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UniProtKB/Swiss-Prot entry P82264

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name DHE3_CHAAC
Primary accession number P82264
Secondary accession numbers None
Integrated into Swiss-Prot on May 4, 2001
Sequence was last modified on March 1, 2001 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 48)
Name and origin of the protein
Protein name Glutamate dehydrogenase, mitochondrial
Synonyms GDH
EC 1.4.1.3
Gene name
Name: glud1
Synonyms: glud
From
Chaenocephalus aceratus (White crocodile fish) [TaxID: 36190] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei; Acanthomorpha; Acanthopterygii; Percomorpha; Perciformes; Notothenioidei; Channichthyidae; Chaenocephalus.
Protein existence 1: Evidence at protein level;
References
[1]
 PROTEIN SEQUENCE.
TISSUE=Liver;
DOI=10.1016/S0167-4838(00)00186-2; PubMed=11087937 [NCBI, ExPASy, EBI, Israel, Japan]
Ciardiello M.A., Camardella L., Carratore V., di Prisco G.;
"L-glutamate dehydrogenase from the antarctic fish Chaenocephalus aceratus. Primary structure, function and thermodynamic characterisation: relationship with cold adaptation.";
Biochim. Biophys. Acta 1543:11-23(2000).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
3D structure databases
HSSP P00367; 1L1F. [HSSP ENTRY / PDB]
SMR P82264; 4-504.
ModBase P82264.
Ontologies
GO
GO:0005759; Cellular component: mitochondrial matrix (inferred from electronic annotation from UniProtKB-SubCell).
QuickGo view.
Family and domain databases
InterPro IPR006095; Glu/Leu/Phe/Val_DHase.
IPR006096; Glu/Leu/Phe/Val_DHase_C.
IPR006097; Glu/Leu/Phe/Val_DHase_dimer.
IPR014362; Glu_DHase.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR11606:SF2; GLFV_DH; 1.
Pfam PF00208; ELFV_dehydrog; 1.
PF02812; ELFV_dehydrog_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000185; Glu_DH; 1.
PRINTS PR00082; GLFDHDRGNASE.
PROSITE PS00074; GLFV_DEHYDROGENASE; FALSE_NEG.
BLOCKS P82264.
Phylogenomic databases
HOVERGEN P82264; -.
Other
ProtoNet P82264.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Direct protein sequencing; GTP-binding; Mitochondrion; NAD; Nucleotide-binding; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   504  504     Glutamate dehydrogenase, mitochondrial. PRO_0000182743
NP_BIND   87    89  3     NAD (By similarity). 
ACT_SITE   129   129        By similarity. 
BINDING   93    93        Substrate (By similarity). 
BINDING   117   117        Substrate (By similarity). 
BINDING   122   122        NAD (By similarity). 
BINDING   198   198        NAD (By similarity). 
BINDING   212   212        GTP (By similarity). 
BINDING   216   216        GTP (By similarity). 
BINDING   265   265        GTP (By similarity). 
BINDING   268   268        GTP (By similarity). 
BINDING   384   384        Substrate (By similarity). 
BINDING   390   390        NAD (By similarity). 
BINDING   396   396        ADP (By similarity). 
BINDING   462   462        ADP (By similarity). 
Sequence information
Length: 504 AA [This is the length of the unprocessed precursor] Molecular weight: 55394 Da [This is the MW of the unprocessed precursor] CRC64: D8E20681642E3E89 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
ADAADKPDDP NFFRMVEGFF DRGASIVEDK LVEDLRTKET PEQKKGRVAG ILRIIKPCNH 

        70         80         90        100        110        120 
VLSLSFPIKR DNGEWEVIEG YRAQHSQHRT PCKGGIRYSM DVSVDEVKAL ASLMTYKCAV 

       130        140        150        160        170        180 
VDVPFGGAKA GVRINTKNYS DNELEKITRR FTIELAKKGF IGPGIDVPAP DMSTGEREMS 

       190        200        210        220        230        240 
WIADTYANTI AHTDINAHAC VTGKPISQGG IHGRISATGR GVFHGIENFM NEASYMSMVG 

       250        260        270        280        290        300 
LTPGVQDKTF VIQGFGNVGL HSMRYLHRFG AKCVGIGEID GAIYNADGID PKALEEYKLQ 

       310        320        330        340        350        360 
NGTIVGFPGA KPYEGSILEA DCDILIPAAG EKQLTRNNAR RIKAKIIAEG ANGPTTPDAD 

       370        380        390        400        410        420 
KIFLENNVMV IPDMYLNAGG VTVSYFEWLK NLNHVSYGRL TFKYERDSNY HLLMSVQESL 

       430        440        450        460        470        480 
ERKFGKQGGP IPVVPTADFQ ARVAGASEKD IVHSGLAYTM ERSARQIMRT ASKHNLGLDI 

       490        500 
RTAAYVNAIE KVFKVYNEAG LTFT
P82264 in FASTA format

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