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UniProtKB/Swiss-Prot entry P57154

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name METF_BUCAI
Primary accession number P57154
Secondary accession numbers None
Integrated into Swiss-Prot on December 1, 2000
Sequence was last modified on December 1, 2000 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 38)
Name and origin of the protein
Protein name 5,10-methylenetetrahydrofolate reductase
Synonym EC 1.5.1.20
Gene name
Name: metF
OrderedLocusNames: BU046
From
Buchnera aphidicola subsp. Acyrthosiphon pisum (Acyrthosiphon pisum symbiotic bacterium) [TaxID: 118099] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Buchnera.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Tokyo 1998;
DOI=10.1038/35024074; PubMed=10993077 [NCBI, ExPASy, EBI, Israel, Japan]
Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.;
"Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS.";
Nature 407:81-86(2000).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BA000003; BAB12769.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_239883.1; -.
3D structure databases
HSSP P00394; 1B5T. [HSSP ENTRY / PDB]
ModBase P57154.
Enzyme and pathway databases
BioCyc BSP107806:BU046-MON; -.
Family and domain databases
InterPro IPR003171; Mehydrof_redctse.
IPR004620; MTHF_reductase_bac.
Graphical view of domain structure.
Pfam PF02219; MTHFR; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00676; fadh2; 1.
BLOCKS P57154.
Genome annotation databases
GeneID 1109550; -.
GenomeReviews BA000003_GR; BU046.
KEGG buc:BU046; -.
Phylogenomic databases
HOGENOM P57154; -.
Genome annotation databases
CMR P57154; BU046.
Other
ProtoNet P57154.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Complete proteome; FAD; Flavoprotein; Methionine biosynthesis; NAD; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   292  292     5,10-methylenetetrahydrofolate reductase. PRO_0000190258
Sequence information
Length: 292 AA [This is the length of the unprocessed precursor] Molecular weight: 33730 Da [This is the MW of the unprocessed precursor] CRC64: 1D2A9E1B4D6E0DA9 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MKNYSQYHQD IMNQKLENIR NNIQCSFEFF PPKNSFLEEN LWSTVNRLSL LKPKFFSVTY 

        70         80         90        100        110        120 
GANTGEREKT YDTVQKIYKK TGIITAAHLT CIDSTPHKLK EIAYNYWNSG IKSIVALRGD 

       130        140        150        160        170        180 
TLEKDYRHTM YAVDLVLLLK KIADFDISVA AYPELHPESK NVKSDILNLK KKVDAGASRA 

       190        200        210        220        230        240 
ITQFFFNIES YLRFRDNCIK NKINIDIIPG ILPVCNFQKL KRFSSMTNVK IPKWMLDMFN 

       250        260        270        280        290 
GLDDDIFTQK IIGSSIAIDM VKKLSCEGVK NFHFYTLNQS DITYSICHIL GL
P57154 in FASTA format

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