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UniProtKB/Swiss-Prot entry P80053


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name DHE2_SULSO
Primary accession number P80053
Secondary accession numbers None
Integrated into Swiss-Prot on March 1, 1992
Sequence was last modified on March 18, 2008 (Sequence version 3)
Annotations were last modified on    September 2, 2008 (Entry version 60)
Name and origin of the protein
Protein name Glutamate dehydrogenase 2
Synonyms GDH-2
EC 1.4.1.3
Gene name
Name: gdhA-2
Synonyms: gdhA
OrderedLocusNames: SSO1907
From
Sulfolobus solfataricus [TaxID: 2287] [HAMAP proteome]
Taxonomy Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Sulfolobus.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 35092 / DSM 1617 / JCM 11322 / P2;
DOI=10.1073/pnas.141222098; PubMed=11427726 [NCBI, ExPASy, EBI, Israel, Japan]
She Q., Singh R.K., Confalonieri F., Zivanovic Y., Allard G., Awayez M.J., Chan-Weiher C.C.-Y., Clausen I.G., Curtis B.A., De Moors A., Erauso G., Fletcher C., Gordon P.M.K., Heikamp-de Jong I., Jeffries A.C., Kozera C.J., Medina N., Peng X., Thi-Ngoc H.P., Redder P., Schenk M.E., Theriault C., Tolstrup N., Charlebois R.L., Doolittle W.F., Duguet M., Gaasterland T., Garrett R.A., Ragan M.A., Sensen C.W., Van der Oost J.;
"The complete genome of the crenarchaeon Sulfolobus solfataricus P2.";
Proc. Natl. Acad. Sci. U.S.A. 98:7835-7840(2001).
[2]
PROTEIN SEQUENCE OF 2-420.
STRAIN=DSM 5833 / MT-4;
PubMed=1730244 [NCBI, ExPASy, EBI, Israel, Japan]
Maras B., Consalvi V., Chiaraluce R., Politi L., de Rosa M., Bossa F., Scandurra R., Barra D.;
"The protein sequence of glutamate dehydrogenase from Sulfolobus solfataricus, a thermoacidophilic archaebacterium. Is the presence of N-epsilon-methyllysine related to thermostability?";
Eur. J. Biochem. 203:81-87(1992).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE006799; AAK42099.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR D90355; D90355.
S20286; S20286.
RefSeq NP_343309.1; -.
3D structure databases
HSSP P96110; 1B26. [HSSP ENTRY / PDB]
ModBase P80053.
Enzyme and pathway databases
BioCyc SSOL273057:SSO1907-MON; -.
Family and domain databases
InterPro IPR006095; Glu/Leu/Phe/Val_DHase.
IPR006096; Glu/Leu/Phe/Val_DHase_C.
IPR006097; Glu/Leu/Phe/Val_DHase_dimer.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR11606:SF2; GLFV_DH; 1.
Pfam PF00208; ELFV_dehydrog; 1.
PF02812; ELFV_dehydrog_N; 1.
Pfam graphical view of domain structure.
PRINTS PR00082; GLFDHDRGNASE.
PROSITE PS00074; GLFV_DEHYDROGENASE; 1.
BLOCKS P80053.
Genome annotation databases
GeneID 1453426; -.
GenomeReviews AE006641_GR; SSO1907.
KEGG sso:SSO1907; -.
NMPDR fig|273057.1.peg.1732; -.
Phylogenomic databases
HOGENOM P80053; -.
Genome annotation databases
CMR P80053; SSO1907.
Other
ProtoNet P80053.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Acetylation; Complete proteome; Direct protein sequencing; Methylation; NAD; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
INIT_MET   1     1        Removed. 
CHAIN   2   420  419     Glutamate dehydrogenase 2. PRO_0000182761
ACT_SITE   109   109        By similarity. 
MOD_RES   2     2        N-acetylmethionine. 
MOD_RES   254   254        N6-methyllysine. 
MOD_RES   260   260        N6-methyllysine. 
MOD_RES   372   372        N6-methyllysine. 
MOD_RES   391   391        N6-methyllysine. 
MOD_RES   392   392        N6-methyllysine. 
CONFLICT   203   203        E -> EE (in Ref. 2; AA sequence). 
CONFLICT   392   392        K -> KK (in Ref. 2; AA sequence). 
Sequence information
Length: 420 AA [This is the length of the unprocessed precursor] Molecular weight: 46031 Da [This is the MW of the unprocessed precursor] CRC64: D9283C66D305EED5 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MMEEVLSSSL YTQQVKKLYK VGELLGLDNE TLETLSQPER IIQVKIQIRG SDGKLKTFMG 

        70         80         90        100        110        120 
WRSQHNSALG PYKGGVRYHP NVTQDEVEAL SMIMTWKNSL LLLPYGGGKG GVRVDPKKLT 

       130        140        150        160        170        180 
REELEQLSRK YIQAIYKYLG SELDIPAPDV NTDSQTMAWF LDEYIKITGK VDFAVFTGKP 

       190        200        210        220        230        240 
VELGGIGVRL YSTGLGVATI AKEAANKFIG GVEEARVIIQ GFGNVGYYAG KFLSEMGAKI 

       250        260        270        280        290        300 
VGVSDSKGGV INEKGIDVGK AIEIKEKTGS VINYPEGRKV TNEELLISDC DILIPAALEN 

       310        320        330        340        350        360 
VINKFNAPKV KAKLIVEGAN GPLTADADEI MRQRGIAVVP DILANAGGVV GSYVEWANNK 

       370        380        390        400        410        420 
MGEIISDEEA KKLIVDRMNN AFNTLYDYHQ KKLEDHDLRT AAMALAVDRV VRAMKARGIL 

P80053 in FASTA format

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