG228.
KEGG mge:MG_228; -.
TIGR MG228; -.
Phylogenomic databases
HOGENOM P47470; -.
Other
ProtoNet P47470.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; NADP; One-carbon metabolism; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom To Length Description FTId
CHAIN   1   160  160     Dihydrofolate reductase. PRO_0000186395
DOMAIN   1   160  160     DHFR. 
Sequence information
Length: 160 AA [This is the length of the unprocessed precursor] Molecular weight: 18966 Da [This is the MW of the unprocessed precursor] CRC64: BE46EBAE24DDBE13 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MLIAIWAMTQ EGLIGNNNTL PWMIKQELAH FKKTTLFQAL LMGRKTYESL PKVFEKRTIF 

        70         80         90        100        110        120 
LLSKDQNYRF EEKGSEVKVI NDFWPLIKSY QANKEKDLFI CGGKSVYEQT INECDQLIVS 

       130        140        150        160 
IIKKKYKGDQ FLKVDLSKFV LNEVVEFEEF NVNYYRKKQQ 

P47470 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

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