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UniProtKB/Swiss-Prot entry P79273


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ACADS_PIG
Primary accession number P79273
Secondary accession numbers None
Integrated into Swiss-Prot on April 27, 2001
Sequence was last modified on May 1, 1997 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 67)
Name and origin of the protein
Protein name Short-chain specific acyl-CoA dehydrogenase, mitochondrial [Precursor]
Synonyms SCAD
EC 1.3.99.2
Butyryl-CoA dehydrogenase
Gene name
Name: ACADS
From
Sus scrofa (Pig) [TaxID: 9823] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae; Sus.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Liver;
Suzuki H., Itoh T., Kimura M., Murakami Y., Hamasima N., Yasue H.;
"Isolation of the pig short-chain acyl-CoA dehydrogenase gene and assignment to chromosome 14q16.2-q23.2.";
Submitted (NOV-1996) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
D89477; BAA13964.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_999063.1; -.
UniGene Ssc.14531
3D structure databases
HSSP P15651; 1JQI. [HSSP ENTRY / PDB]
SMR P79273; 28-412.
ModBase P79273.
Ontologies
GO
GO:0005759; Cellular component: mitochondrial matrix (inferred from electronic annotation from UniProtKB-SubCell).
QuickGo view.
Family and domain databases
InterPro IPR006091; Acyl-CoA_DHase/Oxase_M.
IPR006089; Acyl-CoA_DHase_CS.
IPR006092; Acyl-CoA_DHase_N.
IPR006090; Acyl-CoA_Oxase/DHase_1.
IPR013786; AcylCoA_DH/ox_N.
IPR013764; AcylCoA_oxidase/DH_1/2_C.
Graphical view of domain structure.
Gene3D G3DSA:2.40.110.10; Acyl_CoA_DH/ox_M; 1.
G3DSA:1.10.540.10; AcylCoA_DH/ox_N; 1.
G3DSA:1.20.140.10; AcylCoA_DH_1/2_C; 1.
Pfam PF00441; Acyl-CoA_dh_1; 1.
PF02770; Acyl-CoA_dh_M; 1.
PF02771; Acyl-CoA_dh_N; 1.
Pfam graphical view of domain structure.
PROSITE PS00072; ACYL_COA_DH_1; 1.
PS00073; ACYL_COA_DH_2; 1.
BLOCKS P79273.
Genome annotation databases
GeneID 396932; -.
KEGG ssc:396932; -.
Phylogenomic databases
HOVERGEN P79273; -.
Other
ProtoNet P79273.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
FAD; Fatty acid metabolism; Flavoprotein; Lipid metabolism; Mitochondrion; Oxidoreductase; Transit peptide.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
TRANSIT   1    24  24     Mitochondrion (By similarity). 
CHAIN   25   413  389     Short-chain specific acyl-CoA dehydrogenase, mitochondrial. PRO_0000000500
NP_BIND   152   161  10     FAD (By similarity). 
NP_BIND   185   187  3     FAD (By similarity). 
NP_BIND   366   370  5     FAD (By similarity). 
NP_BIND   395   397  3     FAD (By similarity). 
ACT_SITE   393   393        Proton acceptor (By similarity). 
BINDING   297   297        FAD (By similarity). 
Sequence information
Length: 413 AA [This is the length of the unprocessed precursor] Molecular weight: 44851 Da [This is the MW of the unprocessed precursor] CRC64: B8C480ADEFDF7E98 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MAAALLARAC GPVRGALWPR DCRRLHTIFQ SVELPETYQM LRQTCRDFAE KELVPIAAQV 

        70         80         90        100        110        120 
DKEHRFPEAQ VKKMGELGLM AMDVPEELSG AGLDYLAYTI AMEEISRGCA STGVIMSVNN 

       130        140        150        160        170        180 
FLYLGPILKF GSKEQKQQWI TPFTSGDKVG CFALSEPGNG SDAGAAATTA QADHDSWVLS 

       190        200        210        220        230        240 
GTKAWITNAW EASAAVVFAS TDRSLQNKGI SAFLVPMPTA GLTLGKKEDK LGIRASSTAN 

       250        260        270        280        290        300 
LIFEDCRIPK ENLLGEPGMG FKIAMKTLDM GRIGIASKAL GISQAALDCA VNYAENRRAF 

       310        320        330        340        350        360 
GVPLTKLQGI QFKLADMALA LESARLLTWR AAMLKDNKKN PFIKEPAMAK LAASEAATAI 

       370        380        390        400        410 
THQAIQILGG MGYVTEMPAE RHYRDARITE IYEGTSEIQR LVIAGHLLKS YRS 

P79273 in FASTA format

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