ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry P58072

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name G3P3_ECO57
Primary accession number P58072
Secondary accession numbers None
Integrated into Swiss-Prot on May 4, 2001
Sequence was last modified on May 4, 2001 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 51)
Name and origin of the protein
Protein name Glyceraldehyde-3-phosphate dehydrogenase C
Synonyms GAPDH-C
EC 1.2.1.12
Gene name
Name: gapC
OrderedLocusNames: Z2304, ECs2022
From
Escherichia coli O157:H7 [TaxID: 83334] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
DOI=10.1038/35054089; PubMed=11206551 [NCBI, ExPASy, EBI, Israel, Japan]
Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J., Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A., Blattner F.R.;
"Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
Nature 409:529-533(2001).
[2]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
DOI=10.1093/dnares/8.1.11; PubMed=11258796 [NCBI, ExPASy, EBI, Israel, Japan]
Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K., Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S., Shiba T., Hattori M., Shinagawa H.;
"Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and genomic comparison with a laboratory strain K-12.";
DNA Res. 8:11-22(2001).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE005174; AAG56359.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BA000007; BAB35445.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR C85737; C85737.
F90881; F90881.
RefSeq NP_287745.1; -.
NP_310049.1; -.
3D structure databases
HSSP P17721; 1HDG. [HSSP ENTRY / PDB]
ModBase P58072.
Enzyme and pathway databases
BioCyc ECOL83334:ECS2022-MON; -.
Family and domain databases
InterPro IPR000173; GlycerAld_3-P_DHase.
IPR006424; Glyceraldehyde-3-P_DHase_1.
Graphical view of domain structure.
PANTHER PTHR10836; GAP_DH; 1.
Pfam PF02800; Gp_dh_C; 1.
PF00044; Gp_dh_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000149; GAP_DH; 1.
PRINTS PR00078; G3PDHDRGNASE.
TIGRFAMs TIGR01534; GAPDH-I; 1.
PROSITE PS00071; GAPDH; 1.
BLOCKS P58072.
Genome annotation databases
GeneID 917219; -.
960993; -.
GenomeReviews BA000007_GR; ECs2022.
AE005174_GR; Z2304.
KEGG ece:Z2304; -.
ecs:ECs2022; -.
Phylogenomic databases
HOGENOM P58072; -.
Other
LinkHub P58072; -.
Genome annotation databases
CMR P58072; Z2304.
Other
ProtoNet P58072.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; Glycolysis; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   333  333     Glyceraldehyde-3-phosphate dehydrogenase C. PRO_0000145652
NP_BIND   11    12  2     NAD (By similarity). 
REGION   149   151  3     Glyceraldehyde 3-phosphate binding (By similarity). 
REGION   209   210  2     Glyceraldehyde 3-phosphate binding (By similarity). 
ACT_SITE   150   150        Nucleophile (By similarity). 
BINDING   34    34        NAD (By similarity). 
BINDING   78    78        NAD; via carbonyl oxygen (By similarity). 
BINDING   180   180        Glyceraldehyde 3-phosphate (By similarity). 
BINDING   232   232        Glyceraldehyde 3-phosphate (By similarity). 
BINDING   315   315        NAD (By similarity). 
SITE   177   177  1     Activates thiol group during catalysis (By similarity). 
Sequence information
Length: 333 AA [This is the length of the unprocessed precursor] Molecular weight: 35763 Da [This is the MW of the unprocessed precursor] CRC64: A2F77CB2E773E64C [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MSKVGINGFG RIGRLVLRRL LEVKSNIDVV AINDLTSPKI LAYLLKHDSN YGPFPWSVDF 

        70         80         90        100        110        120 
TEDSLIVDGK SIAVYAEKEA KNIPWKAKGA EIIVECTGFY TSAEKSQAHL DAGAKKVLIS 

       130        140        150        160        170        180 
APAGEMKTIV YKVNDDTLDG NDTIVSVASC TTNCLAPMAK ALHDSFGIEV GTMTTIHAYT 

       190        200        210        220        230        240 
GTQSLVDGPR GKDLRASRAA AENIIPHTTG AAKAIGLVIP ELSGKLKGHA QRVPVKTGSV 

       250        260        270        280        290        300 
TELVSILGKK VTAEEVNNAL KQATTNNESF GYTDEEIVSS DIIGSHFGSV FDATQTEITA 

       310        320        330 
VGDLQLVKTV AWYDNEYGFV TQLIRTLEKF AKL
P58072 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA) 		Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Hosted by ca flag CBR Canada Mirror sites: Australia Brazil China Korea Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!