[1]	PROTEIN SEQUENCE. PubMed=9612556 [NCBI, ExPASy, EBI, Israel, Japan] Kozlov E.A., Levitina T.L., Bobrovskaia M.T., Gudkova L.V., Latyshko N.V., Radomskii N.F.; "Complete amino acid sequence of catalase from the fungus Penicillium vitale."; Bioorg. Khim. 24:163-170(1998).

Comments

FUNCTION: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
CATALYTIC ACTIVITY: 2 H₂O₂ = O₂ + 2 H₂O.
COFACTOR: Heme group.
SIMILARITY: Belongs to the catalase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

3D structure databases
HSSP	P04040; 1QQW. [HSSP ENTRY / PDB]
ModBase	P81138.
Protein family/group databases
PeroxiBase	5322; PjaKat01.
Family and domain databases
InterPro	IPR002226; Catalase. IPR011614; Catalase_N. Graphical view of domain structure.
Gene3D	G3DSA:2.40.180.10; Catalase_N; 1.
PANTHER	PTHR11465; Catalase; 1.
Pfam	PF00199; Catalase; 1. Pfam graphical view of domain structure.
PRINTS	PR00067; CATALASE.
ProDom	PD000510; Catalase; 1. [Domain structure / List of seq. sharing at least 1 domain]
PROSITE	PS00437; CATALASE_1; 1. PS00438; CATALASE_2; 1. PS51402; CATALASE_3; 1. PROSITE graphical view of domain structure (profiles).
BLOCKS	P81138.
Other
ProtoNet	P81138.
UniRef	View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Direct protein sequencing; Heme; Hydrogen peroxide; Iron; Metal-binding; Oxidoreductase; Peroxidase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 696`	`696`	`Catalase.`	`PRO_0000084925`
`ACT_SITE`	`64 64`		`By similarity.`
`ACT_SITE`	`137 137`		`By similarity.`
`METAL`	`353 353`		`Iron (heme axial ligand) (By similarity).`

Sequence information

Length: 696 AA [This is the length of the unprocessed precursor]

Molecular weight: 77404 Da [This is the MW of the unprocessed precursor]

CRC64: 1A663CD3162C21BB [This is a checksum on the sequence]

        10         20         30         40         50         60 
TASGKLQRKF LDRFAISMGR GVALGKTYGT LGAASRGATL LQDLLFTEII FAFDRERVPE 

        70         80         90        100        110        120 
RAVHARGTGA HGTFLSYEDW SNLTAASFLS AEGKFTPEMT RFSTVSGARG SADTARDVHG 

       130        140        150        160        170        180 
FATRFYVDEG NFDIVGNNIP VFFIWDVIIE PTLMALHAQK PNPRFHLPRG QQDPNRISDN 

       190        200        210        220        230        240 
LTARGDSLAQ GSQISSERGS PKAYSNTEPN KHRSFRLVTD NGKQFQCSNH WQPLQGFIDL 

       250        260        270        280        290        300 
GVEEAWRFPE EGEGYVAENL FESIELLTVG DEELEIQSMS FNNDLRERFN SSEVTKSSVV 

       310        320        330        340        350        360 
RLVPLITQGK LVFNKNIQML FNEVIGAMFQ PGHIVRGVDF TEDPLLQGRL FSYLDTQLNR 

       370        380        390        400        410        420 
HGPNIQQLGF NRPPRAPIHN NNRDGAGEMI DLPPFASFVE TQEWGAKDIK QTAVGQNKFD 

       430        440        450        460        470        480 
QEHRFSHWKF GVNGFVHTRN DDNVTHARGF FTAPERGQQK KRVAAFDRMF TVVGLSVDGQ 

       490        500        510        520        530        540 
QANSDQYADF DAAAGKKVAK AIGVEAPKPN SNYFHPTDVF GEHIAASGTK YGVPEGNTKG 

       550        560        570        580        590        600 
VLLASVNKPA SIAQGAKLQV VASSGDFAEF FISAKQLNMR EVTQGIIPLV PVLKLAKLDL 

       610        620        630        640        650        660 
GKTFRFQLMQ VGNIEELERF GFDLPDLTDK QVDLSAMGMF ETTFRPTSRA AQFEQGKTKL 

       670        680        690 
VKGLQGKNAF MDRALKQPSN NREKIQRFAD RFAVQD

P81138 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools