NUCLEOTIDE SEQUENCE [GENOMIC DNA].
DOI=10.1046/j.1365-2958.2003.03582.x; PubMed=12828649 [NCBI, ExPASy, EBI, Israel, Japan]
Youderian P.A., Burke N., White D.J., Hartzell P.L.;
"Identification of genes required for adventurous gliding motility in Myxococcus xanthus with the transposable element mariner.";
Mol. Microbiol. 49:555-570(2003).

Comments

CATALYTIC ACTIVITY: N²-acetyl-L-ornithine + 2-oxoglutarate = N-acetyl-L-glutamate 5-semialdehyde + L-glutamate.
COFACTOR: Pyridoxal phosphate (By similarity).
PATHWAY: Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 4/4 .
SUBCELLULAR LOCATION: Cytoplasm (Probable).
MISCELLANEOUS: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.
SIMILARITY: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AY204472; AAO22926.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

3D structure databases

HSSP

P12995; 1QJ3. [HSSP ENTRY / PDB]

ModBase

P59318.

Ontologies

GO:0005737;	Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0003992;	Molecular function: acetylornithine transaminase activity (inferred from electronic annotation from HAMAP).
GO:0030170;	Molecular function: pyridoxal phosphate binding (inferred from electronic annotation from InterPro).
GO:0006526;	Biological process: arginine biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_01107; -; 1.
PBIL [Tree]

InterPro

IPR005814; Aminotrans_3.
IPR004636; ArgD_aminotrans.
IPR015421; PyrdxlP-dep_Trfase_major_sub1.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.640.10; PyrdxlP-dep_Trfase_major_sub1; 1.

PANTHER

PTHR11986; Aminotrans_3; 1.
PTHR11986:SF19; ArgD_aminotrans; 1.

Pfam

PF00202; Aminotran_3; 1.
Pfam graphical view of domain structure.

TIGRFAMs

TIGR00707; argD; 1.

PROSITE

PS00600; AA_TRANSFER_CLASS_3; 1.

ProtoNet

P59318.

Other

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Amino-acid biosynthesis; Aminotransferase; Arginine biosynthesis; Cytoplasm; Pyridoxal phosphate; Transferase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 401`	`401`	`Acetylornithine aminotransferase.`	`PRO_0000112758`
`BINDING`	`268 268`		`Pyridoxal phosphate (covalent) (By similarity).`

Sequence information

Length: 401 AA [This is the length of the unprocessed precursor]

Molecular weight: 42652 Da [This is the MW of the unprocessed precursor]

CRC64: 423403389D7947E5 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MTALSQSEPS LSASSDSSTD ALVQKAKRHL LQNYKQPPFV LARGQGARVW DMDGREYLDL 

        70         80         90        100        110        120 
IGGIATCALG HCHPEVVAAA KAQLDSLWHV SNVFYSQPQI DLAAQLTEWS GLSRAFFCNS 

       130        140        150        160        170        180 
GAEANEALLK LTRKVMKDRG TPERFEVISF DSSFHGRTLA TVTATGQAKY QKGFEPLPAG 

       190        200        210        220        230        240 
FTHVPYGDLE AVRKAVGPAT AAILVEPIQG EGGVRMAPLG FLVGLRALCD EHGLLLLVDE 

       250        260        270        280        290        300 
VQTGMGRTGK PFGFMHEGIV PDGISVAKAL GNGLPIGAML CKEELGASLT PGTHGSTFGG 

       310        320        330        340        350        360 
NPVAAAAANA VVRILRRPGF LDEVQEKGAY LLARARELQG RLPAGRIQAV RGQGLLVGVQ 

       370        380        390        400 
LDHKVAPVIA QVHEEGLLVN PAGDRTMLFA PPFIVTVREL D

P59318 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools