[1]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA].
DOI=10.1016/S0006-291X(83)80040-0; PubMed=6312994 [NCBI, ExPASy, EBI, Israel, Japan]
Maeda S.,
Nishino N.,
Obaru K.,
Mita S.,
Nomiyama H.,
Shimada K.,
Fujimoto K.,
Teranishi T.,
Hirano T.,
Onoue K.;
"Cloning of interleukin 2 mRNAs from human tonsils.";
Biochem. Biophys. Res. Commun. 115:1040-1047(1983).
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[2]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
DOI=10.1038/302305a0; PubMed=6403867 [NCBI, ExPASy, EBI, Israel, Japan]
Taniguchi T.,
Matsui H.,
Fujita T.,
Takaoka C.,
Kashima N.,
Yoshimoto R.,
Hamuro J.;
"Structure and expression of a cloned cDNA for human interleukin-2.";
Nature 302:305-310(1983).
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[3]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA].
DOI=10.1093/nar/11.13.4307; PubMed=6306584 [NCBI, ExPASy, EBI, Israel, Japan]
Devos R.,
Plaetinck G.,
Cheroutre H.,
Simons G.,
Degrave W.,
Tavernier J.,
Remaut E.,
Fiers W.;
"Molecular cloning of human interleukin 2 cDNA and its expression in E. coli.";
Nucleic Acids Res. 11:4307-4323(1983).
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[4]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA].
PubMed=6324170 [NCBI, ExPASy, EBI, Israel, Japan]
Fujita T.,
Takaoka C.,
Matsui H.,
Taniguchi T.;
"Structure of the human interleukin 2 gene.";
Proc. Natl. Acad. Sci. U.S.A. 80:7437-7441(1983).
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[5]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA].
DOI=10.1093/nar/12.12.5005; PubMed=6330695 [NCBI, ExPASy, EBI, Israel, Japan]
Holbrook N.J.,
Lieber M.,
Crabtree G.R.;
"DNA sequence of the 5' flanking region of the human interleukin 2 gene: homologies with adult T-cell leukemia virus.";
Nucleic Acids Res. 12:5005-5013(1984).
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[6]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA].
PubMed=6608729 [NCBI, ExPASy, EBI, Israel, Japan]
Holbrook N.J.,
Smith K.A.,
Fornace A.J. Jr.,
Comeau C.M.,
Wiskocil R.L.,
Crabtree G.R.;
"T-cell growth factor: complete nucleotide sequence and organization of the gene in normal and malignant cells.";
Proc. Natl. Acad. Sci. U.S.A. 81:1634-1638(1984).
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[7]
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NUCLEOTIDE SEQUENCE [MRNA].
PubMed=7722480 [NCBI, ExPASy, EBI, Israel, Japan]
Eizenberg O.,
Faber-Elman A.,
Lotan M.,
Schwartz M.;
"Interleukin-2 transcripts in human and rodent brains: possible expression by astrocytes.";
J. Neurochem. 64:1928-1936(1995).
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[8]
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NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Placenta;
DOI=10.1002/(SICI)1098-2795(199602)43:2<180::AID-MRD7>3.3.CO;2-D; PubMed=8824916 [NCBI, ExPASy, EBI, Israel, Japan]
Chernicky C.L.,
Tan H.,
Burfeind P.,
Ilan J.,
Ilan J.;
"Sequence of interleukin-2 isolated from human placental poly A+ RNA: possible role in maintenance of fetal allograft.";
Mol. Reprod. Dev. 43:180-186(1996).
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[9]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA].
SeattleSNPs program for genomic applications;
Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases.
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[10]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Blood;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
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[11]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-68.
Nishino N.,
Obaru K.,
Maeda S.,
Shimada K.,
Onoue K.;
"Organization of the DNA regions flanking the human interleukin 2 gene.";
Biomed. Res. 6:197-205(1985).
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[12]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-69.
PubMed=3491296 [NCBI, ExPASy, EBI, Israel, Japan]
Siebenlist U.,
Durand D.B.,
Bressler P.,
Holbrook N.J.,
Norris C.A.,
Kamoun M.,
Kant J.A.,
Crabtree G.R.;
"Promoter region of interleukin-2 gene undergoes chromatin structure changes and confers inducibility on chloramphenicol acetyltransferase gene during activation of T cells.";
Mol. Cell. Biol. 6:3042-3049(1986).
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[13]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 21-153.
DOI=10.1021/bi00418a034; PubMed=3264184 [NCBI, ExPASy, EBI, Israel, Japan]
Weir M.P.,
Chaplin M.A.,
Wallace D.M.,
Dykes C.W.,
Hobden A.N.;
"Structure-activity relationships of recombinant human interleukin 2.";
Biochemistry 27:6883-6892(1988).
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[14]
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PROTEIN SEQUENCE OF 21-153, DISULFIDE BOND, AND GLYCOSYLATION AT THR-23.
PubMed=6333684 [NCBI, ExPASy, EBI, Israel, Japan]
Robb R.J.,
Kutny R.M.,
Panico M.,
Morris H.R.,
Chowdhry V.;
"Amino acid sequence and post-translational modification of human interleukin 2.";
Proc. Natl. Acad. Sci. U.S.A. 81:6486-6490(1984).
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[15]
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GLYCOSYLATION AT THR-23.
PubMed=2793860 [NCBI, ExPASy, EBI, Israel, Japan]
Conradt H.S.,
Nimtz M.,
Dittmar K.E.J.,
Lindenmaier W.,
Hoppe J.,
Hauser H.;
"Expression of human interleukin-2 in recombinant baby hamster kidney, Ltk-, and Chinese hamster ovary cells. Structure of O-linked carbohydrate chains and their location within the polypeptide.";
J. Biol. Chem. 264:17368-17373(1989).
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[16]
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X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS).
PubMed=3500515 [NCBI, ExPASy, EBI, Israel, Japan]
Brandhuber B.J.,
Boone T.,
Kenney W.C.,
McKay D.B.;
"Three-dimensional structure of interleukin-2.";
Science 238:1707-1709(1987).
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[17]
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COMPARISON OF X-RAY STRUCTURES.
PubMed=1631562 [NCBI, ExPASy, EBI, Israel, Japan]
Bazan J.F.;
"Unraveling the structure of IL-2.";
Science 257:410-412(1992).
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[18]
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RESPONSE TO ABOVE LETTER.
McKay D.B.;
Science 257:412-413(1992).
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[19]
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STRUCTURE BY NMR.
DOI=10.1021/bi00148a040; PubMed=1510960 [NCBI, ExPASy, EBI, Israel, Japan]
Mott H.R.,
Driscoll P.C.,
Boyd J.,
Cooke R.M.,
Weir M.P.,
Campbell I.D.;
"Secondary structure of human interleukin 2 from 3D heteronuclear NMR experiments.";
Biochemistry 31:7741-7744(1992).
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[20]
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3D-STRUCTURE MODELING.
DOI=10.1016/S0969-2126(94)00085-9; PubMed=7529123 [NCBI, ExPASy, EBI, Israel, Japan]
Bamborough P.,
Hedgecock C.J.,
Richards W.G.;
"The interleukin-2 and interleukin-4 receptors studied by molecular modelling.";
Structure 2:839-851(1994).
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[21]
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X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) OF 21-153 IN COMPLEX WITH IL2RA; IL2RB AND IL2RC.
DOI=10.1126/science.1117893; PubMed=16293754 [NCBI, ExPASy, EBI, Israel, Japan]
Wang X.,
Rickert M.,
Garcia K.C.;
"Structure of the quaternary complex of interleukin-2 with its alpha, beta, and gammac receptors.";
Science 310:1159-1163(2005).
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[22]
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X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF 21-153 IN COMPLEX WITH IL2RA; IL2RB AND IL2RC, AND DISULFIDE BOND.
DOI=10.1073/pnas.0511161103; PubMed=16477002 [NCBI, ExPASy, EBI, Israel, Japan]
Stauber D.J.,
Debler E.W.,
Horton P.A.,
Smith K.A.,
Wilson I.A.;
"Crystal structure of the IL-2 signaling complex: paradigm for a heterotrimeric cytokine receptor.";
Proc. Natl. Acad. Sci. U.S.A. 103:2788-2793(2006).
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