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UniProtKB/Swiss-Prot entry P54552


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name P5CR2_BACSU
Primary accession number P54552
Secondary accession numbers None
Integrated into Swiss-Prot on October 1, 1996
Sequence was last modified on October 1, 1996 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 60)
Name and origin of the protein
Protein name Pyrroline-5-carboxylate reductase 2
Synonyms P5C reductase 2
P5CR 2
EC 1.5.1.2
Gene name
Name: proI
Synonyms: yqjO
OrderedLocusNames: BSU23800
From
Bacillus subtilis [TaxID: 1423] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=168 / JH642;
PubMed=8969508 [NCBI, ExPASy, EBI, Israel, Japan]
Mizuno M., Masuda S., Takemaru K., Hosono S., Sato T., Takeuchi M., Kobayashi Y.;
"Systematic sequencing of the 283 kb 210 degrees-232 degrees region of the Bacillus subtilis genome containing the skin element and many sporulation genes.";
Microbiology 142:3103-3111(1996).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=168;
DOI=10.1038/36786; PubMed=9384377 [NCBI, ExPASy, EBI, Israel, Japan]
Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.;
"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.";
Nature 390:249-256(1997).
[3]
FUNCTION.
DOI=10.1128/JB.183.14.4389-4392.2001; PubMed=11418582 [NCBI, ExPASy, EBI, Israel, Japan]
Belitsky B.R., Brill J., Bremer E., Sonenshein A.L.;
"Multiple genes for the last step of proline biosynthesis in Bacillus subtilis.";
J. Bacteriol. 183:4389-4392(2001).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
D84432; BAA12621.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
Z99116; CAB14312.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR G69964; G69964.
RefSeq NP_390261.1; -.
3D structure databases
ModBase P54552.
Enzyme and pathway databases
BioCyc BSUB224308:BSU2379-MON; -.
Organism-specific databases
SubtiList BG11744; proI. [Micado]
Family and domain databases
InterPro IPR004455; NADP_OxRdtase_F420.
IPR000304; P5CR.
Graphical view of domain structure.
PANTHER PTHR11645; P5CR; 1.
Pfam PF03807; F420_oxidored; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000193; Pyrrol-5-carb_rd; 1.
TIGRFAMs TIGR00112; proC; 1.
PROSITE PS00521; P5CR; 1.
BLOCKS P54552.
Genome annotation databases
GeneID 938697; -.
GenomeReviews AL009126_GR; BSU23800.
KEGG bsu:BSU23800; -.
NMPDR fig|224308.1.peg.2385; -.
Phylogenomic databases
HOGENOM P54552; -.
Other
LinkHub P54552; -.
Genome annotation databases
CMR P54552; BSU23800.
Other
ProtoNet P54552.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Complete proteome; Cytoplasm; NADP; Oxidoreductase; Proline biosynthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   278  278     Pyrroline-5-carboxylate reductase 2. PRO_0000187286
Sequence information
Length: 278 AA [This is the length of the unprocessed precursor] Molecular weight: 30396 Da [This is the MW of the unprocessed precursor] CRC64: 4B69DB527E55345E [This is a checksum on the sequence]
        10         20         30         40         50         60 
MKKIGFVGAG SMAEAMINGI LQSGITKPEH IYITNRSNDE RLIELKETYS VRPCRDKNEF 

        70         80         90        100        110        120 
FTHTDIIILA FKPKDAAESI DSIRPYIKDQ LVISVLAGLT IETIQHYFGR KLAVIRVMPN 

       130        140        150        160        170        180 
TSAAIRKSAT GFSVSTEASK NDIIAAKALL ETIGDATLVE ERHLDAVTAI AGSGPAYVYR 

       190        200        210        220        230        240 
YIEAMEKAAQ KVGLDKETAK ALILQTMAGA TDMLLQSGKQ PEKLRKEITS PGGTTEAGLR 

       250        260        270 
ALQDSRFEEA IIHCIEETAK RSAEIKEQFA GAALERHS 

P54552 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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