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UniProtKB/Swiss-Prot entry P60535


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name HIS2_CORDI
Primary accession number P60535
Secondary accession numbers None
Integrated into Swiss-Prot on March 15, 2004
Sequence was last modified on March 15, 2004 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 33)
Name and origin of the protein
Protein name Phosphoribosyl-ATP pyrophosphatase
Synonyms PRA-PH
EC 3.6.1.31
Gene name
Name: hisE
OrderedLocusNames: DIP1257
From
Corynebacterium diphtheriae [TaxID: 1717] [HAMAP proteome]
Taxonomy Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; Corynebacterineae; Corynebacteriaceae; Corynebacterium.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 700971 / NCTC 13129 / Biotype gravis;
DOI=10.1093/nar/gkg874; PubMed=14602910 [NCBI, ExPASy, EBI, Israel, Japan]
Cerdeno-Tarraga A.-M., Efstratiou A., Dover L.G., Holden M.T.G., Pallen M.J., Bentley S.D., Besra G.S., Churcher C.M., James K.D., De Zoysa A., Chillingworth T., Cronin A., Dowd L., Feltwell T., Hamlin N., Holroyd S., Jagels K., Moule S., Quail M.A., Rabbinowitsch E., Rutherford K.M., Thomson N.R., Unwin L., Whitehead S., Barrell B.G., Parkhill J.;
"The complete genome sequence and analysis of Corynebacterium diphtheriae NCTC13129.";
Nucleic Acids Res. 31:6516-6523(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BX248357; CAE49786.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_939612.1; -.
3D structure databases
ModBase P60535.
Enzyme and pathway databases
BioCyc CDIP257309:DIP1257-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0004636; Molecular function: phosphoribosyl-ATP diphosphatase activity (inferred from electronic annotation from HAMAP).
GO:0000105; Biological process: histidine biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01020; -; 1.
PBIL [Tree]
InterPro IPR008179; PRib-ATP_pyrophosphohydrolase.
Graphical view of domain structure.
Pfam PF01503; PRA-PH; 1.
Pfam graphical view of domain structure.
ProDom PD002611; Pra_PH/CH; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR03188; histidine_hisI; 1.
ProtoNet P60535.
Genome annotation databases
GeneID 2650087; -.
GenomeReviews BX248353_GR; DIP1257.
KEGG cdi:DIP1257; -.
NMPDR fig|257309.1.peg.1203; -.
Phylogenomic databases
HOGENOM P60535; -.
Other
LinkHub P60535; -.
Genome annotation databases
CMR P60535; DIP1257.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Complete proteome; Cytoplasm; Histidine biosynthesis; Hydrolase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   87  87     Phosphoribosyl-ATP pyrophosphatase. PRO_0000136359
Sequence information
Length: 87 AA [This is the length of the unprocessed precursor] Molecular weight: 9876 Da [This is the MW of the unprocessed precursor] CRC64: 77EBD517AAF226FE [This is a checksum on the sequence]
        10         20         30         40         50         60 
MKNFDSLYHE LAERAEKRPE GSGTVAALNS SLHTLGKKVI EEAGEVWLAA EYQSDAELAE 

        70         80 
EISQLMYWAQ VIMIKRGLTP EDIYKYL 

P60535 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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