ID   CATA1_NICPL             Reviewed;         485 AA.
AC   P49315;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 1.
DT   25-NOV-2008, entry version 51.
DE   RecName: Full=Catalase isozyme 1;
DE            EC=1.11.1.6;
DE   Flags: Fragment;
GN   Name=CAT1;
OS   Nicotiana plumbaginifolia (Leadwort-leaved tobacco).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons;
OC   asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC   Nicotiana.
OX   NCBI_TaxID=4092;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Leaf;
RX   MEDLINE=95010681; PubMed=7925949; DOI=10.1016/0014-5793(94)00923-6;
RA   Willekens H., Villarroel R., van Montagu M., Inze D., van Camp W.;
RT   "Molecular identification of catalases from Nicotiana plumbaginifolia
RT   (L.).";
RL   FEBS Lett. 352:79-83(1994).
CC   -!- FUNCTION: Occurs in almost all aerobically respiring organisms and
CC       serves to protect cells from the toxic effects of hydrogen
CC       peroxide.
CC   -!- CATALYTIC ACTIVITY: 2 H(2)O(2) = O(2) + 2 H(2)O.
CC   -!- COFACTOR: Heme group.
CC   -!- SUBUNIT: Homotetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Peroxisome (Potential).
CC   -!- INDUCTION: By paraquat and 3-aminotriazole.
CC   -!- SIMILARITY: Belongs to the catalase family.
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DR   EMBL; Z36975; CAA85424.1; -; mRNA.
DR   PIR; S48650; S48650.
DR   HSSP; P46206; 1M7S.
DR   GO; GO:0005777; C:peroxisome; IEA:UniProtKB-KW.
DR   GO; GO:0004096; F:catalase activity; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0042744; P:hydrogen peroxide catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   InterPro; IPR002226; Catalase.
DR   InterPro; IPR011614; Catalase_N.
DR   Gene3D; G3DSA:2.40.180.10; Catalase_N; 1.
DR   PANTHER; PTHR11465; Catalase; 1.
DR   Pfam; PF00199; Catalase; 1.
DR   PRINTS; PR00067; CATALASE.
DR   ProDom; PD000510; Catalase; 1.
DR   PROSITE; PS00437; CATALASE_1; 1.
DR   PROSITE; PS00438; CATALASE_2; 1.
DR   PROSITE; PS51402; CATALASE_3; 1.
PE   2: Evidence at transcript level;
KW   Heme; Hydrogen peroxide; Iron; Metal-binding; Oxidoreductase;
KW   Peroxidase; Peroxisome.
FT   CHAIN        <1    485       Catalase isozyme 1.
FT                                /FTId=PRO_0000084949.
FT   ACT_SITE     58     58       By similarity.
FT   ACT_SITE    131    131       By similarity.
FT   METAL       341    341       Iron (heme axial ligand) (By similarity).
FT   NON_TER       1      1
SQ   SEQUENCE   485 AA;  55850 MW;  00BA53BEF7699A13 CRC64;
     PSSAFNSPFC TTNSGAPVFN NNSSLTVGAR GPVLLEDYHL VEKLANFDRE RVPERVVHAR
     GASAKGFFEV THDITHLTCA DFLRAPGVQT PVIVRFSTVI HERGSPETLR DPRGFAVKFY
     TREGNFDLVG NNFPVFFIRD GMKFPDMVHA LKPNPKSHIQ ENWRVLDFFS HVPESLHMFT
     FLFDDIGIPQ DYRHMDGSGV HTFTLINKAG KSTYVKFHWK PTCGVKSLLE DEAARVGGAN
     HSHATQDLYD SIAAGNYPEW KLFIQTMDPD HEDRFDFDPL DVTKTWPEDI LPLQPVGRLV
     LNKNIDNFSN ENEQLAFCPS IVVPGVYYSD DKMLQTRIFS YSDTQRYRLG PNYLQLPANA
     PKCAHHNNHY DGSMNFMHRD EEIDYFPSRY DPVRHAEKYP IPSTMCTGKR EKCVIQKENN
     FKQPGERYRS FTPDRQERFI RRWVETLSDP RITYEIRSIW ISYWSQADKS LGQKLASRLN
     VRPSI
//