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UniProtKB/Swiss-Prot entry P66776


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name BUTA_STAAW
Primary accession number P66776
Secondary accession number Q99X89
Integrated into Swiss-Prot on October 11, 2004
Sequence was last modified on October 11, 2004 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 24)
Name and origin of the protein
Protein name Acetoin(diacetyl) reductase
Synonyms AR
EC 1.1.1.5
Acetoin dehydrogenase
Meso-2,3-butanediol dehydrogenase
Gene name
Name: butA
OrderedLocusNames: MW0100
From
Staphylococcus aureus (strain MW2) [TaxID: 196620] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Staphylococcus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1016/S0140-6736(02)08713-5; PubMed=12044378 [NCBI, ExPASy, EBI, Israel, Japan]
Baba T., Takeuchi F., Kuroda M., Yuzawa H., Aoki K., Oguchi A., Nagai Y., Iwama N., Asano K., Naimi T., Kuroda H., Cui L., Yamamoto K., Hiramatsu K.;
"Genome and virulence determinants of high virulence community-acquired MRSA.";
Lancet 359:1819-1827(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BA000033; BAB93965.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_644915.1; -.
3D structure databases
HSSP Q48436; 1GEG. [HSSP ENTRY / PDB]
ModBase P66776.
Enzyme and pathway databases
BioCyc SAUR196620:MW0100-MON; -.
Family and domain databases
InterPro IPR014007; 23BDH.
IPR002198; DHase_sc/Rdtase_SDR.
IPR002347; Glc/ribitol_DHase.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR19410; ADH_short_C2; 1.
Pfam PF00106; adh_short; 1.
Pfam graphical view of domain structure.
PRINTS PR00081; GDHRDH.
PR00080; SDRFAMILY.
TIGRFAMs TIGR02415; 23BDH; 1.
PROSITE PS00061; ADH_SHORT; 1.
BLOCKS P66776.
Genome annotation databases
GeneID 1004853; -.
GenomeReviews BA000033_GR; MW0100.
KEGG sam:MW0100; -.
Phylogenomic databases
HOGENOM P66776; -.
Genome annotation databases
CMR P66776; MW0100.
Other
ProtoNet P66776.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   258  258     Acetoin(diacetyl) reductase. PRO_0000054544
NP_BIND   8    32  25     NAD (By similarity). 
ACT_SITE   154   154        Proton acceptor (By similarity). 
ACT_SITE   158   158        By similarity. 
BINDING   141   141        Substrate (By similarity). 
Sequence information
Length: 258 AA [This is the length of the unprocessed precursor] Molecular weight: 27216 Da [This is the MW of the unprocessed precursor] CRC64: 114AFD0DC5D780CF [This is a checksum on the sequence]
        10         20         30         40         50         60 
MTNNKVALVT GGAQGIGFKI AERLVEDGFK VAVVDFNEEG AKAAALKLSS DGTKAIAIKA 

        70         80         90        100        110        120 
DVSNRDDVFN AVRQTAAQFG DFHVMVNNAG LGPTTPIDTI TEEQFKTVYG VNVAGVLWGI 

       130        140        150        160        170        180 
QAAHEQFKKF NHGGKIINAT SQAGVEGNPG LSLYCSTKFA VRGLTQVAAQ DLASEGITVN 

       190        200        210        220        230        240 
AFAPGIVQTP MMESIAVATA EEAGKPEAWG WEQFTSQIAL GRVSQPEDVS NVVSFLAGKD 

       250 
SDYITGQTII VDGGMRFR 

P66776 in FASTA format

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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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