[1]	PROTEIN SEQUENCE, SUBUNIT, GLYCOSYLATION, AND COFACTOR. TISSUE=Venom; DOI=10.1006/abbi.1994.1401; PubMed=8080286 [NCBI, ExPASy, EBI, Israel, Japan] Ponnudurai G., Chung M.C.M., Tan N.-H.; "Purification and properties of the L-amino acid oxidase from Malayan pit viper (Calloselasma rhodostoma) venom."; Arch. Biochem. Biophys. 313:373-378(1994).
[2]	PROTEIN SEQUENCE OF 1-15, FUNCTION, SUBUNIT, AND GLYCOSYLATION. TISSUE=Venom; DOI=10.1016/S1357-2725(97)00024-1; PubMed=9304806 [NCBI, ExPASy, EBI, Israel, Japan] Ahn M.-Y., Lee B.M., Kim Y.S.; "Characterization and cytotoxicity of L-amino acid oxidase from the venom of king cobra (Ophiophagus hannah)."; Int. J. Biochem. Cell Biol. 29:911-919(1997).

Comments

FUNCTION: Catalyzes an oxidative deamination of predominantly hydrophobic and aromatic L-amino acids. Has an ability to induce apoptosis and hemorrhage. Has an antibacterial activity (By similarity). Has cytotoxic activity. Induces platelet aggregation.
CATALYTIC ACTIVITY: An L-amino acid + H₂O + O₂ = a 2-oxo acid + NH₃ + H₂O₂.
COFACTOR: FAD.
SUBUNIT: Homodimer.
SUBCELLULAR LOCATION: Secreted.
TISSUE SPECIFICITY: Expressed by the venom gland.
PTM: Glycosylated.
SIMILARITY: Belongs to the flavin monoamine oxidase family. FIG1 subfamily.

Copyright

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Cross-references

3D structure databases

ModBase

P81383.

Ontologies

GO:0001716;	Molecular function: L-amino-acid oxidase activity (inferred from electronic annotation from EC).
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Family and domain databases

BLOCKS

P81383.

Phylogenomic databases

HOVERGEN

P81383; -.

Other

ProtoNet

P81383.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Antibiotic; Antimicrobial; Apoptosis; Blood coagulation; Direct protein sequencing; FAD; Flavoprotein; Glycoprotein; Oxidoreductase; Secreted; Toxin.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 >19`	`>19`	`L-amino-acid oxidase.`	`PRO_0000099871`
`CONFLICT`	`1 1`		`H -> S (in Ref. 2; AA sequence).`
`NON_TER`	`19 19`

Sequence information

Length: 19 AA [This is the length of the partial sequence of the unprocessed precursor]

Molecular weight: 2298 Da [This is the MW of the partial sequence of the unprocessed precursor]

CRC64: DD911A5B414F1427 [This is a checksum on the sequence]

        10 
HVINLEESFQ EPEYENHLA

P81383 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools