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[1]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 33530 / G-37 / NCTC 10195;
PubMed=7569993 [NCBI, ExPASy, EBI, Israel, Japan]
Fraser C.M.,
Gocayne J.D.,
White O.,
Adams M.D.,
Clayton R.A.,
Fleischmann R.D.,
Bult C.J.,
Kerlavage A.R.,
Sutton G.G.,
Kelley J.M.,
Fritchman J.L.,
Weidman J.F.,
Small K.V.,
Sandusky M.,
Fuhrmann J.L.,
Nguyen D.T.,
Utterback T.R.,
Saudek D.M.,
Phillips C.A., ![]()
Merrick J.M.,
Tomb J.-F.,
Dougherty B.A.,
Bott K.F.,
Hu P.-C.,
Lucier T.S.,
Peterson S.N.,
Smith H.O.,
Hutchison C.A. III,
Venter J.C.;
"The minimal gene complement of Mycoplasma genitalium.";
Science 270:397-403(1995).
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- FUNCTION: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
- CATALYTIC ACTIVITY: Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2.
- COFACTOR: Thiamine pyrophosphate (By similarity).
- SUBUNIT: Heterodimer of an alpha and a beta chain (By similarity).
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Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms.
Distributed under the Creative Commons Attribution-NoDerivs License.
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| Length: 326 AA [This is the length of the unprocessed precursor] |
Molecular weight: 36026 Da [This is the MW of the unprocessed precursor] |
CRC64: 7C5A0ECCD8A17DD7 [This is a checksum on the sequence] |
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10 20 30 40 50 60
MSKIQVNNIE ALNNAMDLAL ERDQNVVLYG QDAGFEGGVF RATKGLQQKY GSERVWDCPI
70 80 90 100 110 120
AENSMAGIGV GAAIGGLKPI VEIQFSGFSF PAMFQIFVHA ARIRNRSRGV YTAPLVVRMP
130 140 150 160 170 180
MGGGIKALEH HSETLEAIYA QIAGLKTVMP SNPYDTKGLF LAAIESPDPV IFFEPKKLYR
190 200 210 220 230 240
AFRQEIPSDY YTVPIGEANL ISEGSELTIV SYGPTMFDLI NLVYSGELKD KGIELIDLRT
250 260 270 280 290 300
ISPWDKQTVF NSVKKTGRLL VVTEAVKSFT TSAEIITSVT EELFTYLKKA PQRVTGFDIV
310 320
VPLARGEKYQ FEINARVIDA VNQLLK
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P47515 in FASTA format |
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