NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Cotyledon;
DOI=10.1023/A:1005742916292; PubMed=9037166 [NCBI, ExPASy, EBI, Israel, Japan]
Esaka M., Yamada N., Kitabayashi M., Setoguchi Y., Tsugeki R., Kondo M., Nishimura M.;
"cDNA cloning and differential gene expression of three catalases in pumpkin.";
Plant Mol. Biol. 33:141-155(1997).

Comments

FUNCTION: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
CATALYTIC ACTIVITY: 2 H₂O₂ = O₂ + 2 H₂O.
COFACTOR: Heme group (By similarity).
SUBUNIT: Homotetramer (By similarity).
SUBCELLULAR LOCATION: Peroxisome (By similarity).
TISSUE SPECIFICITY: Abundant in green cotyledons, etiolated cotyledons, green hypocotyl and root, but not in young leaf.
SIMILARITY: Belongs to the catalase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

D55647; BAA09508.1; -; mRNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

PIR

T09756; T09756.

3D structure databases

HSSP

P46206; 1M7S. [HSSP ENTRY / PDB]

ModBase

P48352.

Family and domain databases

InterPro

IPR002226; Catalase.
IPR011614; Catalase_N.
Graphical view of domain structure.

Gene3D

G3DSA:2.40.180.10; Catalase_N; 1.

PANTHER

PTHR11465; Catalase; 1.

Pfam

PF00199; Catalase; 1.
Pfam graphical view of domain structure.

PRINTS

PR00067; CATALASE.

ProDom

PD000510; Catalase; 1.
[Domain structure / List of seq. sharing at least 1 domain]

PROSITE

PS00437; CATALASE_1; 1.
PS00438; CATALASE_2; 1.

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Heme; Hydrogen peroxide; Iron; Metal-binding; Oxidoreductase; Peroxidase; Peroxisome.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 492`	`492`	`Catalase isozyme 3.`	`PRO_0000084937`
`ACT_SITE`	`65 65`		`By similarity.`
`ACT_SITE`	`138 138`		`By similarity.`
`METAL`	`347 347`		`Iron (heme axial ligand) (By similarity).`

Sequence information

Length: 492 AA [This is the length of the unprocessed precursor]

Molecular weight: 57137 Da [This is the MW of the unprocessed precursor]

CRC64: 8FDBEC7751660A6A [This is a checksum on the sequence]

        10         20         30         40         50         60 
MDPYKYRPSS AYNTPFCTTN SGAPIWNNTA VMSVGERGPI LLEDYQLIEK IATFTRERIP 

        70         80         90        100        110        120 
ERVVHRRGAS AKGFFEVTHD ISNLTCADFL RAPGVQTPVI VRFSTVIHER GSPETLRDPR 

       130        140        150        160        170        180 
GFAVKFYTRE GNFDLVGNNF PVFFVRDAMQ FPDVIRAFKP NPKSHLQEPW RYLDFCSYHP 

       190        200        210        220        230        240 
ESLLSFAWFY DDVGIPINYR HMEGFGVQAY SLINKSGKAR LVKFHWKPTC GVKSMMEEEA 

       250        260        270        280        290        300 
IRIGGTNHSH ATQDLYESIA AGNFPEWRLY IQTIDYEDQN KYDFEPLDTT ITWPEDVVPL 

       310        320        330        340        350        360 
QPVGRLVLNK NIDNFFAENE MLAFSMSLVP GIHYSDDKML QARSFAYADT QRHRLGPNYL 

       370        380        390        400        410        420 
QLPVNAPKCP HHNNHHEGFM NFMHRDEEVN YFPSRYDPCR HAEKFPMPPN VLTGKRERCV 

       430        440        450        460        470        480 
IPKENNNFKQ AGDRYRSWAP DRQDRFVKRF VEALSDPRVT DEVRNIWISY WSQADRSLGQ 

       490 
KIASRLNVRP NI

P48352 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools