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UniProtKB/Swiss-Prot entry P69740


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name MBHS_ECOL6
Primary accession number P69740
Secondary accession number P19928
Integrated into Swiss-Prot on April 26, 2005
Sequence was last modified on April 26, 2005 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 29)
Name and origin of the protein
Protein name Hydrogenase-1 small chain [Precursor]
Synonyms HYD1
EC 1.12.99.6
Membrane-bound hydrogenase 1 small subunit
NiFe hydrogenase
Gene name
Name: hyaA
OrderedLocusNames: c1113
From
Escherichia coli O6 [TaxID: 217992] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=O6:H1 / CFT073 / ATCC 700928 / UPEC;
DOI=10.1073/pnas.252529799; PubMed=12471157 [NCBI, ExPASy, EBI, Israel, Japan]
Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D., Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F., Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T., Donnenberg M.S., Blattner F.R.;
"Extensive mosaic structure revealed by the complete genome sequence of uropathogenic Escherichia coli.";
Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE014075; AAN79581.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_753038.1; -.
3D structure databases
HSSP P18187; 1FRF. [HSSP ENTRY / PDB]
ModBase P69740.
Family and domain databases
InterPro IPR001821; NiFe_hyd_ssu.
IPR013634; NiFe_hyd_ssu_N.
IPR006137; OxRdtase_q6.
IPR006311; Tat.
Graphical view of domain structure.
Pfam PF08425; NiFe_dehyd_N; 1.
PF01058; Oxidored_q6; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000310; NiFe_hyd_ssu; 1.
PRINTS PR00614; NIHGNASESMLL.
TIGRFAMs TIGR00391; hydA; 1.
TIGR01409; TAT_signal_seq; 1.
PROSITE PS51318; TAT; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS P69740.
Genome annotation databases
GeneID 1040006; -.
GenomeReviews AE014075_GR; c1113.
KEGG ecc:c1113; -.
Phylogenomic databases
HOGENOM P69740; -.
Genome annotation databases
CMR P69740; c1113.
Other
ProtoNet P69740.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
3Fe-4S; 4Fe-4S; Cell inner membrane; Cell membrane; Complete proteome; Iron; Iron-sulfur; Membrane; Metal-binding; Oxidoreductase; Periplasm; Signal; Transmembrane.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
SIGNAL   1    45  45     Tat-type signal (Potential). 
CHAIN   46   372  327     Hydrogenase-1 small chain. PRO_0000013428
TOPO_DOM   46   326  281     Periplasmic (Potential). 
TRANSMEM   327   347  21     Potential. 
TOPO_DOM   348   372  25     Cytoplasmic (Potential). 
METAL   62    62        Iron-sulfur 1 (4Fe-4S) (By similarity). 
METAL   65    65        Iron-sulfur 1 (4Fe-4S) (By similarity). 
METAL   160   160        Iron-sulfur 1 (4Fe-4S) (By similarity). 
METAL   194   194        Iron-sulfur 1 (4Fe-4S) (By similarity). 
METAL   232   232        Iron-sulfur 2 (4Fe-4S); via pros nitrogen (By similarity). 
METAL   235   235        Iron-sulfur 2 (4Fe-4S) (By similarity). 
METAL   260   260        Iron-sulfur 2 (4Fe-4S) (By similarity). 
METAL   266   266        Iron-sulfur 2 (4Fe-4S) (By similarity). 
METAL   275   275        Iron-sulfur 3 (3Fe-4S) (By similarity). 
METAL   294   294        Iron-sulfur 3 (3Fe-4S) (By similarity). 
METAL   297   297        Iron-sulfur 3 (3Fe-4S) (By similarity). 
Sequence information
Length: 372 AA [This is the length of the unprocessed precursor] Molecular weight: 40681 Da [This is the MW of the unprocessed precursor] CRC64: 4AD3ECB4220D2826 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MNNEETFYQA MRRQGVTRRS FLKYCSLAAT SLGLGAGMAP KIAWALENKP RIPVVWIHGL 

        70         80         90        100        110        120 
ECTCCTESFI RSAHPLAKDV ILSLISLDYD DTLMAAAGTQ AEEVFEDIIT QYNGKYILAV 

       130        140        150        160        170        180 
EGNPPLGEQG MFCISSGRPF IEKLKRAAAG ASAIIAWGTC ASWGCVQAAR PNPTQATPID 

       190        200        210        220        230        240 
KVITDKPIIK VPGCPPIPDV MSAIITYMVT FDRLPDVDRM GRPLMFYGQR IHDKCYRRAH 

       250        260        270        280        290        300 
FDAGEFVQSW DDDAARKGYC LYKMGCKGPT TYNACSSTRW NDGVSFPIQS GHGCLGCAEN 

       310        320        330        340        350        360 
GFWDRGSFYS RVVDIPQMGT HSTADTVGLT ALGVVAAAVG VHAVASAVDQ RRRHNQQPTE 

       370 
TEHQPGNEDK QA 

P69740 in FASTA format

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